Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion.
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β-Cell glutamate signaling: Its role in incretin-induced insulin secretionMetabolomics applied to the pancreatic isletDirect arterial injection of hyperpolarized 13 C-labeled substrates into rat tumors for rapid MR detection of metabolism with minimal substrate dilution.Sphingosine kinase 1-interacting protein is a novel regulator of glucose-stimulated insulin secretionGLP-1 receptor signalling promotes β-cell glucose metabolism via mTOR-dependent HIF-1α activationβ cell dysfunction versus insulin resistance in the pathogenesis of type 2 diabetes in East AsiansDICER Inactivation Identifies Pancreatic β-Cell "Disallowed" Genes Targeted by MicroRNAs.Loss of Liver Kinase B1 (LKB1) in Beta Cells Enhances Glucose-stimulated Insulin Secretion Despite Profound Mitochondrial Defects.The new biology of diabetes.The Amplifying Pathway of the β-Cell Contributes to Diet-induced ObesityMetabolic effects of basic fibroblast growth factor in streptozotocin-induced diabetic rats: A (1)H NMR-based metabolomics investigation.Neurotransmitters and Neuropeptides: New Players in the Control of Islet of Langerhans' Cell Mass and Function.Different responses of mouse islets and MIN6 pseudo-islets to metabolic stimulation: a note of caution.Inhibition of the malate-aspartate shuttle in mouse pancreatic islets abolishes glucagon secretion without affecting insulin secretion.The Pancreatic β-Cell: A Bioenergetic Perspective.When β-cells fail: lessons from dedifferentiation.Increased Dynamics of Tricarboxylic Acid Cycle and Glutamate Synthesis in Obese Adipose Tissue: IN VIVO METABOLIC TURNOVER ANALYSIS.Local and regional control of calcium dynamics in the pancreatic islet.cAMP signalling in insulin and glucagon secretion.LKB1 couples glucose metabolism to insulin secretion in mice.Effects of dextromethorphan as add-on to sitagliptin on blood glucose and serum insulin concentrations in individuals with type 2 diabetes mellitus: a randomized, placebo-controlled, double-blinded, multiple crossover, single-dose clinical trialInsulin promoter-driven Gaussia luciferase-based insulin secretion biosensor assay for discovery of β-cell glucose-sensing pathways.Calcium-insensitive splice variants of mammalian E1 subunit of 2-oxoglutarate dehydrogenase complex with tissue-specific patterns of expression.Autocrine, paracrine and necrotic NMDA receptor signalling in mouse pancreatic neuroendocrine tumour cells.Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men.Exocrine pancreas glutamate secretion help to sustain enterocyte nutritional needs under protein restriction.Essential roles of aspartate aminotransferase 1 and vesicular glutamate transporters in β-cell glutamate signaling for incretin-induced insulin secretion.β-Cell signalling and insulin secretagogues: A path for improved diabetes therapy.NMDAR antagonists for the treatment of diabetes mellitus-Current status and future directions.Homogeneous Assays of Second Messenger Signaling and Hormone Secretion Using Thermofluorimetric Methods That Minimize Calibration Burden.
P2860
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P2860
Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Glutamate acts as a key signal ...... to amplify insulin secretion.
@ast
Glutamate acts as a key signal ...... to amplify insulin secretion.
@en
type
label
Glutamate acts as a key signal ...... to amplify insulin secretion.
@ast
Glutamate acts as a key signal ...... to amplify insulin secretion.
@en
prefLabel
Glutamate acts as a key signal ...... to amplify insulin secretion.
@ast
Glutamate acts as a key signal ...... to amplify insulin secretion.
@en
P2093
P2860
P50
P1433
P1476
Glutamate acts as a key signal ...... to amplify insulin secretion.
@en
P2093
Akira Mizoguchi
Eiichiro Fukusaki
Ghupurjan Gheni
Harumi Takahashi
Kazuo Harada
Kazushi Kimura
Kenji Sugawara
Kohtaro Minami
Masahiro Iwasaki
Masahito Ogura
P2860
P304
P356
10.1016/J.CELREP.2014.09.030
P577
2014-10-16T00:00:00Z