Minocycline corrects early, pre-plaque neuroinflammation and inhibits BACE-1 in a transgenic model of Alzheimer's disease-like amyloid pathology.
about
Intracellular Aβ pathology and early cognitive impairments in a transgenic rat overexpressing human amyloid precursor protein: a multidimensional study.Bridge between neuroimmunity and traumatic brain injuryCB1 and CB2 Cannabinoid Receptor Antagonists Prevent Minocycline-Induced Neuroprotection Following Traumatic Brain Injury in MiceMolecular mechanisms of cognitive dysfunction following traumatic brain injuryInteractions between inflammation, sex steroids, and Alzheimer's disease risk factorsLeveraging existing data sets to generate new insights into Alzheimer's disease biology in specific patient subsets.Can oral infection be a risk factor for Alzheimer's disease?Systemic transplantation of human umbilical cord derived mesenchymal stem cells-educated T regulatory cells improved the impaired cognition in AβPPswe/PS1dE9 transgenic mice.LPS-induced proNGF synthesis and release in the N9 and BV2 microglial cells: a new pathway underling microglial toxicity in neuroinflammationMinocycline upregulates cyclic AMP response element binding protein and brain-derived neurotrophic factor in the hippocampus of cerebral ischemia rats and improves behavioral deficitsChronic oral administration of minocycline to sheep with ovine CLN6 neuronal ceroid lipofuscinosis maintains pharmacological concentrations in the brain but does not suppress neuroinflammation or disease progressionOligomeric amyloid β induces IL-1β processing via production of ROS: implication in Alzheimer's disease.Multi-Target-Directed Ligands and other Therapeutic Strategies in the Search of a Real Solution for Alzheimer's Disease.Molecular basis of etiological implications in Alzheimer's disease: focus on neuroinflammation.Microglia and inflammation: conspiracy, controversy or control?Unfolding the promise of translational targeting in neurodegenerative disease.[18F]GE-180 PET Detects Reduced Microglia Activation After LM11A-31 Therapy in a Mouse Model of Alzheimer's Disease.Targeting Tumor Necrosis Factor Alpha for Alzheimer's Disease.Betaine suppressed Aβ generation by altering amyloid precursor protein processing.Cytokines and Cytokine Receptors Involved in the Pathogenesis of Alzheimer's Disease.The Multi-Target Drug M30 Shows Pro-Cognitive and Anti-Inflammatory Effects in a Rat Model of Alzheimer's Disease.Developing BACE-1 inhibitors for FXS.Impact of minocycline on vascularization and visual function in an immature mouse model of ischemic retinopathyProximate Mediators of Microvascular Dysfunction at the Blood-Brain Barrier: Neuroinflammatory Pathways to NeurodegenerationBACE1 inhibition by microdose lithium formulation NP03 rescues memory loss and early stage amyloid neuropathology.Serum levels of soluble TNF-α receptors but not BDNF are associated with apathy symptoms in mild Alzheimer's disease and amnestic mild cognitive impairment.Alzheimer's Disease: The Role of Microglia in Brain Homeostasis and Proteopathy.Minocycline ameliorates D-galactose-induced memory deficits and loss of Arc/Arg3.1 expression.Can inflammation be resolved in Alzheimer's disease?
P2860
Q22001054-A2AC2873-B128-452F-BE3B-E928EF0158ECQ26827612-12EF6214-D7A9-4D4E-960C-B58629D70AF0Q28315817-C2420ECE-9387-490B-970B-75E71A43C379Q28385324-EB2B1B81-3F82-4DDA-ABB3-28CEF414AA7AQ28394967-5CFD6A9A-294B-4A14-BAFA-247B37C8776EQ30995841-259531A7-6932-49CF-82BD-D68699C0BB94Q33361553-3EB5972F-3A61-4159-BF5C-90143EB4CE51Q34919216-6EBE8869-5C97-4EAD-9E78-1F9BC78FC075Q34989278-01F6CA5D-D9D8-48C1-8D3F-62DBBAF098A2Q35142700-B8C1A950-A536-4C13-A387-8B9C9C0734E5Q37071340-56533414-8EC2-4A1E-84A7-089B8C531518Q37424131-50E368FD-D624-43D8-AE9A-8BFB6BCBF74BQ37559812-D9F2B09D-E9DA-4C6A-BE4B-1F01CD46A8A4Q38082670-D760B197-4E2B-4697-B34B-B6D915CE3723Q38227727-DBB41665-5B55-43B8-B15A-31BDBF84D67EQ38362183-DEF59505-82CA-46F1-8B49-9681938F13F3Q38772065-2F668270-D4D9-41E7-9653-10CC87F2EBFDQ38970893-00344831-9228-46CE-BB0E-80AF8DB0F689Q39022771-BE1D9496-801D-4C62-BD07-91C39C7BFF4BQ39023028-49A041FA-94B4-400E-9932-B7FF8CCEA30DQ39182975-7ABD3611-4FA6-42EC-BC2B-450544F0BA4EQ41073215-7645ECBA-5679-47D4-BFFA-8301BB202694Q41311295-22998C18-AA3B-469E-B878-36477312CBD3Q41613567-CA42D07E-AA32-47C7-97D8-CC1929388D28Q41687578-A49636E4-D258-4E5D-8185-32F40B1257B5Q47131749-99AF3760-594F-48F1-A2FB-6B83064D7DE0Q47222390-90DD4BFE-EFBF-436C-AD46-3274FF408354Q48584813-ED389EDF-BA60-495F-BB8A-ADFC962DC2EAQ58793290-EFAE64D8-30FE-4575-8944-0E6A37EB077A
P2860
Minocycline corrects early, pre-plaque neuroinflammation and inhibits BACE-1 in a transgenic model of Alzheimer's disease-like amyloid pathology.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Minocycline corrects early, pr ...... isease-like amyloid pathology.
@ast
Minocycline corrects early, pr ...... isease-like amyloid pathology.
@en
type
label
Minocycline corrects early, pr ...... isease-like amyloid pathology.
@ast
Minocycline corrects early, pr ...... isease-like amyloid pathology.
@en
prefLabel
Minocycline corrects early, pr ...... isease-like amyloid pathology.
@ast
Minocycline corrects early, pr ...... isease-like amyloid pathology.
@en
P2093
P2860
P356
P1476
Minocycline corrects early, pr ...... isease-like amyloid pathology.
@en
P2093
A Claudio Cuello
Adriana Ducatenzeiler
Maria Teresa Ferretti
Simon Allard
Vanessa Partridge
P2860
P2888
P356
10.1186/1742-2094-9-62
P577
2012-04-02T00:00:00Z
P5875
P6179
1030540716