Toxicogenomics and systems toxicology: aims and prospects.
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Workgroup report: Biomonitoring study design, interpretation, and communication--lessons learned and path forward.Inflammatory genomicsPersonalized exposure assessment: promising approaches for human environmental health research.Use of a mixed tissue RNA design for performance assessments on multiple microarray formats.Distinct gene expression profiles in immortalized human urothelial cells exposed to inorganic arsenite and its methylated trivalent metabolitesAdvancing human health risk assessment: integrating recent advisory committee recommendationsDNA adductomicsA mechanistic, model-based approach to safety assessment in clinical developmentData governance in predictive toxicology: A reviewPredictive modeling of chemical hazard by integrating numerical descriptors of chemical structures and short-term toxicity assay dataRole of modern chemistry in sustainable arable crop protectionReconciled rat and human metabolic networks for comparative toxicogenomics and biomarker predictions.Comparative transcriptome analysis of toxic metal responses in Arabidopsis thaliana and the Cd(2+)-hypertolerant facultative metallophyte Arabidopsis halleri.Simultaneous clustering of gene expression data with clinical chemistry and pathological evaluations reveals phenotypic prototypes.Model-based contextualization of in vitro toxicity data quantitatively predicts in vivo drug response in patients.Providing data science support for systems pharmacology and its implications to drug discoveryHeat map visualization of high-density clinical chemistry data.A microarray study of MPP+-treated PC12 Cells: Mechanisms of toxicity (MOT) analysis using bioinformatics tools.MPHASYS: a mouse phenotype analysis system.'Systems toxicology' approach identifies coordinated metabolic responses to copper in a terrestrial non-model invertebrate, the earthworm Lumbricus rubellusRecent progress in toxicogenomics research in South Korea.Creating context for the use of DNA adduct data in cancer risk assessment: I. Data organization.A proteomic analysis of green and white sturgeon larvae exposed to heat stress and selenium.A computational toxicogenomics approach identifies a list of highly hepatotoxic compounds from a large microarray database.Insights into the molecular mechanisms of Polygonum multiflorum Thunb-induced liver injury: a computational systems toxicology approach.A new approach to construct pathway connected networks and its application in dose responsive gene expression profiles of rat liver regulated by 2,4DNT.The role of toxicoproteomics in assessing organ specific toxicity.From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects.Interactions of a pesticide/heavy metal mixture in marine bivalves: a transcriptomic assessment.CSEO - the Cigarette Smoke Exposure Ontology.Biomarkers for drug-induced renal damage and nephrotoxicity-an overview for applied toxicology.Development of a pharmaceutical hepatotoxicity biomarker panel using a discovery to targeted proteomics approach.Use of proteomics for the discovery of early markers of drug toxicity.Functional toxicogenomics: mechanism-centered toxicology.Constructing a fish metabolic network model.ADReCS: an ontology database for aiding standardization and hierarchical classification of adverse drug reaction terms.Functional genomic screening approaches in mechanistic toxicology and potential future applications of CRISPR-Cas9.Identification of genes implicated in methapyrilene-induced hepatotoxicity by comparing differential gene expression in target and nontarget tissue.Toxicogenomics in regulatory ecotoxicology.The evolving field of biodefence: therapeutic developments and diagnostics.
P2860
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P2860
Toxicogenomics and systems toxicology: aims and prospects.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Toxicogenomics and systems toxicology: aims and prospects.
@ast
Toxicogenomics and systems toxicology: aims and prospects.
@en
type
label
Toxicogenomics and systems toxicology: aims and prospects.
@ast
Toxicogenomics and systems toxicology: aims and prospects.
@en
prefLabel
Toxicogenomics and systems toxicology: aims and prospects.
@ast
Toxicogenomics and systems toxicology: aims and prospects.
@en
P2860
P356
P1476
Toxicogenomics and systems toxicology: aims and prospects.
@en
P2093
Jennifer M Fostel
Michael D Waters
P2860
P2888
P304
P356
10.1038/NRG1493
P577
2004-12-01T00:00:00Z