Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets. - Wikidata - wikimedia - TriplyDB

Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets.

Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets.

http://www.wikidata.org/entity/Q35973858

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WZB117 (2-Fluoro-6-(m-hydroxybenzoyloxy) Phenyl m-Hydroxybenzoate) Inhibits GLUT1-mediated Sugar Transport by Binding Reversibly at the Exofacial Sugar Binding Site.End Sequence Analysis Toolkit (ESAT) expands the extractable information from single-cell RNA-seq data.Osteopontin activates the diabetes-associated potassium channel TALK-1 in pancreatic β-cells.GPR142 Agonists Stimulate Glucose-Dependent Insulin Secretion via Gq-Dependent Signaling GPR142 Controls Tryptophan-Induced Insulin and Incretin Hormone Secretion to Improve Glucose Metabolism EphA4 Receptor Forward Signaling Inhibits Glucagon Secretion From α-Cells.Augmented Stat5 Signaling Bypasses Multiple Impediments to Lactogen-Mediated Proliferation in Human β-Cells.Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes.Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic β-cell function via glycogen synthase kinase-3β.Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function.Extracellular CADM1 interactions influence insulin secretion by rat and human islet β-cells and promote clustering of syntaxin-1.Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure.Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.Molecular phenotyping of multiple mouse strains under metabolic challenge uncovers a role for Elovl2 in glucose-induced insulin secretion.Analysis of Purified Pancreatic Islet Beta and Alpha Cell Transcriptomes Reveals 11β-Hydroxysteroid Dehydrogenase (Hsd11b1) as a Novel Disallowed Gene.Effects of type 1 diabetes-associated IFIH1 polymorphisms on MDA5 function and expression.Orphan GPR61, GPR62 and GPR135 receptors and the melatonin MT2 receptor reciprocally modulate their signaling functions Revisiting the immunocytochemical detection of Neurogenin 3 expression in mouse and man.Role of long non-coding RNAs in the determination of β-cell identity.Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice Chronomedicine and type 2 diabetes: shining some light on melatonin.Is a β cell a β cell?Genomics of Islet (Dys)function and Type 2 Diabetes.The Importance of REST for Development and Function of Beta Cells.Local and regional control of calcium dynamics in the pancreatic islet.Melatonin receptors: molecular pharmacology and signaling in the context of system bias.Integrator of Stress Responses Calmodulin Binding Transcription Activator 1 (Camta1) Regulates miR-212/miR-132 Expression and Insulin Secretion.ROCKII inhibition promotes the maturation of human pancreatic beta-like cells Systematic single-cell analysis provides new insights into heterogeneity and plasticity of the pancreas.Different developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth.Alpha TC1 and Beta-TC-6 genomic profiling uncovers both shared and distinct transcriptional regulatory features with their primary islet counterparts.Single-Cell Mass Cytometry Analysis of the Human Endocrine Pancreas.Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas.Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns.Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.Sirolimus induces depletion of intracellular calcium stores and mitochondrial dysfunction in pancreatic beta cells.A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells.

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Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets.

http://www.wikidata.org/entity/Q35973858

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

Novel Observations From Next-G ...... and Fetal Islet Cell Subsets.

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Novel Observations From Next-G ...... and Fetal Islet Cell Subsets.

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Novel Observations From Next-G ...... and Fetal Islet Cell Subsets.

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Novel Observations From Next-G ...... and Fetal Islet Cell Subsets.

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Novel Observations From Next-G ...... and Fetal Islet Cell Subsets.

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Novel Observations From Next-G ...... and Fetal Islet Cell Subsets.

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Novel Observations From Next-G ...... and Fetal Islet Cell Subsets.

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Anetta Nowosielska

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Anthony J Cura

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Dale L Greiner

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David M Blodgett

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David M Harlan

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Manuel G Garber

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Philip diIorio

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Roger J Davis

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Sally C Kent

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P2860

Projections of global mortality and burden of disease from 2002 to 2030

Myeloid-related protein-8/14 is critical for the biological response to vascular injury

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

Beyond model antigens: high-dimensional methods for the analysis of antigen-specific T cells

Fast gapped-read alignment with Bowtie 2

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Systems biology approach reveals genome to phenome correlation in type 2 diabetes

GLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein Bim

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants

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3172-3181

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10.2337/DB15-0039

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9

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64

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Alper Kucukural

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2015-04-30T00:00:00Z

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25931473

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