A large and distinct rotation of the myosin light chain domain occurs upon muscle contraction.
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The myosin power strokeMyosin V exhibits a high duty cycle and large unitary displacementElectron paramagnetic resonance: a high-resolution tool for muscle physiology.A mutant heterodimeric myosin with one inactive head generates maximal displacement.Polarized fluorescence depletion reports orientation distribution and rotational dynamics of muscle cross-bridges.The biochemical kinetics underlying actin movement generated by one and many skeletal muscle myosin moleculesThe unique properties of tonic smooth muscle emerge from intrinsic as well as intermolecular behaviors of Myosin molecules.Myosin conformational states determined by single fluorophore polarizationStructural dynamics of the myosin relay helix by time-resolved EPR and FRET.Site-directed spin labeling reveals a conformational switch in the phosphorylation domain of smooth muscle myosinConformational change of the actomyosin complex drives the multiple stepping movementBackward movements of cross-bridges by application of stretch and by binding of MgADP to skeletal muscle fibers in the rigor state as studied by x-ray diffraction.Mechanochemical coupling in spin-labeled, active, isometric muscleCaATP as a substrate to investigate the myosin lever arm hypothesis of force generation.Actin and temperature effects on the cross-linking of the SH1-SH2 helix in myosin subfragment 1.Conformational selection during weak binding at the actin and myosin interface.Thermodynamics and kinetics of a molecular motor ensembleMolecular dynamics simulation of site-directed spin labeling: experimental validation in muscle fibers.Mechanical defects of muscle fibers with myosin light chain mutants that cause cardiomyopathyMyosin regulatory domain orientation in skeletal muscle fibers: application of novel electron paramagnetic resonance spectral decomposition and molecular modeling methodsThe sliding filament model: 1972-2004.Structural changes of actin-bound myosin heads after a quick length change in frog skeletal muscle.Coordination of the two heads of myosin during muscle contractionImpact of familial hypertrophic cardiomyopathy-linked mutations in the NH2 terminus of the RLC on β-myosin cross-bridge mechanicsStructural changes of cross-bridges on transition from isometric to shortening state in frog skeletal muscle.Functional, structural, and chemical changes in myosin associated with hydrogen peroxide treatment of skeletal muscle fibers.Amplitude of the actomyosin power stroke depends strongly on the isoform of the myosin essential light chainThree distinct actin-attached structural states of myosin in muscle fibers.New angle on myosin.A paramagnetic molecular voltmeter.Conformationally trapping the actin-binding cleft of myosin with a bifunctional spin labelBiological Nanomotors with a Revolution, Linear, or Rotation Motion MechanismDirect real-time detection of the actin-activated power stroke within the myosin catalytic domainOrientation of the essential light chain region of myosin in relaxed, active, and rigor muscleStructural dynamics of the actomyosin complex probed by a bifunctional spin label that cross-links SH1 and SH2.Invertebrate muscles: thin and thick filament structure; molecular basis of contraction and its regulation, catch and asynchronous muscle.Removal of the cardiac myosin regulatory light chain increases isometric force productionSite-directed spectroscopic probes of actomyosin structural dynamics.Molecular machines directly observed by high-speed atomic force microscopy.Sucrose increases the activation energy barrier for actin-myosin strong binding.
P2860
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P2860
A large and distinct rotation of the myosin light chain domain occurs upon muscle contraction.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
A large and distinct rotation ...... ccurs upon muscle contraction.
@ast
A large and distinct rotation ...... ccurs upon muscle contraction.
@en
type
label
A large and distinct rotation ...... ccurs upon muscle contraction.
@ast
A large and distinct rotation ...... ccurs upon muscle contraction.
@en
prefLabel
A large and distinct rotation ...... ccurs upon muscle contraction.
@ast
A large and distinct rotation ...... ccurs upon muscle contraction.
@en
P2093
P2860
P356
P1476
A large and distinct rotation ...... ccurs upon muscle contraction.
@en
P2093
D D Thomas
I Brust-Mascher
L E LaConte
S Ramachandran
P2860
P304
P356
10.1073/PNAS.95.6.2944
P407
P577
1998-03-01T00:00:00Z