about
A novel neutrophil-specific PET imaging agent: cFLFLFK-PEG-64Cu.Near-infrared-labeled peptide multimer functions as phage mimic for high affinity, specific targeting of colonic adenomas in vivo (with videos).Convenient and Efficient Synthesis of a Lanthanide-Coordinated, Diethylene Triamine Pentaacetic Acid Labeled Biopolymer as an Assay for the Cholecystokinin B Receptor.Synthesis and evaluation of cholecystokinin trimers: a multivalent approach to pancreatic cancer detection and treatmentExpanding the utility of beta-galactosidase complementation: piece by piece.Synthesis and characterization of a Eu-DTPA-PEGO-MSH(4) derivative for evaluation of binding of multivalent molecules to melanocortin receptors.A sucrose-derived scaffold for multimerization of bioactive peptidesA solanesol-derived scaffold for multimerization of bioactive peptidesHeterobivalent ligands target cell-surface receptor combinations in vivo.Organic chemistry and biology: chemical biology through the eyes of collaboration.Synthesis and evaluation of bivalent ligands for binding to the human melanocortin-4 receptor.Macrocyclic chelator assembled RGD multimers for tumor targeting.Cystine-knot peptides targeting cancer-relevant human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4).Tentacle probes: eliminating false positives without sacrificing sensitivity.Comparative study of 64Cu/NOTA-[D-Tyr6,βAla11,Thi13,Nle14]BBN(6-14) monomer and dimers for prostate cancer PET imagingCell-specific targeting by heterobivalent ligands.Squalene-derived flexible linkers for bioactive peptides.Potent inhibition of tau fibrillization with a multivalent ligand.Development of Follicle-Stimulating Hormone Receptor Binding Probes to Image Ovarian Xenografts.Design, synthesis, and biological studies of efficient multivalent melanotropin ligands: tools toward melanoma diagnosis and treatment.Design, synthesis, and validation of a branched flexible linker for bioactive peptides.Synthesis and evaluation of bivalent NDP-alpha-MSH(7) peptide ligands for binding to the human melanocortin receptor 4 (hMC4R).Multivalent Interactions: Synthesis and Evaluation of Melanotropin Multimers - Tools for Melanoma Targeting.Peptide heterodimers for molecular imaging.Enhanced targeting with heterobivalent ligandsTentacle probe sandwich assay in porous polymer monolith improves specificity, sensitivity and kinetics.Nanovehicular intracellular delivery systems.New technologies for human cancer imaging.Heterobivalent ligands crosslink multiple cell-surface receptors: the human melanocortin-4 and delta-opioid receptors.Solid-Phase Synthesis of Heterobivalent Ligands Targeted to Melanocortin and Cholecystokinin Receptors.Design of peptide and peptidomimetic ligands with novel pharmacological activity profiles.Radiolabeled heterobivalent peptidic ligands: an approach with high future potential for in vivo imaging and therapy of malignant diseases.Phosphinic acid functionalized polyazacycloalkane chelators for radiodiagnostics and radiotherapeutics: unique characteristics and applications.Gene expression profiling-based identification of cell-surface targets for developing multimeric ligands in pancreatic cancer.Dimeric DOTA-alpha-melanocyte-stimulating hormone analogs: synthesis and in vivo characteristics of radiopeptides with high in vitro activity.Rigid linkers for bioactive peptides.Specificity and mobility of biomacromolecular, multivalent constructs for cellular targeting.Development of melanoma-targeted polymer micelles by conjugation of a melanocortin 1 receptor (MC1R) specific ligand.A cyclen-based tetraphosphinate chelator for the preparation of radiolabeled tetrameric bioconjugates.Development of Targeting Ligands for HER2 Receptor: Simplified Receptor Model Employed for Selecting Highly Specific Molecules
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Hitting multiple targets with multimeric ligands.
@ast
Hitting multiple targets with multimeric ligands.
@en
type
label
Hitting multiple targets with multimeric ligands.
@ast
Hitting multiple targets with multimeric ligands.
@en
prefLabel
Hitting multiple targets with multimeric ligands.
@ast
Hitting multiple targets with multimeric ligands.
@en
P2093
P2860
P356
P1476
Hitting multiple targets with multimeric ligands.
@en
P2093
Eugene Mash
Haiyong Han
Heather L Handl
Josef Vagner
Robert J Gillies
Victor J Hruby
P2860
P304
P356
10.1517/14728222.8.6.565
P407
P577
2004-12-01T00:00:00Z