A dually active anthrax vaccine that confers protection against both bacilli and toxins.
about
Binary bacterial toxins: biochemistry, biology, and applications of common Clostridium and Bacillus proteinsAnthrax vaccine design: strategies to achieve comprehensive protection against spore, bacillus, and toxinRabies virus glycoprotein as a carrier for anthrax protective antigenAnthrax vaccination strategiesMonoclonal antibody therapies against anthraxIgG subclass and heavy chain domains contribute to binding and protection by mAbs to the poly γ-D-glutamic acid capsular antigen of Bacillus anthracis.Identification of a second collagen-like glycoprotein produced by Bacillus anthracis and demonstration of associated spore-specific sugars.Effects of spontaneous deamidation on the cytotoxic activity of the Bacillus anthracis protective antigen.Immunogenicity and protective efficacy of Bacillus anthracis poly-gamma-D-glutamic acid capsule covalently coupled to a protein carrier using a novel triazine-based conjugation strategy.Protective and immunochemical activities of monoclonal antibodies reactive with the Bacillus anthracis polypeptide capsuleMucosal immunization with a novel nanoemulsion-based recombinant anthrax protective antigen vaccine protects against Bacillus anthracis spore challengeA single immunization with a dry powder anthrax vaccine protects rabbits against lethal aerosol challengeBacillus anthracis peptidoglycan stimulates an inflammatory response in monocytes through the p38 mitogen-activated protein kinase pathway.Capsule anchoring in Bacillus anthracis occurs by a transpeptidation reaction that is inhibited by capsidin.Efficacy of a vaccine based on protective antigen and killed spores against experimental inhalational anthraxAnthrax prevention and treatment: utility of therapy combining antibiotic plus vaccine.Bacillus anthracis capsule activates caspase-1 and induces interleukin-1beta release from differentiated THP-1 and human monocyte-derived dendritic cells.Capsule synthesis by Bacillus anthracis is required for dissemination in murine inhalation anthraxKey role of poly-gamma-DL-glutamic acid in immune evasion and virulence of Staphylococcus epidermidis.Combining anthrax vaccine and therapy: a dominant-negative inhibitor of anthrax toxin is also a potent and safe immunogen for vaccines.Oral spore vaccine based on live attenuated nontoxinogenic Bacillus anthracis expressing recombinant mutant protective antigen.Pre- and postexposure protection against virulent anthrax infection in mice by humanized monoclonal antibodies to Bacillus anthracis capsuleSearch for Bacillus anthracis potential vaccine candidates by a functional genomic-serologic screen.Dermatan sulfate interacts with dead cells and regulates CD5(+) B-cell fate: implications for a key role in autoimmunityImmunoproteomically identified GBAA_0345, alkyl hydroperoxide reductase subunit C is a potential target for multivalent anthrax vaccine.The poly-γ-D-glutamic acid capsule of Bacillus anthracis enhances lethal toxin activity.Toxin-deficient mutants of Bacillus anthracis are lethal in a murine model for pulmonary anthraxEpitope-focused peptide immunogens in human use adjuvants protect rabbits from experimental inhalation anthrax.Bacillus anthracis Capsular Conjugates Elicit Chimpanzee Polyclonal Antibodies That Protect Mice from Pulmonary Anthrax.Acetalated Dextran Microparticulate Vaccine Formulated via Coaxial Electrospray Preserves Toxin Neutralization and Enhances Murine Survival Following Inhalational Bacillus Anthracis Exposure.Expression of either lethal toxin or edema toxin by Bacillus anthracis is sufficient for virulence in a rabbit model of inhalational anthraxSelection and evaluation of the immunogenicity of protective antigen mutants as anthrax vaccine candidates.In vivo fate and distribution of poly-gamma-D-glutamic acid, the capsular antigen from Bacillus anthracis.An adenovirus-vectored nasal vaccine confers rapid and sustained protection against anthrax in a single-dose regimenSortase-conjugation generates a capsule vaccine that protects guinea pigs against Bacillus anthracisDetoxified lethal toxin as a potential mucosal vaccine against anthrax.Recombinant vaccine displaying the loop-neutralizing determinant from protective antigen completely protects rabbits from experimental inhalation anthraxPotential biological targets of Bacillus anthracis in anti-infective approaches against the threat of bioterrorism.Killed but metabolically active Bacillus anthracis vaccines induce broad and protective immunity against anthraxmAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia.
P2860
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P2860
A dually active anthrax vaccine that confers protection against both bacilli and toxins.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
A dually active anthrax vaccine that confers protection against both bacilli and toxins.
@ast
A dually active anthrax vaccine that confers protection against both bacilli and toxins.
@en
type
label
A dually active anthrax vaccine that confers protection against both bacilli and toxins.
@ast
A dually active anthrax vaccine that confers protection against both bacilli and toxins.
@en
prefLabel
A dually active anthrax vaccine that confers protection against both bacilli and toxins.
@ast
A dually active anthrax vaccine that confers protection against both bacilli and toxins.
@en
P2093
P2860
P356
P1476
A dually active anthrax vaccine that confers protection against both bacilli and toxins.
@en
P2093
Gi-Eun Rhie
John J Mekalanos
Julia Y Wang
Michael H Roehrl
Michael Mourez
P2860
P304
10925-10930
P356
10.1073/PNAS.1834478100
P407
P577
2003-09-05T00:00:00Z