Pharmacology of brain Na+/Ca2+ exchanger: from molecular biology to therapeutic perspectives.
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Ca2+-dependent mechanisms of presynaptic control at central synapsesSilencing or knocking out the Na(+)/Ca(2+) exchanger-3 (NCX3) impairs oligodendrocyte differentiation.Ionic homeostasis in brain conditioningCurrent understanding of TRPM7 pharmacology and drug development for strokeCa2+ regulation of ion transport in the Na+/Ca2+ exchangerInhibitory interaction of the plasma membrane Na+/Ca2+ exchangers with the 14-3-3 proteinsAmiloride and SN-6 suppress audiogenic seizure susceptibility in genetically epilepsy-prone ratsThe Concise Guide to PHARMACOLOGY 2013/14: transporters.Dual effect of Nai+ on Ca2+ influx through the Na+/Ca2+ exchanger in dialyzed squid axons. Experimental data confirming the validity of the squid axon kinetic model.Emerging Roles of microRNAs in Ischemic Stroke: As Possible Therapeutic AgentsThe TRPC channel blocker SKF 96365 inhibits glioblastoma cell growth by enhancing reverse mode of the Na(+) /Ca(2+) exchanger and increasing intracellular Ca(2+).Blockade of the sodium calcium exchanger exhibits anticonvulsant activity in a pilocarpine model of acute seizures in ratsEndoplasmic reticulum refilling and mitochondrial calcium extrusion promoted in neurons by NCX1 and NCX3 in ischemic preconditioning are determinant for neuroprotection.Increased Na+/Ca2+ exchanger activity promotes resistance to excitotoxicity in cortical neurons of the ground squirrel (a Hibernator).Regulation of dendritic calcium release in striatal spiny projection neuronsAmiloride improves locomotor recovery after spinal cord injury.MicroRNA-103-1 selectively downregulates brain NCX1 and its inhibition by anti-miRNA ameliorates stroke damage and neurological deficits.Meta-analysis of new genome-wide association studies of colorectal cancer riskCa2+ toxicity due to reverse Na+/Ca2+ exchange contributes to degeneration of neurites of DRG neurons induced by a neuropathy-associated Nav1.7 mutationNeuroprotection Against Diisopropylfluorophosphate in Acute Hippocampal Slices.Disruption of ionic and cell volume homeostasis in cerebral ischemia: The perfect stormProbing the role of the sodium/calcium exchanger in pentylenetetrazole-induced generalized seizures in rats.Na (+) /Ca (2+) Exchanger 3 is Downregulated in the Hippocampus and Cerebrocortex of Rats with Hyperthermia-induced ConvulsionDifferential modification of the phospholipid profile by transient ischemia in rat hippocampal CA1 and CA3 regions.ncx1, ncx2, and ncx3 gene product expression and function in neuronal anoxia and brain ischemia.Sodium-calcium exchangers in rat trigeminal ganglion neurons.Traumatic brain injury causes a long-lasting calcium (Ca2+)-plateau of elevated intracellular Ca levels and altered Ca2+ homeostatic mechanisms in hippocampal neurons surviving brain injury.Postsynaptic mechanisms underlying the excitatory action of histamine on medial vestibular nucleus neurons in rats.Ion transporters and ischemic mitochondrial dysfunction.Na,K-ATPase activity regulates AMPA receptor turnover through proteasome-mediated proteolysis.Ca(2+) signaling evoked by activation of Na(+) channels and Na(+)/Ca(2+) exchangers is required for GABA-induced NG2 cell migration.Collapsin response mediator protein 2 (CRMP2) interacts with N-methyl-D-aspartate (NMDA) receptor and Na+/Ca2+ exchanger and regulates their functional activity.Functional comparison of the reverse mode of Na+/Ca2+ exchangers NCX1.1 and NCX1.5 expressed in CHO cells.Ionic transporter activity in astrocytes, microglia, and oligodendrocytes during brain ischemiaDoes Na⁺/Ca²⁺ exchanger, NCX, represent a new druggable target in stroke intervention?An efficient signal-on aptamer-based biosensor for adenosine triphosphate detection using graphene oxide both as an electrochemical and electrochemiluminescence signal indicator.The role of Na+/Ca2+ exchanger subtypes in neuronal ischemic injury.Novel Cellular Mechanisms for Neuroprotection in Ischemic Preconditioning: A View from Inside Organelles.Endoplasmic reticulum stress in brain ischemia.Essential role of Na+/Ca2+ exchanger 1 in smoking-induced growth and migration of esophageal squamous cell carcinoma.
P2860
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P2860
Pharmacology of brain Na+/Ca2+ exchanger: from molecular biology to therapeutic perspectives.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Pharmacology of brain Na+/Ca2+ ...... y to therapeutic perspectives.
@ast
Pharmacology of brain Na+/Ca2+ ...... y to therapeutic perspectives.
@en
type
label
Pharmacology of brain Na+/Ca2+ ...... y to therapeutic perspectives.
@ast
Pharmacology of brain Na+/Ca2+ ...... y to therapeutic perspectives.
@en
prefLabel
Pharmacology of brain Na+/Ca2+ ...... y to therapeutic perspectives.
@ast
Pharmacology of brain Na+/Ca2+ ...... y to therapeutic perspectives.
@en
P356
P1476
Pharmacology of brain Na+/Ca2+ ...... gy to therapeutic perspectives
@en
P2093
Di Renzo GF
P304
P356
10.1124/PR.56.4.5
P577
2004-12-01T00:00:00Z