Age-dependent in vivo conversion of mouse cochlear pillar and Deiters' cells to immature hair cells by Atoh1 ectopic expression
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Gene therapy for the inner earBeyond generalized hair cells: molecular cues for hair cell typesThe genetics of hair cell development and regenerationSegregating neural and mechanosensory fates in the developing ear: patterning, signaling, and transcriptional control.Sensory hair cell development and regeneration: similarities and differencesHair cell regeneration after ATOH1 gene therapy in the cochlea of profoundly deaf adult guinea pigs.Induced regeneration--the progress and promise of direct reprogramming for heart repair.Characterization of the transcriptome of nascent hair cells and identification of direct targets of the Atoh1 transcription factorA historical to present-day account of efforts to answer the question: "what puts the brakes on mammalian hair cell regeneration?"In Vivo Interplay between p27Kip1, GATA3, ATOH1, and POU4F3 Converts Non-sensory Cells to Hair Cells in Adult Mice.A central to peripheral progression of cell cycle exit and hair cell differentiation in the developing mouse cristae.Gfi1Cre mice have early onset progressive hearing loss and induce recombination in numerous inner ear non-hair cells.Atoh1 as a Coordinator of Sensory Hair Cell Development and Regeneration in the Cochlea.Mammalian Cochlear Hair Cell Regeneration and Ribbon Synapse ReformationTranscriptomic Analysis of Mouse Cochlear Supporting Cell Maturation Reveals Large-Scale Changes in Notch Responsiveness Prior to the Onset of Hearing.Nonviral Reprogramming of Human Wharton's Jelly Cells Reveals Differences Between ATOH1 Homologues.DAPT mediates atoh1 expression to induce hair cell-like cells.Manipulating cell fate in the cochlea: a feasible therapy for hearing loss.In Vivo Cochlear Hair Cell Generation and Survival by Coactivation of β-Catenin and Atoh1The Role of Atonal Factors in Mechanosensory Cell Specification and FunctionHistone deacetylase inhibition protects hearing against acute ototoxicity by activating the Nf-κB pathway.Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivoSox2-CreER mice are useful for fate mapping of mature, but not neonatal, cochlear supporting cells in hair cell regeneration studies.Spontaneous regeneration of cochlear supporting cells after neonatal ablation ensures hearing in the adult mouse.Auditory hair cell-specific deletion of p27Kip1 in postnatal mice promotes cell-autonomous generation of new hair cells and normal hearing.Responses to cell loss become restricted as the supporting cells in mammalian vestibular organs grow thick junctional actin bands that develop high stabilityEpigenetic regulation in the inner ear and its potential roles in development, protection, and regeneration.Therapeutic potential of a gamma-secretase inhibitor for hearing restoration in a guinea pig model with noise-induced hearing lossSensational placodes: neurogenesis in the otic and olfactory systems.Genetic rescue of Muenke syndrome model hearing loss reveals prolonged FGF-dependent plasticity in cochlear supporting cell fates.Inner ear supporting cells: rethinking the silent majority.The myc road to hearing restoration.A brief history of hair cell regeneration research and speculations on the futureChanges in the adult vertebrate auditory sensory epithelium after trauma.Postnatal development, maturation and aging in the mouse cochlea and their effects on hair cell regeneration.Generation of hair cells in neonatal mice by β-catenin overexpression in Lgr5-positive cochlear progenitors.Grand challenges in pediatric otolaryngology.Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochleaIn vivo visualization of Notch1 proteolysis reveals the heterogeneity of Notch1 signaling activity in the mouse cochlea.MYC gene delivery to adult mouse utricles stimulates proliferation of postmitotic supporting cells in vitro.
P2860
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P2860
Age-dependent in vivo conversion of mouse cochlear pillar and Deiters' cells to immature hair cells by Atoh1 ectopic expression
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Age-dependent in vivo conversi ...... ls by Atoh1 ectopic expression
@ast
Age-dependent in vivo conversi ...... ls by Atoh1 ectopic expression
@en
type
label
Age-dependent in vivo conversi ...... ls by Atoh1 ectopic expression
@ast
Age-dependent in vivo conversi ...... ls by Atoh1 ectopic expression
@en
prefLabel
Age-dependent in vivo conversi ...... ls by Atoh1 ectopic expression
@ast
Age-dependent in vivo conversi ...... ls by Atoh1 ectopic expression
@en
P2093
P2860
P1476
Age-dependent in vivo conversi ...... ls by Atoh1 ectopic expression
@en
P2093
Brandon C Cox
Frederique Zindy
Jennifer A Dearman
Lingli Zhang
Olivier Ayrault
Zhiyong Liu
P2860
P304
P356
10.1523/JNEUROSCI.0818-12.2012
P407
P577
2012-05-01T00:00:00Z