Calpain activation impairs neuromuscular transmission in a mouse model of the slow-channel myasthenic syndrome
about
Decoding pathogenesis of slow-channel congenital myasthenic syndromes using recombinant expression and mice models.Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGSRegulation and physiological roles of the calpain system in muscular disordersDok-7 myasthenia: phenotypic and molecular genetic studies in 16 patients.Decremental response to high-frequency trains of acetylcholine pulses but unaltered fractional Ca2+ currents in a panel of "slow-channel syndrome" nicotinic receptor mutants.Skeletal muscle calpain acts through nitric oxide and neural miRNAs to regulate acetylcholine release in motor nerve terminals.Transgenic mouse model reveals an unsuspected role of the acetylcholine receptor in statin-induced neuromuscular adverse drug reactions.Skeletal muscle IP3R1 receptors amplify physiological and pathological synaptic calcium signals.Fluoxetine is neuroprotective in slow-channel congenital myasthenic syndrome.Mutations Causing Slow-Channel Myasthenia Reveal That a Valine Ring in the Channel Pore of Muscle AChR is Optimized for Stabilizing Channel Gating.Further evidence for the role of IP 3R 1 in regulating subsynaptic gene expression and neuromuscular transmission.Animal Models of the Neuromuscular Junction, Vitally Informative for Understanding Function and the Molecular Mechanisms of Congenital Myasthenic Syndromes.
P2860
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P2860
Calpain activation impairs neuromuscular transmission in a mouse model of the slow-channel myasthenic syndrome
description
2007 nî lūn-bûn
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2007年の論文
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2007年論文
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2007年論文
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2007年論文
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2007年論文
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2007年論文
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2007年论文
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2007年论文
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2007年论文
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name
Calpain activation impairs neu ...... ow-channel myasthenic syndrome
@ast
Calpain activation impairs neu ...... ow-channel myasthenic syndrome
@en
type
label
Calpain activation impairs neu ...... ow-channel myasthenic syndrome
@ast
Calpain activation impairs neu ...... ow-channel myasthenic syndrome
@en
prefLabel
Calpain activation impairs neu ...... ow-channel myasthenic syndrome
@ast
Calpain activation impairs neu ...... ow-channel myasthenic syndrome
@en
P2093
P2860
P356
P1476
Calpain activation impairs neu ...... ow-channel myasthenic syndrome
@en
P2093
Bhupinder P S Vohra
Bula J Bhattacharyya
Christopher M Gomez
Elena Kudryashova
Jason S Groshong
Melissa J Spencer
Richard J Miller
Robert L Wollmann
Roberto Zayas
P2860
P304
P356
10.1172/JCI30383
P407
P577
2007-10-01T00:00:00Z