The chemistry and biology of nitroxyl (HNO): a chemically unique species with novel and important biological activity.
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Nitroxyl (HNO): A Reduced Form of Nitric Oxide with Distinct Chemical, Pharmacological, and Therapeutic PropertiesBiochemistry of mobile zinc and nitric oxide revealed by fluorescent sensors.Acidity and hydrogen exchange dynamics of iron(II)-bound nitroxyl in aqueous solution.Solid-phase synthesis provides a modular, lysine-based platform for fluorescent discrimination of nitroxyl and biological thiols.Integration of molecular and enzymatic catalysts on graphene for biomimetic generation of antithrombotic speciesThe specificity of nitroxyl chemistry is unique among nitrogen oxides in biological systems.Cysteine-mediated redox signaling: chemistry, biology, and tools for discoveryRapid and selective nitroxyl (HNO) trapping by phosphines: kinetics and new aqueous ligations for HNO detection and quantitation.The pharmacology of nitroxyl (HNO) and its therapeutic potential: not just the Janus face of NOHow to control NO production in cells: N(omega),N(omega)-dimethyl-L-arginine dimethylaminohydrolase as a novel drug target.Recent advances in the chemical biology of nitroxyl (HNO) detection and generation.Identification of nitroxyl-induced modifications in human platelet proteins using a novel mass spectrometric detection method.Hydroxamic acids (therapeutics and mechanism): chemistry, acyl nitroso, nitroxyl, reactive oxygen species, and cell signaling.Cysteine-mediated redox signalling in the mitochondria.Discriminative EPR detection of NO and HNO by encapsulated nitronyl nitroxides.A fast-response, highly sensitive and selective fluorescent probe for the ratiometric imaging of nitroxyl in living cells.Nitroxyl (HNO) acutely activates the glucose uptake activity of GLUT1.Direct detection of nitroxyl in aqueous solution using a tripodal copper(II) BODIPY complex.Nitroxyl accelerates the oxidation of oxyhemoglobin by nitriteHydrogen sulfide interacts with nitric oxide in the heart: possible involvement of nitroxyl.Brisk production of nitric oxide and associated formation of S-nitrosothiols in early hemorrhage.On the possible biological relevance of HSNO isomers: a computational investigation.Reactions of the NO redox forms NO+, *NO and HNO (protonated NO-) with the melatonin metabolite N1-acetyl-5-methoxykynuramine.Hidden complexities in the reaction of H2O2 and HNO revealed by ab initio quantum chemical investigations.Modeling of S-Nitrosothiol-Thiol Reactions of Biological Significance: HNO Production by S-Thiolation Requires a Proton Shuttle and Stabilization of Polar Intermediates.The lowest-lying electronic singlet and triplet potential energy surfaces for the HNO-NOH system: energetics, unimolecular rate constants, tunneling and kinetic isotope effects for the isomerization and dissociation reactions.A highly sensitive and reductant-resistant fluorescent probe for nitroxyl in aqueous solution and serum.Oxygen metabolism by neuronal nitric-oxide synthase.A thermally stable {FeNO}8complex: properties and biological reactivity of reduced MNO systems
P2860
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P2860
The chemistry and biology of nitroxyl (HNO): a chemically unique species with novel and important biological activity.
description
2005 nî lūn-bûn
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2005年の論文
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2005年論文
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2005年論文
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2005年論文
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2005年論文
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2005年論文
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2005年论文
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name
The chemistry and biology of n ...... important biological activity.
@ast
The chemistry and biology of n ...... important biological activity.
@en
type
label
The chemistry and biology of n ...... important biological activity.
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The chemistry and biology of n ...... important biological activity.
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prefLabel
The chemistry and biology of n ...... important biological activity.
@ast
The chemistry and biology of n ...... important biological activity.
@en
P2093
P2860
P356
P1433
P1476
The chemistry and biology of n ...... important biological activity.
@en
P2093
Andrew S Dutton
Jon M Fukuto
Kendall N Houk
P2860
P304
P356
10.1002/CBIC.200400271
P577
2005-04-01T00:00:00Z