Integrin-linked kinase: a cancer therapeutic target unique among its ILK.
about
Matricellular proteins: a sticky affair with cancersType I collagen promotes epithelial-mesenchymal transition through ILK-dependent activation of NF-kappaB and LEF-1Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signallingStructural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinaseThe structural basis of integrin-linked kinase-PINCH interactionsIntegrin-linked kinase localizes to the centrosome and regulates mitotic spindle organizationResearch advances on structure and biological functions of integrinsIs there a role for epidermal growth factor receptor tyrosine kinase inhibitors in epidermal growth factor receptor wild-type non-small cell lung cancer?The on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migrationThe potential of sarcospan in adhesion complex replacement therapeutics for the treatment of muscular dystrophyIntegrin-linked kinase regulates interphase and mitotic microtubule dynamicsThe Pseudoactive Site of ILK Is Essential for Its Binding to α-Parvin and Localization to Focal AdhesionsDetermination of Multicomponent Protein Structures in Solution Using Global Orientation and Shape RestraintsStructural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinaseIntegrins in the Spotlight of CancerActopaxin interacts with TESK1 to regulate cell spreading on fibronectinMolecular dissection of PINCH-1 reveals a mechanism of coupling and uncoupling of cell shape modulation and survivalPhosphorylation-dependent regulation of nuclear localization and functions of integrin-linked kinaseA proteomics approach to identifying key protein targets involved in VEGF inhibitor mediated attenuation of bleomycin-induced pulmonary fibrosisPurification and SAXS analysis of the integrin linked kinase, PINCH, parvin (IPP) heterotrimeric complexSimulation predicts IGFBP2-HIF1α interaction drives glioblastoma growthComparative Gene Expression Profiling of Primary and Metastatic Renal Cell Carcinoma Stem Cell-Like Cancer CellstPA is a potent mitogen for renal interstitial fibroblasts: role of beta1 integrin/focal adhesion kinase signalingIntegrin-linked kinase mediates bone morphogenetic protein 7-dependent renal epithelial cell morphogenesisSnail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3Cytokeratin 8 ectoplasmic domain binds urokinase-type plasminogen activator to breast tumor cells and modulates their adhesion, growth and invasiveness.Engineering the heart: evaluation of conductive nanomaterials for improving implant integration and cardiac functionLIMD2 is a small LIM-only protein overexpressed in metastatic lesions that regulates cell motility and tumor progression by directly binding to and activating the integrin-linked kinaseData-Driven Discovery of Extravasation Pathway in Circulating Tumor Cells.SPARC regulates extracellular matrix organization through its modulation of integrin-linked kinase activity.The small molecule inhibitor QLT0267 Radiosensitizes squamous cell carcinoma cells of the head and neck.Integrin-linked kinase functions as a downstream signal of platelet-derived growth factor to regulate actin polymerization and vascular smooth muscle cell migration.Inhibition of Integrin-HER2 signaling by Cucurbitacin B leads to in vitro and in vivo breast tumor growth suppressionTalin1 promotes tumor invasion and metastasis via focal adhesion signaling and anoikis resistance.Anoikis disruption of focal adhesion-Akt signaling impairs renal cell carcinoma.Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neuronsMechanisms of the epithelial-mesenchymal transition by TGF-betaIntegrin-linked kinase overexpression and its oncogenic role in promoting tumorigenicity of hepatocellular carcinoma.Angiopoietin-2 stimulates breast cancer metastasis through the alpha(5)beta(1) integrin-mediated pathwaySignificance of thymosin β4 and implication of PINCH-1-ILK-α-parvin (PIP) complex in human dilated cardiomyopathy
P2860
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P2860
Integrin-linked kinase: a cancer therapeutic target unique among its ILK.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Integrin-linked kinase: a cancer therapeutic target unique among its ILK.
@ast
Integrin-linked kinase: a cancer therapeutic target unique among its ILK.
@en
type
label
Integrin-linked kinase: a cancer therapeutic target unique among its ILK.
@ast
Integrin-linked kinase: a cancer therapeutic target unique among its ILK.
@en
prefLabel
Integrin-linked kinase: a cancer therapeutic target unique among its ILK.
@ast
Integrin-linked kinase: a cancer therapeutic target unique among its ILK.
@en
P2093
P356
P1476
Integrin-linked kinase: a cancer therapeutic target unique among its ILK.
@en
P2093
Armelle A Troussard
Gregory Hannigan
Shoukat Dedhar
P2888
P356
10.1038/NRC1524
P407
P577
2005-01-01T00:00:00Z
P6179
1039192304