Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials - Wikidata - wikimedia - TriplyDB

Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials

Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials

http://www.wikidata.org/entity/Q35998823

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The possibility of clinical sequencing in the management of cancer Clinical Application of Targeted Next Generation Sequencing for Colorectal Cancers Facilitating a culture of responsible and effective sharing of cancer genome data CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer Implementing Genome-Driven Oncology.Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial.The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine.Giving Up on Precision Oncology? Not So Fast!Neutrophil count is associated with myeloid derived suppressor cell level and presents prognostic value of for hepatocellular carcinoma patients.Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors.Genomic mutation-driven metastatic breast cancer therapy: a single center experience Experience with precision genomics and tumor board, indicates frequent target identification, but barriers to delivery.Antiangiogenesis and gene aberration-related therapy may improve overall survival in patients with concurrent KRAS and TP53 hotspot mutant cancer Clinical sequencing using a next-generation sequencing-based multiplex gene assay in patients with advanced solid tumors.Clinical genomic profiling to identify actionable alterations for investigational therapies in patients with diverse sarcomas.Precision oncology: Charting a path forward to broader deployment of genomic profiling Precision Medicine for Molecularly Targeted Agents and Immunotherapies in Early-Phase Clinical Trials.Data resources for the identification and interpretation of actionable mutations by clinicians."Cancer 2015": A Prospective, Population-Based Cancer Cohort-Phase 1: Feasibility of Genomics-Guided Precision Medicine in the Clinic Clinical trial designs incorporating predictive biomarkers.Human lung adenocarcinoma cell cultures derived from malignant pleural effusions as model system to predict patients chemosensitivity The current use and attitudes towards tumor genome sequencing in breast cancer.Patient knowledge and information-seeking about personalized cancer therapy.Development and clinical application of an integrative genomic approach to personalized cancer therapy Non-invasive urine testing of EGFR activating mutation and T790M resistance mutation in non-small cell lung cancer.Precision Oncology Framework for Investigation of Exercise As Treatment for Cancer.Determination of somatic oncogenic mutations linked to target-based therapies using MassARRAY technology.The Conundrum of Genetic "Drivers" in Benign Conditions.Rational design of cancer gene panels with OncoPaD.Institutional implementation of clinical tumor profiling on an unselected cancer population.Molecular spectrum of KRAS, NRAS, BRAF, PIK3CA, TP53, and APC somatic gene mutations in Arab patients with colorectal cancer: determination of frequency and distribution pattern.Implementation of next generation sequencing into pediatric hematology-oncology practice: moving beyond actionable alterations.Clinical Actionability of Comprehensive Genomic Profiling for Management of Rare or Refractory Cancers.Biopsy-free circulating tumor DNA assay identifies actionable mutations in lung cancer.Massively parallel DNA sequencing from routinely processed cytological smears.Impact of tissue-based genomic profiling on clinical decision making in the management of patients with metastatic breast cancer at academic centers.A Software Application for Mining and Presenting Relevant Cancer Clinical Trials per Cancer Mutation.Cell-free circulating tumour DNA as a liquid biopsy in breast cancer.Modeling of Patient-Derived Xenografts in Colorectal Cancer.Key Lessons Learned from Moffitt's Molecular Tumor Board: The Clinical Genomics Action Committee Experience.

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Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials

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JCO.2014.60.4165

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Journal of Clinical Oncology

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Feasibility of Large-Scale Gen ...... ically Matched Clinical Trials

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Chacha Horombe

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David Hong

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Filip Janku

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Funda Meric-Bernstam

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Gordon B Mills

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John De Groot

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John Mendelsohn

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Kenna Shaw

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Keyur Patel

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Lauren Brusco

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P2860

Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials

Enabling a genetically informed approach to cancer medicine: a retrospective evaluation of the impact of comprehensive tumor profiling using a targeted next-generation sequencing panel

Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs.

Clinical validation of a next-generation sequencing screen for mutational hotspots in 46 cancer-related genes.

Concordance of genomic alterations between primary and recurrent breast cancer.

Physicians' attitudes about multiplex tumor genomic testing.

Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing.

Comparative genomic hybridisation array and DNA sequencing to direct treatment of metastatic breast cancer: a multicentre, prospective trial (SAFIR01/UNICANCER).

Clinical next-generation sequencing in patients with non-small cell lung cancer.

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2753-2762

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10.1200/JCO.2014.60.4165

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25

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33

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Sarina Piha-Paul

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2015-05-26T00:00:00Z

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26014291

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4550690

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