Transcription yield of fully 2'-modified RNA can be increased by the addition of thermostabilizing mutations to T7 RNA polymerase mutants.
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Modified Nucleoside Triphosphates for In-vitro Selection TechniquesFrom selection hits to clinical leads: progress in aptamer discoverySynthetic, Functional Thymidine-Derived Polydeoxyribonucleotide Analogues from a Six-Membered Cyclic Phosphoester.The Toolbox for Modified Aptamers.Post-ExSELEX stabilization of an unnatural-base DNA aptamer targeting VEGF165 toward pharmaceutical applications.The expanding world of DNA and RNA.Effect of Chemical Modifications on Aptamer Stability in Serum.A T7 RNA Polymerase Mutant Enhances the Yield of 5'-Thienoguanosine-Initiated RNAs.Evolved polymerases facilitate selection of fully 2'-OMe-modified aptamers.Genetic alphabet expansion transcription generating functional RNA molecules containing a five-letter alphabet including modified unnatural and natural base nucleotides by thermostable T7 RNA polymerase variants.Viral attenuation by engineered protein fragmentation.
P2860
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P2860
Transcription yield of fully 2'-modified RNA can be increased by the addition of thermostabilizing mutations to T7 RNA polymerase mutants.
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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name
Transcription yield of fully 2 ...... to T7 RNA polymerase mutants.
@ast
Transcription yield of fully 2 ...... to T7 RNA polymerase mutants.
@en
type
label
Transcription yield of fully 2 ...... to T7 RNA polymerase mutants.
@ast
Transcription yield of fully 2 ...... to T7 RNA polymerase mutants.
@en
prefLabel
Transcription yield of fully 2 ...... to T7 RNA polymerase mutants.
@ast
Transcription yield of fully 2 ...... to T7 RNA polymerase mutants.
@en
P2093
P2860
P356
P1476
Transcription yield of fully 2 ...... to T7 RNA polymerase mutants.
@en
P2093
Adam J Meyer
Andrew D Ellington
Bradley Hall
Daniel J Garry
Hannah G McDonald
Michelle M Byrom
Y Whitney Yin
P2860
P304
P356
10.1093/NAR/GKV734
P407
P577
2015-07-24T00:00:00Z