Promyelocytic leukemia zinc finger turns on the effector T cell program without requirement for agonist TCR signaling
about
Transcriptional regulation of the NKT cell lineageID'ing innate and innate-like lymphoid cellsElevated T cell receptor signaling identifies a thymic precursor to the TCRαβ(+)CD4(-)CD8β(-) intraepithelial lymphocyte lineage.Jarid2 is induced by TCR signalling and controls iNKT cell maturation.PLZF regulates CCR6 and is critical for the acquisition and maintenance of the Th17 phenotype in human cells.Zbtb16 (PLZF) is stably suppressed and not inducible in non-innate T cells via T cell receptor-mediated signaling.Making memory at birth: understanding the differentiation of natural killer T cellsPLZF Controls the Expression of a Limited Number of Genes Essential for NKT Cell Function.PLZF confers effector functions to donor T cells that preserve graft-versus-tumor effects while attenuating GVHDMultiple layers of transcriptional regulation by PLZF in NKT-cell developmentHallmarks of Tissue-Resident Lymphocytes.Forging T-Lymphocyte Identity: Intersecting Networks of Transcriptional Control.Concise Review: Balancing Stem Cell Self-Renewal and Differentiation with PLZF.A committed precursor to innate lymphoid cellsBTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling.Crossreactive αβ T Cell Receptors Are the Predominant Targets of Thymocyte Negative Selection.NKAP Regulates Invariant NKT Cell Proliferation and Differentiation into ROR-γt-Expressing NKT17 Cells.Essential functions for ID proteins at multiple checkpoints in invariant NKT cell development.A transgenic TCR directs the development of IL-4+ and PLZF+ innate CD4 T cells.PLZF Controls the Development of Fetal-Derived IL-17+Vγ6+ γδ T Cells.Histone Deacetylase 7 mediates tissue-specific autoimmunity via control of innate effector function in invariant Natural Killer T Cells.Insights Into Mucosal-Associated Invariant T Cell Biology From Studies of Invariant Natural Killer T Cells.PLZF play as an indirect facilitator of thymic retention for the innate-like T-cells to aquire innate-like functions
P2860
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P2860
Promyelocytic leukemia zinc finger turns on the effector T cell program without requirement for agonist TCR signaling
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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name
Promyelocytic leukemia zinc fi ...... ment for agonist TCR signaling
@ast
Promyelocytic leukemia zinc fi ...... ment for agonist TCR signaling
@en
type
label
Promyelocytic leukemia zinc fi ...... ment for agonist TCR signaling
@ast
Promyelocytic leukemia zinc fi ...... ment for agonist TCR signaling
@en
prefLabel
Promyelocytic leukemia zinc fi ...... ment for agonist TCR signaling
@ast
Promyelocytic leukemia zinc fi ...... ment for agonist TCR signaling
@en
P2093
P2860
P356
P1476
Promyelocytic leukemia zinc fi ...... ment for agonist TCR signaling
@en
P2093
Adam K Savage
Albert Bendelac
Michael G Constantinides
P2860
P304
P356
10.4049/JIMMUNOL.1100119
P407
P577
2011-04-08T00:00:00Z