Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liver.
about
Tissue engineering tools for modulation of the immune responseProgress and prospects: immune responses to viral vectorsSafety and efficacy of subretinal readministration of a viral vector in large animals to treat congenital blindnessRescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skippingWhole body correction of mucopolysaccharidosis IIIA by intracerebrospinal fluid gene therapyTranslational data from adeno-associated virus-mediated gene therapy of hemophilia B in dogsTolerance induction to cytoplasmic beta-galactosidase by hepatic AAV gene transfer: implications for antigen presentation and immunotoxicitySystemic myostatin inhibition via liver-targeted gene transfer in normal and dystrophic miceHost and vector-dependent effects on the risk of germline transmission of AAV vectors.Strategies to modulate immune responses: a new frontier for gene therapyHepatic gene transfer as a means of tolerance induction to transgene productsIntensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primatesPeripheral transvenular delivery of adeno-associated viral vectors to skeletal muscle as a novel therapy for hemophilia B.Cell-Mediated Immunity to AAV Vectors, Evolving Concepts and Potential Solutions.Safety of AAV factor IX peripheral transvenular gene delivery to muscle in hemophilia B dogs.In vitro and In vivo Model Systems for Hemophilia A Gene Therapy.Eradication of neutralizing antibodies to factor VIII in canine hemophilia A after liver gene therapy.RETRACTED: Activation of the NF-kappaB pathway by adeno-associated virus (AAV) vectors and its implications in immune response and gene therapyEfficacy and safety of long-term prophylaxis in severe hemophilia A dogs following liver gene therapy using AAV vectors.Pre-immunization with an intramuscular injection of AAV9-human erythropoietin vectors reduces the vector-mediated transduction following re-administration in rat brainDevelopment of Gene Transfer for Induction of Antigen-specific Tolerance.Portal vein delivery of viral vectors for gene therapy for hemophilia.Therapeutic approaches to muscular dystrophy.Long-term safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteins.Engineering biomaterial systems to enhance viral vector gene delivery.Systemic administration of AAV8-α-galactosidase A induces humoral tolerance in nonhuman primates despite low hepatic expressionLong-term systemic myostatin inhibition via liver-targeted gene transfer in golden retriever muscular dystrophy.Gene therapy for haemophilia: prospects and challenges to prevent or reverse inhibitor formation.Pharmacological modulation of humoral immunity in a nonhuman primate model of AAV gene transfer for hemophilia B.Transient and intensive pharmacological immunosuppression fails to improve AAV-based liver gene transfer in non-human primates.Successful attenuation of humoral immunity to viral capsid and transgenic protein following AAV-mediated gene transfer with a non-depleting CD4 antibody and cyclosporineImmune responses to adenovirus and adeno-associated vectors used for gene therapy of brain diseases: the role of immunological synapses in understanding the cell biology of neuroimmune interactionsHigh-capacity adenovirus vector-mediated anti-glioma gene therapy in the presence of systemic antiadenovirus immunity.Nonviral-mediated hepatic expression of IGF-I increases Treg levels and suppresses autoimmune diabetes in mice.Evading the immune response upon in vivo gene therapy with viral vectors.Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells.Transient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A miceInjection of vessel-derived stem cells prevents dilated cardiomyopathy and promotes angiogenesis and endogenous cardiac stem cell proliferation in mdx/utrn-/- but not aged mdx mouse models for duchenne muscular dystrophy.Enhanced T cell function in a mouse model of human glycosylation.Immune responses to AAV vectors: overcoming barriers to successful gene therapy
P2860
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P2860
Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liver.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Modulation of tolerance to the ...... diated gene transfer to liver.
@ast
Modulation of tolerance to the ...... diated gene transfer to liver.
@en
type
label
Modulation of tolerance to the ...... diated gene transfer to liver.
@ast
Modulation of tolerance to the ...... diated gene transfer to liver.
@en
prefLabel
Modulation of tolerance to the ...... diated gene transfer to liver.
@ast
Modulation of tolerance to the ...... diated gene transfer to liver.
@en
P2093
P2860
P1433
P1476
Modulation of tolerance to the ...... ediated gene transfer to liver
@en
P2093
Daniel J Hui
Denise E Sabatino
Etiena Basner-Tschakarjan
Federico Mingozzi
Glenn F Pierce
J Fraser Wright
Katherine A High
Nicole C Hasbrouck
Shangzhen Zhou
Shyrie A Edmonson
P2860
P304
P356
10.1182/BLOOD-2007-03-080093
P407
P50
P577
2007-07-03T00:00:00Z