A stereoselective synthesis of phosphinic acid phosphapeptides corresponding to glutamyl-gamma-glutamate and incorporation into potent inhibitors of folylpoly-gamma-glutamyl synthetase.
about
Synthetic and structural studies on syringolin A and B reveal critical determinants of selectivity and potency of proteasome inhibitionTotal synthesis of the hypermodified RNA bases wybutosine and hydroxywybutosine and their quantification together with other modified RNA bases in plant materials.Stereocontrolled total syntheses of isodomoic acids G and H via a unified strategy.Prodrug forms of N-[(4-deoxy-4-amino-10-methyl)pteroyl]glutamate-gamma-[psiP(O)(OH)]-glutarate, a potent inhibitor of folylpoly-gamma-glutamate synthetase: synthesis and hydrolytic stability.Regioselective synthesis of alpha-methyl 2-methyleneglutarate via a novel lactonization-elimination rearrangement.Alkylation of H-phosphinate esters under basic conditions.Borane Complexes of the H(3)PO(2) P(III) Tautomer: Useful Phosphinate Equivalents.Synthesis of isopeptide epoxide peptidomimetics.Inhibition of human folylpolyglutamate synthetase by diastereomeric phosphinic acid mimics of the tetrahedral intermediate.Total syntheses of isodomoic acids G and H.Design, synthesis, and biological evaluation of conformationally constrained glycerol 3-phosphate acyltransferase inhibitors.Aminophosphine Oxides: A Platform for Diversified Functions.General synthesis of P-stereogenic compounds: the menthyl phosphinate approach.Characterisation of the bifunctional dihydrofolate synthase-folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition.ATP-dependent ligases in trypanothione biosynthesis--kinetics of catalysis and inhibition by phosphinic acid pseudopeptides.A synthesis of oligomeric alpha-hydroxy phenylphosphinates and a study of the conformational preferences of the dimers.Continuous-flow thermolysis for the preparation of vinylglycine derivatives.
P2860
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P2860
A stereoselective synthesis of phosphinic acid phosphapeptides corresponding to glutamyl-gamma-glutamate and incorporation into potent inhibitors of folylpoly-gamma-glutamyl synthetase.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
A stereoselective synthesis of ...... oly-gamma-glutamyl synthetase.
@ast
A stereoselective synthesis of ...... oly-gamma-glutamyl synthetase.
@en
type
label
A stereoselective synthesis of ...... oly-gamma-glutamyl synthetase.
@ast
A stereoselective synthesis of ...... oly-gamma-glutamyl synthetase.
@en
prefLabel
A stereoselective synthesis of ...... oly-gamma-glutamyl synthetase.
@ast
A stereoselective synthesis of ...... oly-gamma-glutamyl synthetase.
@en
P2860
P356
P1476
A stereoselective synthesis of ...... oly-gamma-glutamyl synthetase.
@en
P2093
David M Bartley
James K Coward
P2860
P304
P356
10.1021/JO0507439
P407
P577
2005-08-01T00:00:00Z