Age-related defects in TLR2 signaling diminish the cytokine response by alveolar macrophages during murine pneumococcal pneumonia
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Age-dependent dysregulation of innate immunityCardiotoxicity during invasive pneumococcal diseaseInfluence of age, past smoking, and disease severity on TLR2, neutrophilic inflammation, and MMP-9 levels in COPDHost Factors and Biomarkers Associated with Poor Outcomes in Adults with Invasive Pneumococcal DiseaseInnate immune responses in the ageing lung.Peritoneal exudate cells from long-lived rats exhibit increased IL-10/IL-1β expression ratio and preserved NO/urea ratio following LPS-stimulation in vitroDonor age and early graft failure after lung transplantation: a cohort study.Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function.Requirement for Serratia marcescens cytolysin in a murine model of hemorrhagic pneumoniaEnhanced inflammation in aged mice following infection with Streptococcus pneumoniae is associated with decreased IL-10 and augmented chemokine production.Extracellular Adenosine Protects against Streptococcus pneumoniae Lung Infection by Regulating Pulmonary Neutrophil RecruitmentFlagellin-dependent TLR5/caveolin-1 as a promising immune activator in immunosenescence.Mechanisms of lung aging.Toll like receptor signaling in "inflammaging": microRNA as new players.The α-tocopherol form of vitamin E reverses age-associated susceptibility to streptococcus pneumoniae lung infection by modulating pulmonary neutrophil recruitment.Infiltrated Macrophages Die of Pneumolysin-Mediated Necroptosis following Pneumococcal Myocardial InvasionImpaired innate mucosal immunity in aged mice permits prolonged Streptococcus pneumoniae colonization.Aged mice are unable to mount an effective myeloid response to sepsis.Protective immunity and defects in the neonatal and elderly immune response to sepsisElevated A20 contributes to age-dependent macrophage dysfunction in the lungs.Aging oppositely affects TNF-α and IL-10 production by macrophages from different rat strains.Immunosenescence in monocytes, macrophages, and dendritic cells: lessons learned from the lung and heart.Immune ageing and susceptibility to Streptococcus pneumoniae.Advanced Age Alters Monocyte and Macrophage Responses.Aging Impairs Alveolar Macrophage Phagocytosis and Increases Influenza-Induced Mortality in Mice.Inflammaging and the Lung.Contribution of host, bacterial factors and antibiotic treatment to mortality in adult patients with bacteraemic pneumococcal pneumonia.COMMUNITY ACQUIRED PNEUMOCOCCAL PNEUMONIA IN NORTHWESTERN NIGERIA: EPIDEMIOLOGY, ANTIMICROBIAL RESISTANCE AND OUTCOME.NLRP3 Inflammasome Activation in Aged Macrophages is diminished during Streptococcus pneumoniae Infection.Decreased NLRP3 inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection.Bacterial Adherence and Dwelling Probability: Two Drivers of Early Alveolar Infection by Streptococcus pneumoniae Identified in Multi-Level Mathematical Modeling.Streptococcus pneumoniae’s Virulence and Host Immunity: Aging, Diagnostics, and Prevention.Age does not influence the disease course in a mouse model of serotype 3 meningitis
P2860
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P2860
Age-related defects in TLR2 signaling diminish the cytokine response by alveolar macrophages during murine pneumococcal pneumonia
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Age-related defects in TLR2 si ...... murine pneumococcal pneumonia
@ast
Age-related defects in TLR2 si ...... murine pneumococcal pneumonia
@en
type
label
Age-related defects in TLR2 si ...... murine pneumococcal pneumonia
@ast
Age-related defects in TLR2 si ...... murine pneumococcal pneumonia
@en
prefLabel
Age-related defects in TLR2 si ...... murine pneumococcal pneumonia
@ast
Age-related defects in TLR2 si ...... murine pneumococcal pneumonia
@en
P2093
P2860
P921
P1476
Age-related defects in TLR2 si ...... murine pneumococcal pneumonia
@en
P2093
Angela R Boyd
Carlos J Orihuela
Michael T Berton
Pooja Shivshankar
Shoulei Jiang
P2860
P304
P356
10.1016/J.EXGER.2012.04.004
P577
2012-04-23T00:00:00Z