Secretion of a lysophospholipase D activity by adipocytes: involvement in lysophosphatidic acid synthesis
about
Potential involvement of adipocyte insulin resistance in obesity-associated up-regulation of adipocyte lysophospholipase D/autotaxin expressionAdipose-specific disruption of autotaxin enhances nutritional fattening and reduces plasma lysophosphatidic acid.Serum autotaxin is independently associated with hepatic steatosis in women with severe obesity.Production of lysophosphatidic acid in blister fluid: involvement of a lysophospholipase D activityAutotaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation. Up-regulated expression with adipocyte differentiation and obesitySerum Autotaxin/ENPP2 correlates with insulin resistance in older humans with obesity.Age-dependent loss of sperm production in mice via impaired lysophosphatidic acid signaling.Lysophosphatidic acid (LPA) as a pro-fibrotic and pro-oncogenic factor: a pivotal target to improve the radiotherapy therapeutic index.Expression of factors involved in apoptosis and cell survival is correlated with enzymes synthesizing lysophosphatidic acid and its receptors in granulosa cells originating from different types of bovine ovarian follicles.Blocking gp130 signaling suppresses autotaxin expression in adipocytes and improves insulin sensitivity in diet-induced obesity.Lipid phosphate phosphatase 3 regulates adipocyte sphingolipid synthesis, but not developmental adipogenesis or diet-induced obesity in mice.Production of extracellular lysophosphatidic acid in the regulation of adipocyte functions and liver fibrosis
P2860
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P2860
Secretion of a lysophospholipase D activity by adipocytes: involvement in lysophosphatidic acid synthesis
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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name
Secretion of a lysophospholipa ...... ysophosphatidic acid synthesis
@ast
Secretion of a lysophospholipa ...... ysophosphatidic acid synthesis
@en
type
label
Secretion of a lysophospholipa ...... ysophosphatidic acid synthesis
@ast
Secretion of a lysophospholipa ...... ysophosphatidic acid synthesis
@en
prefLabel
Secretion of a lysophospholipa ...... ysophosphatidic acid synthesis
@ast
Secretion of a lysophospholipa ...... ysophosphatidic acid synthesis
@en
P2093
P2860
P1476
Secretion of a lysophospholipa ...... ysophosphatidic acid synthesis
@en
P2093
Alexia Girard
Astrid Rey
David Sibrac
Jean Sébastien Saulnier-Blache
Marie-Françoise Simon
Max Lafontan
Philippe Valet
Stéphane Gesta
P2860
P304
P577
2002-06-01T00:00:00Z