Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate.
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Wnt signaling networks in autism spectrum disorder and intellectual disabilityDisrupted-in-Schizophrenia-1 is essential for normal hypothalamic-pituitary-interrenal (HPI) axis function.Modeling developmental neuropsychiatric disorders with iPSC technology: challenges and opportunitiesConcise Review: Progress and Challenges in Using Human Stem Cells for Biological and Therapeutics Discovery: Neuropsychiatric Disorders.Modeling psychiatric disorders: from genomic findings to cellular phenotypesRecent Advances in CRISPR-Cas9 Genome Editing Technology for Biological and Biomedical Investigations.Modeling psychiatric disorders with patient-derived iPSCs.How Wnt Signaling Builds the Brain: Bridging Development and Disease.Common developmental genome deprogramming in schizophrenia - Role of Integrative Nuclear FGFR1 Signaling (INFS).Molecular mechanisms underlying noncoding risk variations in psychiatric genetic studiesPluripotent stem cells in neuropsychiatric disorders.Application of CRISPR/Cas9 to the study of brain development and neuropsychiatric disease.Modeling schizophrenia pathogenesis using patient-derived induced pluripotent stem cells (iPSCs).Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer.Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes.A Scaled Framework for CRISPR Editing of Human Pluripotent Stem Cells to Study Psychiatric Disease.A prenatal interruption of DISC1 function in the brain exhibits a lasting impact on adult behaviors, brain metabolism, and interneuron development.iPhemap: an atlas of phenotype to genotype relationships of human iPSC models of neurological diseases.Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains.Personalized medicine in a dish: the growing possibility of neuropsychiatric disease drug discovery tailored to patient genetic variants using stem cells.Overexpression of Truncated Human DISC1 Induces Appearance of Hindbrain Oligodendroglia in the Forebrain During Development.Understanding neurodevelopmental disorders using human pluripotent stem cell-derived neurons.Genome-editing applications of CRISPR-Cas9 to promote in vitro studies of Alzheimer's disease.Using mouse transgenic and human stem cell technologies to model genetic mutations associated with schizophrenia and autism.New considerations for hiPSC-based models of neuropsychiatric disorders.Modeling Neuropsychiatric and Neurodegenerative Diseases With Induced Pluripotent Stem Cells.Shared effects of DISC1 disruption and elevated WNT signaling in human cerebral organoids.Control of CNS functions by RNA-binding proteins in neurological diseasesConvergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expressionDISC1 regulates N-methyl-D-aspartate receptor dynamics: abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illnessRecapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation
P2860
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P2860
Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate.
@ast
Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate.
@en
type
label
Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate.
@ast
Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate.
@en
prefLabel
Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate.
@ast
Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate.
@en
P2093
P2860
P4510
P50
P1433
P1476
Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate.
@en
P2093
Christina R Muratore
Dennis J Selkoe
Eugenia Makovkina
Justin D Boyd
Kenneth S Kosik
Tracy L Young-Pearse
P2860
P304
P356
10.1016/J.CELREP.2015.07.061
P577
2015-08-19T00:00:00Z