The coordination of cyclic microtubule association/dissociation and tail swing of cytoplasmic dynein
about
ATP-driven remodeling of the linker domain in the dynein motorReview: Structure and mechanism of the dynein motor ATPaseCiliobrevins as tools for studying dynein motor functionThe 2.8 Å crystal structure of the dynein motor domainInsights into dynein motor domain function from a 3.3-Å crystal structureThe yeast dynein Dyn2-Pac11 complex is a dynein dimerization/processivity factor: structural and single-molecule characterizationLis1 acts as a "clutch" between the ATPase and microtubule-binding domains of the dynein motor.Lis1 regulates dynein by sterically blocking its mechanochemical cycle.Cytoplasmic dynein regulates its attachment to microtubules via nucleotide state-switched mechanosensing at multiple AAA domains.Arp11 affects dynein-dynactin interaction and is essential for dynein function in Aspergillus nidulans.Functions and mechanics of dynein motor proteinsMechanical dynamics in live cells and fluorescence-based force/tension sensorsDynein pulls microtubules without rotating its stalkLIS1 and NudE induce a persistent dynein force-producing stateReconstitution of the human cytoplasmic dynein complex.A mouse neurodegenerative dynein heavy chain mutation alters dynein motility and localization in Neurospora crassa.Cytoplasmic dynein moves through uncoordinated stepping of the AAA+ ring domainsThe AAA3 domain of cytoplasmic dynein acts as a switch to facilitate microtubule release.Direct observation shows superposition and large scale flexibility within cytoplasmic dynein motors moving along microtubules.Communication between the AAA+ ring and microtubule-binding domain of dynein.A physical model reveals the mechanochemistry responsible for dynein's processive motion.Cytoplasmic dynein transports cargos via load-sharing between the heads.Analyses of dynein heavy chain mutations reveal complex interactions between dynein motor domains and cellular dynein functions.Molecular motors: not quite like clockworkHelix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding.A microscopy-based screen employing multiplex genome sequencing identifies cargo-specific requirements for dynein velocity.Molecular organization and force-generating mechanism of dynein.The mechanism of dynein motility: insight from crystal structures of the motor domainBig steps toward understanding dynein.Microtubule Motors Drive Hedgehog Signaling in Primary Cilia.Coarse-grained modeling of the structural states and transition underlying the powerstroke of dynein motor domain.Peptides mediating DNA Transport on microtubules and their impact on non-viral gene transfer efficiency.Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action.Structure of human cytoplasmic dynein-2 primed for its power stroke.AAA+ Ring and linker swing mechanism in the dynein motor.Tension on the linker gates the ATP-dependent release of dynein from microtubulesAllosteric conformational change cascade in cytoplasmic dynein revealed by structure-based molecular simulations.Minimum requirements for motility of a processive motor protein.The winch model can explain both coordinated and uncoordinated stepping of cytoplasmic dynein.Nucleotide-dependent behavior of single molecules of cytoplasmic dynein on microtubules in vitro.
P2860
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P2860
The coordination of cyclic microtubule association/dissociation and tail swing of cytoplasmic dynein
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The coordination of cyclic mic ...... il swing of cytoplasmic dynein
@ast
The coordination of cyclic mic ...... il swing of cytoplasmic dynein
@en
type
label
The coordination of cyclic mic ...... il swing of cytoplasmic dynein
@ast
The coordination of cyclic mic ...... il swing of cytoplasmic dynein
@en
prefLabel
The coordination of cyclic mic ...... il swing of cytoplasmic dynein
@ast
The coordination of cyclic mic ...... il swing of cytoplasmic dynein
@en
P2093
P2860
P356
P1476
The coordination of cyclic mic ...... il swing of cytoplasmic dynein
@en
P2093
Kazuo Sutoh
Kenji Imamula
Reiko Ohkura
P2860
P304
16134-16139
P356
10.1073/PNAS.0702370104
P407
P50
P577
2007-10-02T00:00:00Z