The anaphase-promoting complex: a key factor in the regulation of cell cycle.
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Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosisEmi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitorUbiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/CTwo different mitotic checkpoint inhibitors of the anaphase-promoting complex/cyclosome antagonize the action of the activator Cdc20Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progressionMaintaining Genome Stability in Defiance of Mitotic DNA DamageParkin Regulates Mitosis and Genomic Stability through Cdc20/Cdh1.Inactivation of Cdh1 by synergistic action of Cdk1 and polo kinase is necessary for proper assembly of the mitotic spindle.Cdk1 regulates centrosome separation by restraining proteolysis of microtubule-associated proteinsThe DNA damage response mediator MDC1 directly interacts with the anaphase-promoting complex/cyclosomeThe ubiquitin proteasome system and myocardial ischemiaUbiquitin and SUMO systems in the regulation of mitotic checkpointsMouse emi1 has an essential function in mitotic progression during early embryogenesisEmi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/CFunction of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradationHeterogeneity of mammary lesions represent molecular differencesA test of highly optimized tolerance reveals fragile cell-cycle mechanisms are molecular targets in clinical cancer trialsRSS1 regulates the cell cycle and maintains meristematic activity under stress conditions in rice.The ubiquitin-proteasome system in myocardial ischaemia and preconditioning.p62 links the autophagy pathway and the ubiqutin-proteasome system upon ubiquitinated protein degradationIdentification of nitric oxide as an endogenous inhibitor of 26S proteasomes in vascular endothelial cells.Protein phosphatase 2A regulatory subunit B55α functions in mouse oocyte maturation and early embryonic development.Aberrant cell cycle and apoptotic changes characterise severe influenza A infection--a meta-analysis of genomic signatures in circulating leukocytes.Cytoplasmic dynein's mitotic spindle pole localization requires a functional anaphase-promoting complex, gamma-tubulin, and NUDF/LIS1 in Aspergillus nidulans.Time-resolved human kinome RNAi screen identifies a network regulating mitotic-events as early regulators of cell proliferation.Accumulation of substrates of the anaphase-promoting complex (APC) during human cytomegalovirus infection is associated with the phosphorylation of Cdh1 and the dissociation and relocalization of APC subunits.Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation.Transcriptional profiling of bovine milk using RNA sequencingPhosphatase 1 nuclear targeting subunit is an essential regulator of M-phase entry, maintenance, and exitAttributes of short linear motifs.Degradation of the human mitotic checkpoint kinase Mps1 is cell cycle-regulated by APC-cCdc20 and APC-cCdh1 ubiquitin ligases.Regulation of the proteasome by AMPK in endothelial cells: the role of O-GlcNAc transferase (OGT).LRpath analysis reveals common pathways dysregulated via DNA methylation across cancer typesRoles of the anaphase-promoting complex/cyclosome and of its activator Cdc20 in functional substrate binding.Predicting binding within disordered protein regions to structurally characterised peptide-binding domains.Modeling dual pathways for the metazoan spindle assembly checkpoint.Impaired Cell Cycle Regulation in a Natural Equine Model of Asthma.The ubiquitin-proteasome system as a prospective molecular target for cancer treatment and prevention.Heritable epigenetic mutation of a transposon-flanked Arabidopsis gene due to lack of the chromatin-remodeling factor DDM1.
P2860
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P2860
The anaphase-promoting complex: a key factor in the regulation of cell cycle.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
The anaphase-promoting complex: a key factor in the regulation of cell cycle.
@ast
The anaphase-promoting complex: a key factor in the regulation of cell cycle.
@en
type
label
The anaphase-promoting complex: a key factor in the regulation of cell cycle.
@ast
The anaphase-promoting complex: a key factor in the regulation of cell cycle.
@en
prefLabel
The anaphase-promoting complex: a key factor in the regulation of cell cycle.
@ast
The anaphase-promoting complex: a key factor in the regulation of cell cycle.
@en
P2093
P2860
P356
P1433
P1476
The anaphase-promoting complex: a key factor in the regulation of cell cycle.
@en
P2093
Anna Castro
Cyril Bernis
Jean-Claude Labbé
Suzanne Vigneron
Thierry Lorca
P2860
P2888
P304
P356
10.1038/SJ.ONC.1207973
P407
P577
2005-01-01T00:00:00Z