The anaphase-promoting complex: a key factor in the regulation of cell cycle. - Wikidata - wikimedia - TriplyDB

The anaphase-promoting complex: a key factor in the regulation of cell cycle.

The anaphase-promoting complex: a key factor in the regulation of cell cycle.

http://www.wikidata.org/entity/Q36022931

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Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1 Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C Two different mitotic checkpoint inhibitors of the anaphase-promoting complex/cyclosome antagonize the action of the activator Cdc20 Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression Maintaining Genome Stability in Defiance of Mitotic DNA Damage Parkin Regulates Mitosis and Genomic Stability through Cdc20/Cdh1.Inactivation of Cdh1 by synergistic action of Cdk1 and polo kinase is necessary for proper assembly of the mitotic spindle.Cdk1 regulates centrosome separation by restraining proteolysis of microtubule-associated proteins The DNA damage response mediator MDC1 directly interacts with the anaphase-promoting complex/cyclosome The ubiquitin proteasome system and myocardial ischemia Ubiquitin and SUMO systems in the regulation of mitotic checkpoints Mouse emi1 has an essential function in mitotic progression during early embryogenesis Emi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/C Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradation Heterogeneity of mammary lesions represent molecular differences A test of highly optimized tolerance reveals fragile cell-cycle mechanisms are molecular targets in clinical cancer trials RSS1 regulates the cell cycle and maintains meristematic activity under stress conditions in rice.The ubiquitin-proteasome system in myocardial ischaemia and preconditioning.p62 links the autophagy pathway and the ubiqutin-proteasome system upon ubiquitinated protein degradation Identification of nitric oxide as an endogenous inhibitor of 26S proteasomes in vascular endothelial cells.Protein phosphatase 2A regulatory subunit B55α functions in mouse oocyte maturation and early embryonic development.Aberrant cell cycle and apoptotic changes characterise severe influenza A infection--a meta-analysis of genomic signatures in circulating leukocytes.Cytoplasmic dynein's mitotic spindle pole localization requires a functional anaphase-promoting complex, gamma-tubulin, and NUDF/LIS1 in Aspergillus nidulans.Time-resolved human kinome RNAi screen identifies a network regulating mitotic-events as early regulators of cell proliferation.Accumulation of substrates of the anaphase-promoting complex (APC) during human cytomegalovirus infection is associated with the phosphorylation of Cdh1 and the dissociation and relocalization of APC subunits.Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation.Transcriptional profiling of bovine milk using RNA sequencing Phosphatase 1 nuclear targeting subunit is an essential regulator of M-phase entry, maintenance, and exit Attributes of short linear motifs.Degradation of the human mitotic checkpoint kinase Mps1 is cell cycle-regulated by APC-cCdc20 and APC-cCdh1 ubiquitin ligases.Regulation of the proteasome by AMPK in endothelial cells: the role of O-GlcNAc transferase (OGT).LRpath analysis reveals common pathways dysregulated via DNA methylation across cancer types Roles of the anaphase-promoting complex/cyclosome and of its activator Cdc20 in functional substrate binding.Predicting binding within disordered protein regions to structurally characterised peptide-binding domains.Modeling dual pathways for the metazoan spindle assembly checkpoint.Impaired Cell Cycle Regulation in a Natural Equine Model of Asthma.The ubiquitin-proteasome system as a prospective molecular target for cancer treatment and prevention.Heritable epigenetic mutation of a transposon-flanked Arabidopsis gene due to lack of the chromatin-remodeling factor DDM1.

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P2860

The anaphase-promoting complex: a key factor in the regulation of cell cycle.

http://www.wikidata.org/entity/Q36022931

description

2005 nî lūn-bûn

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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2005年论文

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2005年论文

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The anaphase-promoting complex: a key factor in the regulation of cell cycle.

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The anaphase-promoting complex: a key factor in the regulation of cell cycle.

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The anaphase-promoting complex: a key factor in the regulation of cell cycle.

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The anaphase-promoting complex: a key factor in the regulation of cell cycle.

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Anna Castro

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Cyril Bernis

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Jean-Claude Labbé

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Suzanne Vigneron

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Thierry Lorca

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P2860

Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex

The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex

Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1

APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex

E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)

Mitotic regulation of the human anaphase-promoting complex by phosphorylation

Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase

The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex

Geminin, an inhibitor of DNA replication, is degraded during mitosis

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

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314-325

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scholarly article

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10.1038/SJ.ONC.1207973

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3

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24

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8054227

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15678131

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