Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons.
about
The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsAttenuation of morphine withdrawal signs, blood cortisol and glucose level with forced exercise in comparison with clonidineNADPH-oxidase 2 activation promotes opioid-induced antinociceptive tolerance in mice.Opioid-induced mitogen-activated protein kinase signaling in rat enteric neurons following chronic morphine treatment.Identification of phosphorylation sites in the COOH-terminal tail of the μ-opioid receptorOpioid receptor desensitization: mechanisms and its link to toleranceCellular signalling of non-synonymous single-nucleotide polymorphisms of the human μ-opioid receptor (OPRM1)Recent advances on the δ opioid receptor: from trafficking to function.Association of OPRM1 A118G variant with risk of morphine-induced respiratory depression following spine fusion in adolescents.Downregulation of Spinal G Protein-Coupled Kinase 2 Abolished the Antiallodynic Effect of ElectroacupunctureDesensitization and trafficking of μ-opioid receptors in locus ceruleus neurons: modulation by kinases.GRK2 protein-mediated transphosphorylation contributes to loss of function of μ-opioid receptors induced by neuropeptide FF (NPFF2) receptors.Receptor Reserve Moderates Mesolimbic Responses to Opioids in a Humanized Mouse Model of the OPRM1 A118G PolymorphismAgonist Binding and Desensitization of the μ-Opioid Receptor Is Modulated by Phosphorylation of the C-Terminal Tail Domain.Morphine desensitization and cellular tolerance are distinguished in rat locus ceruleus neurons.μ-Opioid receptor desensitization: homologous or heterologous?Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.Agonist-Specific Recruitment of Arrestin Isoforms Differentially Modify Delta Opioid Receptor FunctionDual effect of morphine in long-term social memory in rat.Ligand-induced μ opioid receptor internalization in enteric neurons following chronic treatment with the opiate fentanylMolecular mechanisms of opioid receptor-dependent signaling and behavior.Increased agonist affinity at the μ-opioid receptor induced by prolonged agonist exposure.Learning-related translocation of δ-opioid receptors on ventral striatal cholinergic interneurons mediates choice between goal-directed actionsEndocytic profiles of δ-opioid receptor ligands determine the duration of rapid but not sustained cAMP responses.Analgesic tolerance of opioid agonists in mutant mu-opioid receptors expressed in sensory neurons following intrathecal plasmid gene delivery.Multifactorial Regulation of G Protein-Coupled Receptor Endocytosis.Morphine-induced trafficking of a mu-opioid receptor interacting protein in rat locus coeruleus neurons.Mechanistic models enable the rational use of in vitro drug-target binding kinetics for better drug effects in patients.Endogenous opioid system: a promising target for future smoking cessation medications.Genetic variation in the behavioral effects of buprenorphine in female mice derived from a murine model of the OPRM1 A118G polymorphism.Effect of apelin on the cardiac hemodynamics in hypertensive rats with heart failure.Enhancement of morphine analgesia and prevention of morphine tolerance by downregulation of β-arrestin 2 with antigene RNAs in mice.Central HIV-1 Tat exposure elevates anxiety and fear conditioned responses of male mice concurrent with altered mu-opioid receptor-mediated G-protein activation and β-arrestin 2 activity in the forebrain.Delta Opioid Receptor Expression and Function in Primary Afferent Somatosensory Neurons.Themed section: molecular pharmacology of GPCRs.Opioid-related (ORL1) receptors are enriched in a subpopulation of sensory neurons and prolonged activation produces no functional loss of surface N-type calcium channels.A real-time, fluorescence-based assay for measuring μ-opioid receptor modulation of adenylyl cyclase activity in Chinese hamster ovary cells.Why do patients stay in opioid maintenance treatment?Involvement of neuronal nitric oxide synthase in desensitisation of µ-opioid receptors in the rat locus coeruleus.Characterization of functional μ opioid receptor turnover in rat locus coeruleus: an electrophysiological and immunocytochemical study.
P2860
Q30486707-54AEAD82-BB3B-42A1-B854-7AC69017996FQ34197129-1E41D040-7582-4291-BF16-A08FB1A4E0D1Q34285878-B590FD16-6654-41AC-BD8C-AAA8D4FE4702Q34323667-A06603C6-BC3D-40EE-BB6C-012A1D459876Q34482298-95A89550-0283-4098-8770-543025E1BEA3Q34729984-C8D6C4DE-BCCF-4166-BDD1-BE43C2AD69C8Q34939590-F064C3EF-3BA1-4DC4-B763-E976C33FF201Q34939664-3BC4525D-23BB-42CD-B789-A9F23B84DA5DQ35528692-6EDBB0D3-20FC-4CE0-A23C-1275A627EDCAQ35598841-9E8A2757-851F-473F-BEEB-739483C61D2EQ35776772-41C16075-6ACC-4A39-A3C0-5FD5C87B52E2Q35921655-D2DD08BD-E35C-438C-92BA-7A41AC35FC4BQ36059914-8CD4271C-22AA-4316-98CD-6BC0FDE29919Q36077748-3834FB03-311C-44F3-AD7A-58F395E339C0Q36335620-FEEEAA97-C7FC-4290-8BA4-ADECEA00EA29Q36481130-559CAD20-16B5-4565-A5FA-161C9089C405Q36591603-03F60E0F-C6F4-4ABB-B829-29D7F6E50D6CQ36718661-BDA4C477-FADA-4211-926A-C0FF54A8BE58Q36756982-F3F505C8-649B-447B-82E9-545EF4260294Q36780862-58B71DCD-7FA5-492F-AECD-78754A657D47Q36974487-5FA5097C-150A-4869-8C35-1CA4A95CDE5AQ37014120-EC81B8EF-CC24-4BE4-B8ED-870832153C9BQ37220046-D67DB7F2-0E9F-4B50-A0F1-276065C52149Q37405423-20FAE992-8826-4259-93E6-6E8024146732Q37532600-DD23CD4F-77E7-47F4-9A40-E803A35419F0Q37551913-E01D8D29-9651-4D21-B0F5-445BD553AE6EQ37592198-04FACE90-B263-4C8A-9235-8E2DCD040534Q38611990-628BE3C8-92D5-4CA6-B7C6-149243FAA892Q38747115-87CC9815-7604-45B9-9292-7F78B71C759FQ38966273-3925AD54-87F6-430D-BFAF-1DFF0C7B262EQ41945177-4D73C821-C6F6-4D89-9030-011CD2663260Q42236094-008A2033-7D46-4E72-BF89-AFDE35471A28Q42715611-2CE8C69B-BBE6-41EF-9389-53FE6A41C322Q43075846-CF694826-C8A5-49F5-8C13-066A7403A4E9Q43196051-1777DA94-691C-4648-BB93-A5D5F1BFE4D7Q44333125-62B04D53-03F1-4BAF-9BD1-14354368EEAFQ44340996-A633CAFC-DA73-4554-9D8A-D93E1007331CQ44342483-93A79597-63EF-422D-8ABF-9AE919D83D76Q44345561-A3643BC3-CF2E-4877-BEB7-0905A92AD324Q44346280-5F4FA1BA-C7A6-4B4F-BB4A-D8F96B263F1D
P2860
Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Mechanisms of rapid opioid rec ...... nd tolerance in brain neurons.
@ast
Mechanisms of rapid opioid rec ...... nd tolerance in brain neurons.
@en
type
label
Mechanisms of rapid opioid rec ...... nd tolerance in brain neurons.
@ast
Mechanisms of rapid opioid rec ...... nd tolerance in brain neurons.
@en
prefLabel
Mechanisms of rapid opioid rec ...... nd tolerance in brain neurons.
@ast
Mechanisms of rapid opioid rec ...... nd tolerance in brain neurons.
@en
P2860
P1476
Mechanisms of rapid opioid rec ...... nd tolerance in brain neurons.
@en
P2093
MacDonald J Christie
P2860
P304
P356
10.1111/J.1476-5381.2011.01482.X
P407
P577
2012-03-01T00:00:00Z