Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function.
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The Structure of Carbonic Anhydrase IX Is Adapted for Low-pH CatalysisWortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cellsRoles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment.Metabolic Effect of Estrogen Receptor Agonists on Breast Cancer Cells in the Presence or Absence of Carbonic Anhydrase Inhibitors.Clinically relevant HIF-1α-dependent metabolic reprogramming in oropharyngeal squamous cell carcinomas includes coordinated activation of CAIX and the miR-210/ISCU signaling axis, but not MCT1 and MCT4 upregulation.Tumor-like microenvironment in oral lichen planus: evidence of malignant transformation?Selective inhibition of human carbonic anhydrase IX in Xenopus oocytes and MDA-MB-231 breast cancer cells.Catalytic activity of human carbonic anhydrase isoform IX is displayed both extra- and intracellularly.Hyperpolarized 13C Diffusion MRS of Co-Polarized Pyruvate and Fumarate to Measure Lactate Export and Necrosis.Downregulation of carbonic anhydrase IV contributes to promotion of cell proliferation and is associated with poor prognosis in non-small cell lung cancer.Branched-chain ketoacids secreted by glioblastoma cells via MCT1 modulate macrophage phenotype.Tumour acidosis: from the passenger to the driver's seat.Bicarbonate Recycling by HIF-1-Dependent Carbonic Anhydrase Isoforms 9 and 12 Is Critical in Maintaining Intracellular pH and Viability of Nucleus Pulposus Cells.Carbonic Anhydrase IX (CAIX), Cancer, and Radiation Responsiveness.Lactic Acid: No Longer an Inert and End-Product of Glycolysis.Microfluidic Encapsulation of Prickly Zinc-Doped Copper Oxide Nanoparticles with VD1142 Modified Spermine Acetalated Dextran for Efficient Cancer Therapy.Coordinated Regulation of Metabolic Transporters and Migration/Invasion by Carbonic Anhydrase IX.Recent advances in cancer metabolism: a technological perspective.Carbonic Anhydrases: Role in pH Control and Cancer.Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells.Cluster of differentiation 147 mediates chemoresistance in breast cancer by affecting vacuolar H+-ATPase expression and activity.A surface proton antenna in carbonic anhydrase II supports lactate transport in cancer cells.The proteoglycan-like domain of carbonic anhydrase IX mediates non-catalytic facilitation of lactate transport in cancer cells.
P2860
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P2860
Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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name
Hypoxia-induced carbonic anhyd ...... lls by non-catalytic function.
@ast
Hypoxia-induced carbonic anhyd ...... lls by non-catalytic function.
@en
type
label
Hypoxia-induced carbonic anhyd ...... lls by non-catalytic function.
@ast
Hypoxia-induced carbonic anhyd ...... lls by non-catalytic function.
@en
prefLabel
Hypoxia-induced carbonic anhyd ...... lls by non-catalytic function.
@ast
Hypoxia-induced carbonic anhyd ...... lls by non-catalytic function.
@en
P2093
P2860
P356
P1433
P1476
Hypoxia-induced carbonic anhyd ...... lls by non-catalytic function.
@en
P2093
Holger M Becker
Joachim W Deitmer
L Felipe Barros
Michael Klier
Robert McKenna
Samantha Ames
Somayeh Jamali
P2860
P2888
P356
10.1038/SREP13605
P407
P577
2015-09-04T00:00:00Z