Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo

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RCAN1-4 is a thyroid cancer growth and metastasis suppressor.PTEN controls glandular morphogenesis through a juxtamembrane β-Arrestin1/ARHGAP21 scaffolding complex Genetic ablation of interacting with Spt6 (Iws1) causes early embryonic lethality Regulation of PTEN expression by noncoding RNAs

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P2860

Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo

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http://www.wikidata.org/entity/Q36032452

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2015年の論文

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2015年論文

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Noncatalytic PTEN missense mut ...... ive cancer development in vivo

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Noncatalytic PTEN missense mut ...... ive cancer development in vivo

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Item

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Noncatalytic PTEN missense mut ...... ive cancer development in vivo

@ast

Noncatalytic PTEN missense mut ...... ive cancer development in vivo

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Noncatalytic PTEN missense mut ...... ive cancer development in vivo

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Noncatalytic PTEN missense mut ...... ive cancer development in vivo

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P1476

Noncatalytic PTEN missense mut ...... ive cancer development in vivo

@en

P2093

Adrian A Suarez

http://www.w3.org/2001/XMLSchema#string

Arunima Srivastava

http://www.w3.org/2001/XMLSchema#string

Charles L Shapiro

http://www.w3.org/2001/XMLSchema#string

Chelsea Martin

http://www.w3.org/2001/XMLSchema#string

Christopher Koivisto

http://www.w3.org/2001/XMLSchema#string

Cynthia Timmers

http://www.w3.org/2001/XMLSchema#string

David M O'Malley

http://www.w3.org/2001/XMLSchema#string

Diego H Castrillon

http://www.w3.org/2001/XMLSchema#string

Enrico Caserta

http://www.w3.org/2001/XMLSchema#string

Erin R Macrae

http://www.w3.org/2001/XMLSchema#string

P2860

The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region

Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase

Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2

Phosphorylation of the PTEN tail regulates protein stability and function

The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation

Ubiquitination regulates PTEN nuclear import and tumor suppression

Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner

Critical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformation

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1707-1720

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scholarly article

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10.1101/GAD.262568.115

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281214504

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Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo

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P2860

P2860

Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932