A reversible early oxidized redox state that precedes macromolecular ROS damage in aging nontransgenic and 3xTg-AD mouse neurons
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Efficient uptake and dissemination of scrapie prion protein by astrocytes and fibroblasts from adult hamster brainNicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession.Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS).Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.Relative importance of redox buffers GSH and NAD(P)H in age-related neurodegeneration and Alzheimer disease-like mouse neurons.Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer's disease-relevant murine model.Age-related metabolic fatigue during low glucose conditions in rat hippocampus.Age-related changes in neuroactive steroid levels in 3xTg-AD mice.Amyloid-β Peptide Aβ3pE-42 Induces Lipid Peroxidation, Membrane Permeabilization, and Calcium Influx in Neurons.β amyloid peptide plaques fail to alter evoked neuronal calcium signals in APP/PS1 Alzheimer's disease miceLinking redox regulation of NMDAR synaptic function to cognitive decline during aging.Glutathione maintenance mitigates age-related susceptibility to redox cycling agents.Melatonin and abeta, macular degeneration and alzheimers disease: same disease, different outcomes?Lack of association between nuclear factor erythroid-derived 2-like 2 promoter gene polymorphisms and oxidative stress biomarkers in amyotrophic lateral sclerosis patients.Antioxidant gene therapy against neuronal cell death.Role of antioxidant enzymes in redox regulation of N-methyl-D-aspartate receptor function and memory in middle-aged rats.Redox Signaling in Neurotransmission and Cognition During Aging.Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.Oxidative Modification and Its Implications for the Neurodegeneration of Parkinson's Disease.Vitamin D, reactive oxygen species and calcium signalling in ageing and disease.Lenti-GDNF gene therapy protects against Alzheimer's disease-like neuropathology in 3xTg-AD mice and MC65 cells.Can Co-Activation of Nrf2 and Neurotrophic Signaling Pathway Slow Alzheimer's Disease?Circadian Disruption Reveals a Correlation of an Oxidative GSH/GSSG Redox Shift with Learning and Impaired Memory in an Alzheimer's Disease Mouse Model.Modulation of Mitochondrial Membrane Potential and ROS Generation by Nicotinamide in a Manner Independent of SIRT1 and MitophagyAxonal Degeneration during Aging and Its Functional Role in Neurodegenerative DisordersNicotinamide pre-treatment ameliorates NAD(H) hyperoxidation and improves neuronal function after severe hypoxia.Salidroside protects PC12 cells from Aβ1‑40‑induced cytotoxicity by regulating the nicotinamide phosphoribosyltransferase signaling pathway.Dual-energy precursor and nuclear erythroid-related factor 2 activator treatment additively improve redox glutathione levels and neuron survival in aging and Alzheimer mouse neurons upstream of reactive oxygen species.External cys/cySS redox state modification controls the intracellular redox state and neurodegeneration via Akt in aging and Alzheimer's disease mouse model neurons.Emodin extends lifespan of Caenorhabditis elegans through insulin/IGF-1 signaling pathway depending on DAF-16 and SIR-2.1.Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's disease.Reduced cognitive function, increased blood-brain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr -/-and C57BL/6 mice fed a western diet.A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor.TPPU protects tau from H2O2-induced hyperphosphorylation in HEK293/tau cells by regulating PI3K/AKT/GSK-3β pathway.Fibrillar Amyloid-β Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3×Tg-AD Transgenic Mouse.Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice.Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States.
P2860
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P2860
A reversible early oxidized redox state that precedes macromolecular ROS damage in aging nontransgenic and 3xTg-AD mouse neurons
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
A reversible early oxidized re ...... enic and 3xTg-AD mouse neurons
@ast
A reversible early oxidized re ...... enic and 3xTg-AD mouse neurons
@en
type
label
A reversible early oxidized re ...... enic and 3xTg-AD mouse neurons
@ast
A reversible early oxidized re ...... enic and 3xTg-AD mouse neurons
@en
prefLabel
A reversible early oxidized re ...... enic and 3xTg-AD mouse neurons
@ast
A reversible early oxidized re ...... enic and 3xTg-AD mouse neurons
@en
P2093
P2860
P1476
A reversible early oxidized re ...... enic and 3xTg-AD mouse neurons
@en
P2093
Aaron J Barnett
Debolina Ghosh
Gregory J Brewer
Kelsey R LeVault
P2860
P304
P356
10.1523/JNEUROSCI.6192-11.2012
P407
P577
2012-04-01T00:00:00Z