DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2.
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Cellular and molecular biology of small cell lung cancer: an overviewOrigins, genetic landscape, and emerging therapies of small cell lung cancerA DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivoPrognostic significance of CpG island methylator phenotype in surgically resected small cell lung carcinoma.Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?Patient-derived xenografts faithfully replicated clinical outcome in a phase II co-clinical trial of arsenic trioxide in relapsed small cell lung cancerAberrant epigenetic regulation in clear cell sarcoma of the kidney featuring distinct DNA hypermethylation and EZH2 overexpression.A combinatorial strategy for treating KRAS-mutant lung cancerThe importance of detailed epigenomic profiling of different cell types within organs.Genome-wide methylation profiling of ovarian cancer patient-derived xenografts treated with the demethylating agent decitabine identifies novel epigenetically regulated genes and pathways.Epigenetic Regulation of the Epithelial to Mesenchymal Transition in Lung Cancer.The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type.Hypermethylation of adjacent CpG sites is negatively correlated with the expression of lineage oncogene ASCL1 in pulmonary neuroendocrine tumors.Unravelling the biology of SCLC: implications for therapy.Histone H3.3K27M Represses p16 to Accelerate Gliomagenesis in a Murine Model of DIPG.MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition.Family matters: How MYC family oncogenes impact small cell lung cancer.Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma-like and Non-Small Cell Carcinoma-like Subsets.A regulatory circuit composed of DNA methyltransferases and receptor tyrosine kinases controls lung cancer cell aggressiveness.Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.Comparison and combination of blood DNA methylation at smoking-associated genes and at lung cancer-related genes in prediction of lung cancer mortality.PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer.Altering the Course of Small Cell Lung Cancer: Targeting Cancer Stem Cells via LSD1 Inhibition.Relationship of tumor PD-L1 (CD274) expression with lower mortality in lung high-grade neuroendocrine tumor.ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs.Antitumor activity of LSD1 inhibitors in lung cancer.Reciprocal expression of INSM1 and YAP1 defines subgroups in small cell lung cancer.Relevance of genetic alterations in squamous and small cell lung cancer.Alternative Splicing of EZH2 pre-mRNA by SF3B3 Contributes to the Tumorigenic Potential of Renal Cancer.Small-cell lung cancer: what we know, what we need to know and the path forward.ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer.An approach to suppress the evolution of resistance in BRAFV600E-mutant cancer.Biology and evolution of poorly differentiated neuroendocrine tumors.Bridging the divide: preclinical research discrepancies between triple-negative breast cancer cell lines and patient tumors.Targeting DNA damage repair in small cell lung cancer and the biomarker landscape.Sodium Valproate Inhibits Small Cell Lung Cancer Tumor Growth on the Chicken Embryo Chorioallantoic Membrane and Reduces the p53 and EZH2 Expression.Transcriptional deregulation underlying the pathogenesis of small cell lung cancer.EZH2 Inhibition Ameliorates Transverse Aortic Constriction-Induced Pulmonary Arterial Hypertension in Mice.Redox-responsive self-assembly PEG nanoparticle enhanced triptolide for efficient antitumor treatment
P2860
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P2860
DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
DNA methylation in small cell ...... with high expression of EZH2.
@ast
DNA methylation in small cell ...... with high expression of EZH2.
@en
type
label
DNA methylation in small cell ...... with high expression of EZH2.
@ast
DNA methylation in small cell ...... with high expression of EZH2.
@en
prefLabel
DNA methylation in small cell ...... with high expression of EZH2.
@ast
DNA methylation in small cell ...... with high expression of EZH2.
@en
P2093
P2860
P356
P1433
P1476
DNA methylation in small cell ...... with high expression of EZH2.
@en
P2093
A L Moreira
E E Gardner
E de Stanchina
P2860
P2888
P304
P356
10.1038/ONC.2015.38
P407
P577
2015-03-09T00:00:00Z