Interleukin-25 induces type 2 cytokine production in a steroid-resistant interleukin-17RB+ myeloid population that exacerbates asthmatic pathology - Wikidata - wikimedia - TriplyDB

Interleukin-25 induces type 2 cytokine production in a steroid-resistant interleukin-17RB+ myeloid population that exacerbates asthmatic pathology

Interleukin-25 induces type 2 cytokine production in a steroid-resistant interleukin-17RB+ myeloid population that exacerbates asthmatic pathology

http://www.wikidata.org/entity/Q36044280

about

The roles and functional mechanisms of interleukin-17 family cytokines in mucosal immunity Interleukin (IL)-25: Pleiotropic roles in asthma Concerted activity of IgG1 antibodies and IL-4/IL-25-dependent effector cells trap helminth larvae in the tissues following vaccination with defined secreted antigens, providing sterile immunity to challenge infection Effect of IL-17 receptor A blockade with brodalumab in inflammatory diseases GM-CSF produced by the airway epithelium is required for sensitization to cockroach allergen Cytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33) and asthma.Subsets of airway myeloid-derived regulatory cells distinguish mild asthma from chronic obstructive pulmonary disease.Rhinovirus infection induces interleukin-13 production from CD11b-positive, M2-polarized exudative macrophages Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33.Increased expression of upstream TH2-cytokines in a mouse model of viral-induced asthma exacerbation.High IFN-γ and low SLPI mark severe asthma in mice and humans.Cutting Edge: IL-25 Targets Dendritic Cells To Attract IL-9-Producing T Cells in Acute Allergic Lung Inflammation.The Haemophilus influenzae Sap transporter mediates bacterium-epithelial cell homeostasis.Eotaxin-Rich Proangiogenic Hematopoietic Progenitor Cells and CCR3+ Endothelium in the Atopic Asthmatic Response.Nascent endothelium initiates Th2 polarization of asthma.Innate lymphoid cells in asthma: Will they take your breath away?From bedside to bench to clinic trials: identifying new treatments for severe asthma IL-17E (IL-25) and IL-17RB promote respiratory syncytial virus-induced pulmonary disease Characterization of CD4+ T cell subsets in allergy.Vascular endothelial growth factor as a key inducer of angiogenesis in the asthmatic airways.Th2 cytokine antagonists: potential treatments for severe asthma.Asthma: the importance of dysregulated barrier immunity.Rhinovirus-Induced Exacerbations of Asthma and COPD.The route to pathologies in chronic inflammatory diseases characterized by T helper type 2 immune cells.The need to differentiate between adults and children when treating severe asthma.IL-4 Induces IL17Rb Gene Transcription in Monocytic Cells with Coordinate Autocrine IL-25 Signaling.The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate matter under 10 μm.IL-17RB+ granulocytes are associated with airflow obstruction in asthma.Multi-allergen challenge stimulates steriod-resistant airway inflammation via NF-κB-mediated IL-8 expression.Allergic airway inflammation: key players beyond the Th2 cell pathway.IL-25 as a potential therapeutic target in allergic asthma.One mechanism of glucocorticoid action in asthma may involve the inhibition of IL-25 expression.Sputum cytokine mapping reveals an 'IL-5, IL-17A, IL-25-high' pattern associated with poorly controlled asthma.Dual role of interleukin-10 in the regulation of respiratory syncitial virus (RSV)-induced lung inflammation.Suppression of Inflammatory Arthritis by Human Gut-Derived Prevotella histicola in Humanized Mice.Thymic stromal lymphopoietin induces corticosteroid resistance in natural helper cells during airway inflammation.Allergy immunotherapy restores airway epithelial barrier dysfunction through suppressing IL-25 -induced endoplasmic reticulum stress in asthma.Pathogenesis of Recalcitrant Chronic Rhinosinusitis: The Emerging Role of Innate Immune Cells.Concerted IL-25R and IL-4Rα signaling drive innate type 2 effector immunity for optimal helminth expulsion

P2860

Q26750673-1D723682-B245-4D41-A4FB-FF72178F00A9 Q26772165-5A4E98FD-DA27-4DB5-A186-997DFC05C92E Q27321230-7B0AD20D-6954-4D2D-BAAC-D8A66F1FA650 Q28076496-5F6C3898-5D87-4F91-A728-F8F64D787F22 Q33559067-7256C819-A4E7-42FF-B9D0-BBFA5E9B70AE Q33776158-C1375FE3-C98E-4AE2-BEB1-2DB1CD35E4C9 Q35071370-368CB160-5E54-46A8-9D5B-0E470AF9CBE7 Q35207665-CF5A9166-853B-47C1-A616-FC8CF4A99064 Q35828725-7E63DA22-FAF7-4980-899D-8204DC21A067 Q35924449-DD621D5F-E553-4259-9D37-62820024EFB6 Q36040504-D1AABCA5-DB81-4454-A80B-68B29F941D49 Q36119440-4C570D82-72BC-48F1-BA79-DB37BE2E798E Q36506110-AFA344D0-C85D-462B-A5B5-262B5E388271 Q36601063-88784E09-F2E5-4792-8C49-B23B06739A38 Q36717794-8FE98536-6BC9-4AF2-B966-EE2A8985F172 Q36973089-3AC06F71-7EA9-4F45-8C02-E24E7D4C3182 Q36981794-4CB078D5-0121-410E-9F31-0CA7E38FFA8C Q37700171-75BF1309-06C5-4D7E-A90A-C9559CC99127 Q38034308-E7ADA67F-381B-48B7-84C8-8D0198C2F4B1 Q38053080-DA5092CC-9651-4B3E-9697-176CEF8DEBF6 Q38057796-36034385-07B9-4103-A030-19B5C93EEE61 Q38156031-07834268-CC5C-4D14-82CA-531D42DE9236 Q38166378-0DAB789F-CBEF-4A72-81CD-EF815DCAD148 Q38224933-FE26477E-13BF-4114-A5BB-8465E8F2AD7B Q38547303-648A7443-5D5F-4C15-A5A5-CC87F3A73502 Q38706963-95FB1D70-17B1-42A3-AF5E-C41537AEE082 Q38978747-BD78C940-0CA2-4890-A94A-CC5FA73A3256 Q39039562-521C7FE0-E6D2-49AD-B024-3BE7B4F937D1 Q39186003-A93579D5-76C5-4ED8-AA3C-A2F9785CD672 Q39402866-C5AF09F1-A556-4AFA-A7A6-97B39C6CA289 Q41649902-2904DB07-D819-4A4F-926D-B885D1C1473A Q42316682-63CB334C-FBDC-41FE-AE14-A03D59EB4E2B Q44487970-31A89E18-47CA-43B6-B46C-D3AA45E1100E Q45351747-B3A180E4-7797-42BC-939C-9089DB81D4D2 Q46528356-1461B7A1-7C86-4B51-8D75-3BCC64582173 Q53085315-4D3B584D-1784-4B61-973E-4AD0C8D4F83C Q54937942-EA99391F-FD0C-4D86-A056-7824F017EADC Q55242373-073607EA-0BE9-46BA-B7B2-E684454E26E6 Q58703285-D6CE3EF3-4F42-4169-9A9D-E8FF36EE1B24

P2860

Interleukin-25 induces type 2 cytokine production in a steroid-resistant interleukin-17RB+ myeloid population that exacerbates asthmatic pathology

http://www.wikidata.org/entity/Q36044280

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Interleukin-25 induces type 2 ...... xacerbates asthmatic pathology

@ast

Interleukin-25 induces type 2 ...... xacerbates asthmatic pathology

@en

type

label

Interleukin-25 induces type 2 ...... xacerbates asthmatic pathology

@ast

Interleukin-25 induces type 2 ...... xacerbates asthmatic pathology

@en

prefLabel

Interleukin-25 induces type 2 ...... xacerbates asthmatic pathology

@ast

Interleukin-25 induces type 2 ...... xacerbates asthmatic pathology

@en

P1433

Q36044280-EE37161D-696A-4CE1-A845-6215301ADA6B

P1476

Q36044280-1590A4C9-8999-48E5-BC44-501EEB431EAD

P2093

Q36044280-7E48208F-225A-44AF-85B2-F41DA155B62F

Q36044280-9A5705F9-35C3-4946-8833-A99424404140

Q36044280-CAE7DB26-E600-416D-9F1A-DF063F78C396

Q36044280-D7728EAD-B15F-47FA-8408-642D3D4E4D49

Q36044280-F4C1FF90-CC44-4EFA-B445-DCB52526866C

P2860

Q36044280-11FDF925-114E-49DB-8E48-C2EE3FF85EC1

Q36044280-186EA498-E3E2-4736-A4F5-9F56FB078AB4

Q36044280-18999970-4E7F-4E07-837A-4220DAE516B8

Q36044280-1AD56416-2D33-4454-8F54-46F3B8C333AC

Q36044280-1FA783F0-1DE3-43A5-AAFF-1DFAB5EA85F4

Q36044280-20FD19D5-A6CD-4CD9-88B0-E66BFB31504C

Q36044280-21D0AD43-D7C9-482B-B7A7-9AC1DBBDDEAD

Q36044280-254D2ADC-DBA3-4D9F-BD1A-6BCC88CD2DBF

Q36044280-2CF7DCE6-D325-430F-9169-912FDE2361C0

Q36044280-345F1473-DC24-41AF-AA63-81210F4B4820

P2888

Q36044280-2BE0A4F6-0CF3-417D-A66C-78AE70BD9DDD

P304

Q36044280-EABCEC51-72D4-4846-8EFF-2FA9C37A8286

P31

Q36044280-9C1878C5-756C-4ADF-B2A5-8CF164DF70E8

P356

Q36044280-1DA51AEA-A61F-4894-B995-1E8E31EE0434

P407

Q36044280-A33EA144-421E-440B-B89D-DB4A53F4898E

P433

Q36044280-53427541-BD6D-4E0E-99F8-4709CB449F1B

P478

Q36044280-7C72E57F-1A10-4CDC-ADF3-2500DCAE6F45

P577

Q36044280-0A9A5649-71C6-445D-9DBA-B1927F7F72A1

P5875

Q36044280-C37AB127-3B17-489E-8130-E378536D6B91

P698

Q36044280-CF21B324-5646-4757-A1B5-40CAEF761576

P921

Q36044280-CB36577A-AC28-485C-BB1A-93C364D66E7B

Q36044280-bef84bb2-c50e-4d0d-a687-6932d0bf0174

P932

Q36044280-8C6FAF4A-AB50-425B-8D86-AC9D7C615383

P356

P1433

Nature Medicine

P1476

Interleukin-25 induces type 2 ...... xacerbates asthmatic pathology

@en

P2093

Alan P Baptist

http://www.w3.org/2001/XMLSchema#string

Alison L Budelsky

http://www.w3.org/2001/XMLSchema#string

Bryan C Petersen

http://www.w3.org/2001/XMLSchema#string

Matthew A Schaller

http://www.w3.org/2001/XMLSchema#string

Nicholas W Lukacs

http://www.w3.org/2001/XMLSchema#string

P2860

IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

IL25 elicits a multipotent progenitor cell population that promotes T(H)2 cytokine responses

IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells

Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion

Myeloid-derived suppressor cells as regulators of the immune system

IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo

IL-25 enhances allergic airway inflammation by amplifying a TH2 cell-dependent pathway in mice

Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities

Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells

P2888

P304

751-758

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NM.2735

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

18

http://www.w3.org/2001/XMLSchema#string

P577

2012-05-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

224867044

http://www.w3.org/2001/XMLSchema#string

P698

22543263

http://www.w3.org/2001/XMLSchema#string

P921

P932

3378776

http://www.w3.org/2001/XMLSchema#string