Interleukin-25 induces type 2 cytokine production in a steroid-resistant interleukin-17RB+ myeloid population that exacerbates asthmatic pathology
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The roles and functional mechanisms of interleukin-17 family cytokines in mucosal immunityInterleukin (IL)-25: Pleiotropic roles in asthmaConcerted activity of IgG1 antibodies and IL-4/IL-25-dependent effector cells trap helminth larvae in the tissues following vaccination with defined secreted antigens, providing sterile immunity to challenge infectionEffect of IL-17 receptor A blockade with brodalumab in inflammatory diseasesGM-CSF produced by the airway epithelium is required for sensitization to cockroach allergenCytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33) and asthma.Subsets of airway myeloid-derived regulatory cells distinguish mild asthma from chronic obstructive pulmonary disease.Rhinovirus infection induces interleukin-13 production from CD11b-positive, M2-polarized exudative macrophagesPersistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33.Increased expression of upstream TH2-cytokines in a mouse model of viral-induced asthma exacerbation.High IFN-γ and low SLPI mark severe asthma in mice and humans.Cutting Edge: IL-25 Targets Dendritic Cells To Attract IL-9-Producing T Cells in Acute Allergic Lung Inflammation.The Haemophilus influenzae Sap transporter mediates bacterium-epithelial cell homeostasis.Eotaxin-Rich Proangiogenic Hematopoietic Progenitor Cells and CCR3+ Endothelium in the Atopic Asthmatic Response.Nascent endothelium initiates Th2 polarization of asthma.Innate lymphoid cells in asthma: Will they take your breath away?From bedside to bench to clinic trials: identifying new treatments for severe asthmaIL-17E (IL-25) and IL-17RB promote respiratory syncytial virus-induced pulmonary diseaseCharacterization of CD4+ T cell subsets in allergy.Vascular endothelial growth factor as a key inducer of angiogenesis in the asthmatic airways.Th2 cytokine antagonists: potential treatments for severe asthma.Asthma: the importance of dysregulated barrier immunity.Rhinovirus-Induced Exacerbations of Asthma and COPD.The route to pathologies in chronic inflammatory diseases characterized by T helper type 2 immune cells.The need to differentiate between adults and children when treating severe asthma.IL-4 Induces IL17Rb Gene Transcription in Monocytic Cells with Coordinate Autocrine IL-25 Signaling.The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate matter under 10 μm.IL-17RB+ granulocytes are associated with airflow obstruction in asthma.Multi-allergen challenge stimulates steriod-resistant airway inflammation via NF-κB-mediated IL-8 expression.Allergic airway inflammation: key players beyond the Th2 cell pathway.IL-25 as a potential therapeutic target in allergic asthma.One mechanism of glucocorticoid action in asthma may involve the inhibition of IL-25 expression.Sputum cytokine mapping reveals an 'IL-5, IL-17A, IL-25-high' pattern associated with poorly controlled asthma.Dual role of interleukin-10 in the regulation of respiratory syncitial virus (RSV)-induced lung inflammation.Suppression of Inflammatory Arthritis by Human Gut-Derived Prevotella histicola in Humanized Mice.Thymic stromal lymphopoietin induces corticosteroid resistance in natural helper cells during airway inflammation.Allergy immunotherapy restores airway epithelial barrier dysfunction through suppressing IL-25 -induced endoplasmic reticulum stress in asthma.Pathogenesis of Recalcitrant Chronic Rhinosinusitis: The Emerging Role of Innate Immune Cells.Concerted IL-25R and IL-4Rα signaling drive innate type 2 effector immunity for optimal helminth expulsion
P2860
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P2860
Interleukin-25 induces type 2 cytokine production in a steroid-resistant interleukin-17RB+ myeloid population that exacerbates asthmatic pathology
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Interleukin-25 induces type 2 ...... xacerbates asthmatic pathology
@ast
Interleukin-25 induces type 2 ...... xacerbates asthmatic pathology
@en
type
label
Interleukin-25 induces type 2 ...... xacerbates asthmatic pathology
@ast
Interleukin-25 induces type 2 ...... xacerbates asthmatic pathology
@en
prefLabel
Interleukin-25 induces type 2 ...... xacerbates asthmatic pathology
@ast
Interleukin-25 induces type 2 ...... xacerbates asthmatic pathology
@en
P2093
P2860
P356
P1433
P1476
Interleukin-25 induces type 2 ...... xacerbates asthmatic pathology
@en
P2093
Alan P Baptist
Alison L Budelsky
Bryan C Petersen
Matthew A Schaller
Nicholas W Lukacs
P2860
P2888
P304
P356
10.1038/NM.2735
P407
P577
2012-05-01T00:00:00Z