Systemic administration of the iron chelator deferiprone protects against light-induced photoreceptor degeneration in the mouse retina
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Retinal iron homeostasis in health and diseaseSarpogrelate, a 5-HT2A Receptor Antagonist, Protects the Retina From Light-Induced RetinopathyDrug-Based Lead Discovery: The Novel Ablative Antiretroviral Profile of Deferiprone in HIV-1-Infected Cells and in HIV-Infected Treatment-Naive Subjects of a Double-Blind, Placebo-Controlled, Randomized Exploratory TrialRetinal Neuroprotective Effects of Flibanserin, an FDA-Approved Dual Serotonin Receptor Agonist-AntagonistPostneonatal Mortality and Liver Changes in Cloned Pigs Associated with Human Tumor Necrosis Factor Receptor I-Fc and Human Heme Oxygenase-1 Overexpression.The oral iron chelator deferiprone protects against systemic iron overload-induced retinal degeneration in hepcidin knockout mice.Topical nutraceutical Optixcare EH ameliorates experimental ocular oxidative stress in rats.Microarray analysis of murine retinal light damage reveals changes in iron regulatory, complement, and antioxidant genes in the neurosensory retina and isolated RPE.Yttrium oxide nanoparticles prevent photoreceptor death in a light-damage model of retinal degeneration.Systemic administration of the antioxidant/iron chelator α-lipoic acid protects against light-induced photoreceptor degeneration in the mouse retina.Degeneration modulates retinal response to transient exogenous oxidative injury.Iron-induced Local Complement Component 3 (C3) Up-regulation via Non-canonical Transforming Growth Factor (TGF)-β Signaling in the Retinal Pigment Epithelium.Green tea extract attenuates MNU-induced photoreceptor cell apoptosis via suppression of heme oxygenase-1.CD1 Mouse Retina Is Shielded From Iron Overload Caused by a High Iron DietRetinal Pre-Conditioning by CD59a Knockout Protects against Light-Induced Photoreceptor Degeneration.The Oral Iron Chelator Deferiprone Protects Against Retinal Degeneration Induced through Diverse Mechanisms.Pretreatment with pyridoxamine mitigates isolevuglandin-associated retinal effects in mice exposed to bright light.Role of antioxidant enzymes and small molecular weight antioxidants in the pathogenesis of age-related macular degeneration (AMD)Fundus Camera-Delivered Light-Induced Retinal Degeneration in Mice With the RPE65 Leu450Met Variant is Associated With Oxidative Stress and ApoptosisOxidative stress and its downstream signaling in aging eyes."Pumping iron"-how macrophages handle iron at the systemic, microenvironmental, and cellular levelsMetal chelator combined with permeability enhancer ameliorates oxidative stress-associated neurodegeneration in rat eyes with elevated intraocular pressure.Role of iron in ischemia-induced neurodegeneration: mechanisms and insights.Retinal abnormalities in β-thalassemia major.Retinal structure and function preservation by polysaccharides of wolfberry in a mouse model of retinal degeneration.Berberine protects against light-induced photoreceptor degeneration in the mouse retinaComplement Components Showed a Time-Dependent Local Expression Pattern in Constant and Acute White Light-Induced Photoreceptor DamageAMD-like retinopathy associated with intravenous iron.Complement C5a receptor knockout has diminished light-induced microglia/macrophage retinal migration.The Oral Iron Chelator Deferiprone Protects Against Retinal Degeneration Induced through Diverse MechanismsA high serum iron level causes mouse retinal iron accumulation despite an intact blood-retinal barrierRenal iron accumulation occurs in lupus nephritis and iron chelation delays the onset of albuminuria.Cyanidin-3-glucoside and its phenolic acid metabolites attenuate visible light-induced retinal degeneration in vivo via activation of Nrf2/HO-1 pathway and NF-κB suppression.Retinal Basal Laminar Deposits in Complement fH/fP Mouse Model of Dense Deposit Disease.Pattern dystrophies in patients treated with deferoxamine: report of two cases and review of the literature
P2860
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P2860
Systemic administration of the iron chelator deferiprone protects against light-induced photoreceptor degeneration in the mouse retina
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Systemic administration of the ...... generation in the mouse retina
@ast
Systemic administration of the ...... generation in the mouse retina
@en
type
label
Systemic administration of the ...... generation in the mouse retina
@ast
Systemic administration of the ...... generation in the mouse retina
@en
prefLabel
Systemic administration of the ...... generation in the mouse retina
@ast
Systemic administration of the ...... generation in the mouse retina
@en
P2093
P2860
P1476
Systemic administration of the ...... generation in the mouse retina
@en
P2093
Joshua L Dunaief
Majda Hadziahmetovic
Yong Zhong
P2860
P356
10.1016/J.FREERADBIOMED.2012.04.020
P577
2012-05-01T00:00:00Z