Triazolothienopyrimidine inhibitors of urea transporter UT-B reduce urine concentration. - Wikidata - wikimedia - TriplyDB

Triazolothienopyrimidine inhibitors of urea transporter UT-B reduce urine concentration.

Triazolothienopyrimidine inhibitors of urea transporter UT-B reduce urine concentration.

http://www.wikidata.org/entity/Q36050904

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Pathophysiology, Evaluation, and Management of Edema in Childhood Nephrotic Syndrome Molecular mechanisms of urea transport in health and disease Structure of urea transporters Imaging Renal Urea Handling in Rats at Millimeter Resolution using Hyperpolarized Magnetic Resonance Relaxometry.Perspectives on edema in childhood nephrotic syndrome Emerging Targets of Diuretic Therapy.Detection of transgene expression using hyperpolarized 13C urea and diffusion-weighted magnetic resonance spectroscopy.Developing hypothetical inhibition mechanism of novel urea transporter B inhibitor.Diuresis and reduced urinary osmolality in rats produced by small-molecule UT-A-selective urea transport inhibitors.Nanomolar potency and metabolically stable inhibitors of kidney urea transporter UT-B.1,1-Difluoroethyl-substituted triazolothienopyrimidines as inhibitors of a human urea transport protein (UT-B): new analogs and binding model Thienoquinolins exert diuresis by strongly inhibiting UT-A urea transporters.A small molecule screen identifies selective inhibitors of urea transporter UT-A.Small-molecule inhibitors of urea transporters.Urea transporter inhibitors: en route to new diuretics.Structure-activity analysis of thiourea analogs as inhibitors of UT-A and UT-B urea transporters.Discovery, synthesis and structure-activity analysis of symmetrical 2,7-disubstituted fluorenones as urea transporter inhibitors.Salt-sparing diuretic action of a water-soluble urea analog inhibitor of urea transporters UT-A and UT-B in rats Urea transporter proteins as targets for small-molecule diuretics.Small-molecule CFTR activators increase tear secretion and prevent experimental dry eye disease Urea channel inhibitors: a new functional class of aquaretics Novel diuretic targets Development and validation of an LC-MS/MS method for the determination of a novel thienoquinolin urea transporter inhibitor PU-48 in rat plasma and its application to a pharmacokinetic study.Nanomolar-Potency 1,2,4-Triazoloquinoxaline Inhibitors of the Kidney Urea Transporter UT-A1.Pharmacokinetics, Tissue Distribution and Excretion of a Novel Diuretic (PU-48) in Rats

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P2860

Triazolothienopyrimidine inhibitors of urea transporter UT-B reduce urine concentration.

http://www.wikidata.org/entity/Q36050904

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Triazolothienopyrimidine inhibitors of urea transporter UT-B reduce urine concentration.

@ast

Triazolothienopyrimidine inhibitors of urea transporter UT-B reduce urine concentration.

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type

label

Triazolothienopyrimidine inhibitors of urea transporter UT-B reduce urine concentration.

@ast

Triazolothienopyrimidine inhibitors of urea transporter UT-B reduce urine concentration.

@en

prefLabel

Triazolothienopyrimidine inhibitors of urea transporter UT-B reduce urine concentration.

@ast

Triazolothienopyrimidine inhibitors of urea transporter UT-B reduce urine concentration.

@en

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P1433

Journal of the American Society of Nephrology

P1476

Triazolothienopyrimidine inhibitors of urea transporter UT-B reduce urine concentration.

@en

P2093

A S Verkman

http://www.w3.org/2001/XMLSchema#string

Baoxue Yang

http://www.w3.org/2001/XMLSchema#string

Chenjuan Yao

http://www.w3.org/2001/XMLSchema#string

Jicheng Zhang

http://www.w3.org/2001/XMLSchema#string

Marc O Anderson

http://www.w3.org/2001/XMLSchema#string

Puay-Wah Phuan

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P2860

Crystal structure of a bacterial homologue of the kidney urea transporter

A knowledge-based approach in designing combinatorial or medicinal chemistry libraries for drug discovery. 1. A qualitative and quantitative characterization of known drug databases

The SLC14 gene family of urea transporters

Analysis of double knockout mice lacking aquaporin-1 and urea transporter UT-B. Evidence for UT-B-facilitated water transport in erythrocytes

Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B

Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels

Urinary concentrating defect in mice with selective deletion of phloretin-sensitive urea transporters in the renal collecting duct

Impaired urea accumulation in the inner medulla of mice lacking the urea transporter UT-A2.

Urinary concentrating ability in patients with Jk(a-b-) blood type who lack carrier-mediated urea transport.

Characterization of the gene encoding the human Kidd blood group/urea transporter protein. Evidence for splice site mutations in Jknull individuals.

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1210-1220

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scholarly article

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10.1681/ASN.2011070751

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7

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23

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2012-04-05T00:00:00Z

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22491419

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3380644

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