Specific inactivation of two immunomodulatory SIGLEC genes during human evolution.
about
Rapid evolution of binding specificities and expression patterns of inhibitory CD33-related Siglecs in primatesWhy are there no persisting hybrids of humans with Denisovans, Neanderthals, or anyone else?Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus.Human-specific epigenetic variation in the immunological Leukotriene B4 Receptor (LTB4R/BLT1) implicated in common inflammatory diseasesEvolution of genetic and genomic features unique to the human lineage.The interplay between Siglecs and sialylated pathogensSiglec-mediated regulation of immune cell function in disease.Widespread divergence of the CEACAM/PSG genes in vertebrates and humans suggests sensitivity to selectionAllergies, Helicobacter pylori and the continental enigmasGlycan evolution in response to collaboration, conflict, and constraintEvolutionary inactivation of a sialidase in group B StreptococcusDirect radiocarbon dating and genetic analyses on the purported Neanderthal mandible from the Monti Lessini (Italy)Evolution and diversity of copy number variation in the great ape lineageSiglec-7 restores β-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes.Molecular biology of drug resistance in Mycobacterium tuberculosisThe nutritional role of free sialic acid, a human milk monosaccharide, and its application as a functional food ingredient.Antibiotic resistance mechanisms in M. tuberculosis: an update.Up-regulation of the human-specific CHRFAM7A gene in inflammatory bowel disease.Ancient oncogenesis, infection and human evolution.A genomics approach reveals insights into the importance of gene losses for mammalian adaptations.Examination of Signatures of Recent Positive Selection on Genes Involved in Human Sialic Acid Biology.The Role of aDNA in Understanding the Coevolutionary Patterns of Human Sexually Transmitted Infections
P2860
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P2860
Specific inactivation of two immunomodulatory SIGLEC genes during human evolution.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Specific inactivation of two immunomodulatory SIGLEC genes during human evolution.
@ast
Specific inactivation of two immunomodulatory SIGLEC genes during human evolution.
@en
type
label
Specific inactivation of two immunomodulatory SIGLEC genes during human evolution.
@ast
Specific inactivation of two immunomodulatory SIGLEC genes during human evolution.
@en
prefLabel
Specific inactivation of two immunomodulatory SIGLEC genes during human evolution.
@ast
Specific inactivation of two immunomodulatory SIGLEC genes during human evolution.
@en
P2093
P2860
P50
P356
P1476
Specific inactivation of two immunomodulatory SIGLEC genes during human evolution.
@en
P2093
Ajit Varki
Andrea Verhagen
Carlotta Balsamo
Chris Reid
Giorgio Corti
Ismael Secundino
Kalyan Banda
Laura Longo
Nivedita Mitra
P2860
P304
P356
10.1073/PNAS.1119459109
P407
P50
P577
2012-06-04T00:00:00Z