Thalidomide induces gamma-globin gene expression through increased reactive oxygen species-mediated p38 MAPK signaling and histone H4 acetylation in adult erythropoiesis.
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cJun modulates Ggamma-globin gene expression via an upstream cAMP response elementThe Role of Histone Acetyltransferases in Normal and Malignant HematopoiesisIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesMolecular mechanisms underlying synergistic adhesion of sickle red blood cells by hypoxia and low nitric oxide bioavailability.Optimal response to thalidomide in a patient with thalassaemia major resistant to conventional therapyTL1A both promotes and protects from renal inflammation and injury.Regulation of γ-globin gene expression involves signaling through the p38 MAPK/CREB1 pathway.Histone deacetylase inhibitors and hemoglobin F induction in beta-thalassemiaThalidomide influences growth and vasculogenic mimicry channel formation in melanoma.Cell signaling pathways involved in drug-mediated fetal hemoglobin induction: Strategies to treat sickle cell diseaseThe Molecular and Pharmacological Mechanisms of HIV-Related Neuropathic Pain.Epigenetic regulation of Kcna3-encoding Kv1.3 potassium channel by cereblon contributes to regulation of CD4+ T-cell activation.Short-chain fatty acid-mediated effects on erythropoiesis in primary definitive erythroid cells.A common signaling pathway is activated in erythroid cells expressing high levels of fetal hemoglobin: a potential role for cAMP-elevating agents in β-globin disorders.New nucleophilic mechanisms of ros-dependent epigenetic modifications: comparison of aging and cancer.Investigational drugs in sickle cell anemia.Evaluation of Signaling Pathways Involved in γ-Globin Gene Induction Using Fetal Hemoglobin Inducer Drugs.Evaluation of Novel Fetal Hemoglobin Inducer Drugs in Treatment of β-Hemoglobinopathy Disorders.Thalidomide Induces Haematologic Responses in Patients with β-Thalassaemia.Natural Remedies for the Treatment of Beta-Thalassemia and Sickle Cell Anemia-Current Status and Perspectives in Fetal Hemoglobin Reactivation.Modulation of cereblon levels by anti-myeloma agents.What are the most promising emerging therapies for sickle cell disease?Thalidomide is more efficient than sodium butyrate in enhancing GATA-1 and EKLF gene expression in erythroid progenitors derived from HSCs with β-globin gene mutation.The role of epigenetics in the induction of fetal hemoglobin: a combination therapy approach.Ferroportin and erythroid cells: an update.Molecular targeting of inosine-5'-monophosphate dehydrogenase by FF-10501 promotes erythropoiesis via ROS/MAPK pathway.Drosophila glob1 expresses dynamically and is required for development and oxidative stress response.Thalidomide has a significant effect in patients with thalassemia intermedia.Regulation of p38, PKC/Foxo3a/p73 signaling network by GTP during erythroid differentiation in chronic myelogenous leukemia.
P2860
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P2860
Thalidomide induces gamma-globin gene expression through increased reactive oxygen species-mediated p38 MAPK signaling and histone H4 acetylation in adult erythropoiesis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Thalidomide induces gamma-glob ...... ation in adult erythropoiesis.
@ast
Thalidomide induces gamma-glob ...... ation in adult erythropoiesis.
@en
type
label
Thalidomide induces gamma-glob ...... ation in adult erythropoiesis.
@ast
Thalidomide induces gamma-glob ...... ation in adult erythropoiesis.
@en
prefLabel
Thalidomide induces gamma-glob ...... ation in adult erythropoiesis.
@ast
Thalidomide induces gamma-glob ...... ation in adult erythropoiesis.
@en
P2093
P2860
P1433
P1476
Thalidomide induces gamma-glob ...... ation in adult erythropoiesis.
@en
P2093
Griffin P Rodgers
Jianqiong Zhu
Kyung Chin
Wulin Aerbajinai
Zhigang Gao
P2860
P304
P356
10.1182/BLOOD-2007-01-065201
P407
P577
2007-07-09T00:00:00Z