Anti beta2-microglobulin monoclonal antibodies induce apoptosis in myeloma cells by recruiting MHC class I to and excluding growth and survival cytokine receptors from lipid rafts.
about
Some basic aspects of HLA-G biologyβ2-Microglobulin-mediated signaling as a target for cancer therapyDecipher β2-microglobulin: gain- or loss-of-function (a mini-review)RANK-mediated signaling network and cancer metastasis.Killing tumor cells through their surface beta(2)-microglobulin or major histocompatibility complex class I molecules.Novel immunotherapiesA critical role of autocrine sonic hedgehog signaling in human CD138+ myeloma cell survival and drug resistance.Inhibition of β2-microglobulin/hemochromatosis enhances radiation sensitivity by induction of iron overload in prostate cancer cellsTargeting cell surface β2 -microglobulin by pentameric IgM antibodiesβ2-microglobulin induces epithelial to mesenchymal transition and confers cancer lethality and bone metastasis in human cancer cells.Therapeutic monoclonal antibodies for multiple myeloma: an update and future perspectives.p38 MAPK in myeloma cells regulates osteoclast and osteoblast activity and induces bone destruction.Upregulation of β2-microglobulin expression in progressive human oral squamous cell carcinomaThe Implication and Significance of Beta 2 Microglobulin: A Conservative Multifunctional Regulator.Human-like mouse models for testing the efficacy and safety of anti-beta2-microglobulin monoclonal antibodies to treat myelomaTargeting Human β-Microglobulin with Monoclonal Antibodies in Multiple Myeloma - A Potential in Treatment.Humoral immunotherapy of multiple myeloma: perspectives and perplexities.Novel strategies for immunotherapy in multiple myeloma: previous experience and future directions.Monoclonal antibody-based immunotherapy for multiple myeloma.Serum beta-2 microglobulin in malignant lymphomas: an old but powerful prognostic factor.Small molecule antibody targeting HLA class I inhibits myeloma cancer stem cells by repressing pluripotency-associated transcription factors.HLA-G inhibition of NK-cell cytolytic function is uncoupled from tumor cell lipid raft reorganization.Beta2-microglobulin as a potential factor for the expansion of mesenchymal stem cells.
P2860
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P2860
Anti beta2-microglobulin monoclonal antibodies induce apoptosis in myeloma cells by recruiting MHC class I to and excluding growth and survival cytokine receptors from lipid rafts.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Anti beta2-microglobulin monoc ...... ne receptors from lipid rafts.
@ast
Anti beta2-microglobulin monoc ...... ne receptors from lipid rafts.
@en
type
label
Anti beta2-microglobulin monoc ...... ne receptors from lipid rafts.
@ast
Anti beta2-microglobulin monoc ...... ne receptors from lipid rafts.
@en
prefLabel
Anti beta2-microglobulin monoc ...... ne receptors from lipid rafts.
@ast
Anti beta2-microglobulin monoc ...... ne receptors from lipid rafts.
@en
P2093
P2860
P1433
P1476
Anti beta2-microglobulin monoc ...... ne receptors from lipid rafts.
@en
P2093
Jianfei Qian
Larry W Kwak
Liang Zhang
Michael Wang
Xiang Zhang
P2860
P304
P356
10.1182/BLOOD-2007-06-094417
P407
P577
2007-07-20T00:00:00Z