A conformational transition in the adenylyl cyclase catalytic site yields different binding modes for ribosyl-modified and unmodified nucleotide inhibitors
about
Novel inhibitors of anthrax edema factor.Structural basis for the high-affinity inhibition of mammalian membranous adenylyl cyclase by 2',3'-o-(N-methylanthraniloyl)-inosine 5'-triphosphate.Structure-activity relationships for the interactions of 2'- and 3'-(O)-(N-methyl)anthraniloyl-substituted purine and pyrimidine nucleotides with mammalian adenylyl cyclases.Inhibition of the adenylyl cyclase toxin, edema factor, from Bacillus anthracis by a series of 18 mono- and bis-(M)ANT-substituted nucleoside 5'-triphosphates.Molecular analysis of the interaction of anthrax adenylyl cyclase toxin, edema factor, with 2'(3')-O-(N-(methyl)anthraniloyl)-substituted purine and pyrimidine nucleotides.In memoriam. Angel Ramírez Ortiz (1966-2008).
P2860
A conformational transition in the adenylyl cyclase catalytic site yields different binding modes for ribosyl-modified and unmodified nucleotide inhibitors
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
A conformational transition in ...... modified nucleotide inhibitors
@ast
A conformational transition in ...... modified nucleotide inhibitors
@en
type
label
A conformational transition in ...... modified nucleotide inhibitors
@ast
A conformational transition in ...... modified nucleotide inhibitors
@en
prefLabel
A conformational transition in ...... modified nucleotide inhibitors
@ast
A conformational transition in ...... modified nucleotide inhibitors
@en
P2093
P2860
P1476
A conformational transition in ...... modified nucleotide inhibitors
@en
P2093
Gerald H Lushington
Jay J-Q Wu
Jenna L Wang
Jian-Xin Guo
Qi-Yuan Zhang
Roland Seifert
P2860
P304
P356
10.1016/J.BMC.2007.02.014
P407
P577
2007-02-11T00:00:00Z