Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy. - Wikidata - wikimedia - TriplyDB

Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.

Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.

http://www.wikidata.org/entity/Q36068290

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Molecular functions of thyroid hormones and their clinical significance in liver-related diseases Lacritin rescues stressed epithelia via rapid forkhead box O3 (FOXO3)-associated autophagy that restores metabolism Thyroid hormone-mediated autophagy and mitochondrial turnover in NAFLD Autophagy: a new target for nonalcoholic fatty liver disease therapy Thyroid hormones and the metabolic syndrome Thyroid hormone induction of mitochondrial activity is coupled to mitophagy via ROS-AMPK-ULK1 signaling The autophagy-related gene 14 (Atg14) is regulated by forkhead box O transcription factors and circadian rhythms and plays a critical role in hepatic autophagy and lipid metabolism Elucidating mechanisms of toxicity using phenotypic data from primary human cell systems--a chemical biology approach for thrombosis-related side effects.Metabolomic analysis shows differential hepatic effects of T2 and T3 in rats after short-term feeding with high fat diet.Thyroid hormone regulation of metabolism Ginsenoside Rb2 Alleviates Hepatic Lipid Accumulation by Restoring Autophagy via Induction of Sirt1 and Activation of AMPK.AMP-activated protein kinase regulates lipid metabolism and the fibrotic phenotype of hepatic stellate cells through inhibition of autophagy β-Adrenergic agonist and antagonist regulation of autophagy in HepG2 cells, primary mouse hepatocytes, and mouse liver Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance.Regulation of fatty acid composition and lipid storage by thyroid hormone in mouse liver.T₃-induced liver AMP-activated protein kinase signaling: redox dependency and upregulation of downstream targets Chromosome 19 open reading frame 80 is upregulated by thyroid hormone and modulates autophagy and lipid metabolism.Thyroid hormone signaling in energy homeostasis and energy metabolism.Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cells Plasma proteome and metabolome characterization of an experimental human thyrotoxicosis model Transcriptional and Chromatin Regulation during Fasting - The Genomic Era Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo.Emerging roles of the corepressors NCoR1 and SMRT in homeostasis.Androgens promote prostate cancer cell growth through induction of autophagy.Functions of autophagy in normal and diseased liver.TP53INP2/DOR, a mediator of cell autophagy, promotes rDNA transcription via facilitating the assembly of the POLR1/RNA polymerase I preinitiation complex at rDNA promoters.FoxO1 deacetylation regulates thyroid hormone-induced transcription of key hepatic gluconeogenic genes.The REGγ proteasome regulates hepatic lipid metabolism through inhibition of autophagy.Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, stimulates hepatic autophagy and lipid clearance.Changes in macroautophagy, chaperone-mediated autophagy, and mitochondrial metabolism in murine skeletal and cardiac muscle during aging.Thyroid in 2012: Advances in thyroid development, hormone action and neoplasia.Lipid lowering effects of iodothyronines: In vivo and in vitro studies on rat liver.Role of autophagy in the pathophysiology of nonalcoholic fatty liver disease: a controversial issue.Thyroid hormone in the frontier of cell protection, survival and functional recovery.Breaking fat: The regulation and mechanisms of lipophagy.Emerging role of thyroid hormone metabolites.Thyroid hormone protects hepatocytes from HBx-induced carcinogenesis by enhancing mitochondrial turnover.Ruthenium complex Λ-WH0402 induces hepatocellular carcinoma LM6 (HCCLM6) cell death by triggering the Beclin-1-dependent autophagy pathway.Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice.

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P2860

Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.

http://www.wikidata.org/entity/Q36068290

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name

Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.

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Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.

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Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.

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Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.

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prefLabel

Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.

@ast

Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.

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Journal of Clinical Investigation

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Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.

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P2093

Boon-Huat Bay

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Christopher B Newgard

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Jin Zhou

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Martin L Privalsky

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Mitchell A Lazar

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Mobin M Siddique

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Paul M Yen

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Robert D Stevens

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Rohit Anthony Sinha

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Scott A Summers

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P2860

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

The nuclear receptor corepressor deacetylase activating domain is essential for repression by thyroid hormone receptor

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Physiological and molecular basis of thyroid hormone action

Is hypothyroidism a risk factor for non-alcoholic steatohepatitis?

A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptin

The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo

Transgenic targeting of a dominant negative corepressor to liver blocks basal repression by thyroid hormone receptor and increases cell proliferation

Autophagy regulates lipid metabolism

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7

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