Genetic variants associated with autoimmunity drive NFκB signaling and responses to inflammatory stimuli - Wikidata - wikimedia - TriplyDB

Genetic variants associated with autoimmunity drive NFκB signaling and responses to inflammatory stimuli

Genetic variants associated with autoimmunity drive NFκB signaling and responses to inflammatory stimuli

http://www.wikidata.org/entity/Q36071390

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Cellular and Molecular Mechanisms Underpinning Macrophage Activation during Remyelination Autoimmune diseases - connecting risk alleles with molecular traits of the immune system.Mucosal-Associated Invariant T Cells in Multiple Sclerosis: The Jury is Still Out NF-κB Pathways in the Pathogenesis of Multiple Sclerosis and the Therapeutic Implications The Multiple Sclerosis (MS) Genetic Risk Factors Indicate both Acquired and Innate Immune Cell Subsets Contribute to MS Pathogenesis and Identify Novel Therapeutic Opportunities.Genetic basis of autoimmunity.Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation GWAS analysis implicates NF-κB-mediated induction of inflammatory T cells in multiple sclerosis.CD40-Mediated NF-κB Activation in B Cells Is Increased in Multiple Sclerosis and Modulated by Therapeutics.Precision medicine, genomics and drug discovery.Experimental Models of Autoimmune Demyelinating Diseases in Nonhuman Primates.Small molecules to the rescue: Inhibition of cytokine signaling in immune-mediated diseases.Inflammation in the spotlight-clinical relevance of genetic variants affecting nuclear factor κB and tumor necrosis factor receptor 1.Evaluation of neurological changes in secondary progressive multiple sclerosis patients treated with immune modulator MIS416: results from a feasibility study.Balanced Bcl-3 expression in murine CD4+ T cells is required for generation of encephalitogenic Th17 cells.N-methyl-N-nitrosourea induces retinal degeneration in the rat via the inhibition of NF-κB activation.Genomic Effects of the Vitamin D Receptor: Potentially the Link between Vitamin D, Immune Cells, and Multiple Sclerosis.Nuclear Factor-kappaB in Autoimmunity: Man and Mouse.The Role of Astrocytes in Multiple Sclerosis.The Footprints of Poly-Autoimmunity: Evidence for Common Biological Factors Involved in Multiple Sclerosis and Hashimoto's Thyroiditis.Aberrant STAT phosphorylation signaling in peripheral blood mononuclear cells from multiple sclerosis patients.

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P2860

Genetic variants associated with autoimmunity drive NFκB signaling and responses to inflammatory stimuli

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Genetic variants associated wi ...... ponses to inflammatory stimuli

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Science Translational Medicine

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Genetic variants associated wi ...... ponses to inflammatory stimuli

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Jaime Grutzendler

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Kenneth Vera

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Laura Glick

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Mitja Mitrovic

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Nicole Cuerdon

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Phillip L De Jager

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Salvador D Fernandez

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Sasidhar R Murikinati

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An integrated encyclopedia of DNA elements in the human genome

An integrated map of genetic variation from 1,092 human genomes

TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

The accessible chromatin landscape of the human genome

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

PLINK: a tool set for whole-genome association and population-based linkage analyses

NF-κB, the first quarter-century: remarkable progress and outstanding questions

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