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Immunomodulation by mesenchymal stem cells: a potential therapeutic strategy for type 1 diabetesCentral role of defective interleukin-2 production in the triggering of islet autoimmune destructionHuman T regulatory cell therapy: take a billion or so and call me in the morningThe cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetesInhibition of autoimmune type 1 diabetes by gastrointestinal helminth infectionMemory T Cell MigrationThe clinical relevance of animal models in Sjögren's syndrome: the interferon signature from mouse to manDiabetes mellitus related bone metabolism and periodontal diseaseExperimental primates and non-human primate (NHP) models of human diseases in China: current status and progressThe Juvenile Diabetes Research Foundation Network for Pancreatic Organ Donors with Diabetes (nPOD) Program: goals, operational model and emerging findingsInsulitis in human type 1 diabetes: a comparison between patients and animal modelsBioluminescence imaging reveals dynamics of beta cell loss in the non-obese diabetic (NOD) mouse modelA bispecific protein capable of engaging CTLA-4 and MHCII protects non-obese diabetic mice from autoimmune diabetesInhibition of Autoimmune Diabetes in NOD Mice by miRNA TherapyMammalian lipoxygenases and their biological relevanceInterleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiationGenetics, pathogenesis and clinical interventions in type 1 diabetesThe role of the PD-1 pathway in autoimmunity and peripheral toleranceCan exposure to environmental chemicals increase the risk of diabetes type 1 development?How defects in central tolerance impinge on a deficiency in regulatory T cellsDeoxyhypusine synthase promotes differentiation and proliferation of T helper type 1 (Th1) cells in autoimmune diabetesThe role of TNF-α in mice with type 1- and 2- diabetesThe immunosuppressive role of adenosine A2A receptors in ischemia reperfusion injury and islet transplantation.Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes developmentAssociation of T-zone reticular networks and conduits with ectopic lymphoid tissues in mice and humansPD-1 deficiency reveals various tissue-specific autoimmunity by H-2b and dose-dependent requirement of H-2g7 for diabetes in NOD mice.Early over expression of messenger RNA for multiple genes, including insulin, in the Pancreatic Lymph Nodes of NOD mice is associated with Islet AutoimmunityGenome-wide end-sequenced BAC resources for the NOD/MrkTac() and NOD/ShiLtJ() mouse genomes.New data analysis and mining approaches identify unique proteome and transcriptome markers of susceptibility to autoimmune diabetes.Increased recruitment but impaired function of leukocytes during inflammation in mouse models of type 1 and type 2 diabetes.RasGAP-derived fragment N increases the resistance of beta cells towards apoptosis in NOD mice and delays the progression from mild to overt diabetes.Elevated CXCL12 expression in the bone marrow of NOD mice is associated with altered T cell and stem cell trafficking and diabetes development.IFN-gamma-dependent regulatory circuits in immune inflammation highlighted in diabetes.APC activation restores functional CD4(+)CD25(+) regulatory T cells in NOD mice that can prevent diabetes development.Detection of molecular paths associated with insulitis and type 1 diabetes in non-obese diabetic mousePrevention of diabetes in NOD mice by repeated exposures to a contact allergen inducing a sub-clinical dermatitis.Dendritic cells transduced to express interleukin 4 reduce diabetes onset in both normoglycemic and prediabetic nonobese diabetic miceIntrathymic injection of hematopoietic progenitor cells establishes functional T cell development in a mouse model of severe combined immunodeficiency.Suppression of ongoing T cell-mediated autoimmunity by peptide-MHC class II dimer vaccination.Molecular pathway alterations in CD4 T-cells of nonobese diabetic (NOD) mice in the preinsulitis phase of autoimmune diabetes.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
The NOD mouse: a model of immune dysregulation.
@ast
The NOD mouse: a model of immune dysregulation.
@en
type
label
The NOD mouse: a model of immune dysregulation.
@ast
The NOD mouse: a model of immune dysregulation.
@en
prefLabel
The NOD mouse: a model of immune dysregulation.
@ast
The NOD mouse: a model of immune dysregulation.
@en
P1476
The NOD mouse: a model of immune dysregulation.
@en
P2093
Jeffrey A Bluestone
Mark S Anderson
P304
P356
10.1146/ANNUREV.IMMUNOL.23.021704.115643
P577
2005-01-01T00:00:00Z