Studies of the regulation and function of the Gs alpha gene Gnas using gene targeting technology.
about
Targeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-IbTransgenerational Effects of Di-(2-Ethylhexyl) Phthalate (DEHP) on Stress Hormones and Behavior.Overlapping mouse subcongenic strains successfully separate two linked body fat QTL on distal MMU 2.Gsα deficiency in the dorsomedial hypothalamus underlies obesity associated with Gsα mutations.Increasing alternative promoter repertories is positively associated with differential expression and disease susceptibility.G protein coupled receptors in embryonic stem cells: a role for Gs-alpha signaling.DNA sequence polymorphisms within the bovine guanine nucleotide-binding protein Gs subunit alpha (Gsα)-encoding (GNAS) genomic imprinting domain are associated with performance traitsThe in vivo regulation of heart rate in the murine sinoatrial node by stimulatory and inhibitory heterotrimeric G proteins.Association of maternally inherited GNAS alleles with African-American male birth weightThe role of GNAS and other imprinted genes in the development of obesity.A review of osteocyte function and the emerging importance of sclerostinEvidence for alterations in stimulatory G proteins and oxytocin levels in children with autism.Effects of deficiency of the G protein Gsα on energy and glucose homeostasisLoss of methylation at GNAS exon A/B is associated with increased intrauterine growthDNA methylation of IGF2, GNASAS, INSIGF and LEP and being born small for gestational age.Paternally inherited gsα mutation impairs adipogenesis and potentiates a lean phenotype in vivo.Inherited human diseases of heterotopic bone formation.Severe obesity and insulin resistance due to deletion of the maternal Gsalpha allele is reversed by paternal deletion of the Gsalpha imprint control region.Heterozygous inactivation of Gnas in adipose-derived mesenchymal progenitor cells enhances osteoblast differentiation and promotes heterotopic ossificationThe extended granin family: structure, function, and biomedical implicationsUsing AAV vectors expressing the β2-adrenoceptor or associated Gα proteins to modulate skeletal muscle mass and muscle fibre size.Hypermethylation at loci sensitive to the prenatal environment is associated with increased incidence of myocardial infarction.Regulation of G-protein signaling via Gnas is required to regulate proximal tubular growth in the Xenopus pronephros.G(s)alpha deficiency in skeletal muscle leads to reduced muscle mass, fiber-type switching, and glucose intolerance without insulin resistance or deficiency.Central nervous system imprinting of the G protein G(s)alpha and its role in metabolic regulation.Physiological dysfunctions associated with mutations of the imprinted Gnas locus.SNPs in genes encoding G proteins in pharmacogenetics.Clinical proteomics in obstetrics and neonatology.Proteomic urinary biomarker approach in renal disease: from discovery to implementation.Methylation and transcripts expression at the imprinted GNAS locus in human embryonic and induced pluripotent stem cells and their derivatives.Impact of Consuming Extra-Virgin Olive Oil or Nuts within a Mediterranean Diet on DNA Methylation in Peripheral White Blood Cells within the PREDIMED-Navarra Randomized Controlled Trial: A Role for Dietary Lipids.Fetal Urinary Peptides to Predict Postnatal Outcome of Renal Disease in Fetuses with Posterior Urethral Valves (PUV)
P2860
Q28593878-7E7165F0-46ED-4310-BAC9-870614468B55Q30279027-E82CB022-F599-4BC5-AB65-8FF6C3870979Q30300906-EC376623-E4D2-4E29-8C57-DC0885D08CD7Q30352984-54BCC97E-735E-4D06-A7C0-2EAFBDB6EE12Q30979181-CEB0DAF3-955D-45ED-B500-5B3A04066EACQ33531731-CD2CF6E0-AD0E-477D-8E29-7C2FB5F48BA5Q33788424-E66E67D7-2768-41E9-842D-3860A1002182Q33816888-6A14F72B-A029-466F-97B0-AB7261AA522EQ34083377-F5A1B933-CE4C-45E8-BEFD-BE2D872C50D4Q34099397-F5F5B02C-B167-4B4B-989B-D7563148C29EQ34264395-2F9C751B-ADB6-4C80-9FD4-C9DE53FA1EF0Q34654354-A7621246-CD1D-4E91-81B7-89DD912F5E1BQ34883776-076180C6-2CB8-4D03-A6F2-FA6E89C18500Q35442006-101EE6FD-F437-4A84-8C17-594EE4DBA227Q35754822-77B27D2B-C452-4111-A912-551D32F52EABQ36122295-0BD42FC5-DB13-4DC3-9233-116543DAB5DBQ36552107-3948E1F7-0C29-4A95-95B2-D21533EF60A8Q36578863-65D9CE9D-4CF0-4406-841B-132E2FF67F23Q36645531-E7199709-8BEF-43BA-86A1-0BEEA5B491C4Q36666413-6A8325F4-6404-4304-8754-2577424F0230Q36682199-71104314-6D62-48D6-9A4F-476B0E0D8287Q36872686-458C1BAF-F0D8-4883-9D4B-44D6810A8C25Q37156419-96D40D2E-1EB7-4892-9194-0CB93CBFDB5DQ37162369-4354584E-7D75-4C4E-9D50-EA3172E84835Q37233680-702E1B9C-D729-4056-9EF1-1C3D7174F3AFQ37242244-834038DE-3DBE-4652-8178-FF87C43399CDQ37880876-16FD10CF-3BA9-4BB5-A526-77E139124086Q38176934-BCA2CA1E-9439-470D-8103-5754F9AE02B8Q38196316-C85D3A73-6312-4296-9EF6-8B1073A77F51Q38954631-4B9509AD-C5A7-49E7-A628-848B3A2546B4Q48320024-055AAB33-8042-4A02-A229-60E70CE3B452Q57711889-3DA6824D-ABFF-4EC1-A34E-7A6413EE216A
P2860
Studies of the regulation and function of the Gs alpha gene Gnas using gene targeting technology.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Studies of the regulation and ...... ing gene targeting technology.
@ast
Studies of the regulation and ...... ing gene targeting technology.
@en
type
label
Studies of the regulation and ...... ing gene targeting technology.
@ast
Studies of the regulation and ...... ing gene targeting technology.
@en
prefLabel
Studies of the regulation and ...... ing gene targeting technology.
@ast
Studies of the regulation and ...... ing gene targeting technology.
@en
P2093
P2860
P1476
Studies of the regulation and ...... ing gene targeting technology.
@en
P2093
Lee S Weinstein
Qing-Hong Zhang
P2860
P304
P356
10.1016/J.PHARMTHERA.2007.03.013
P577
2007-04-21T00:00:00Z