Signaling for NKT cell development: the SAP-FynT connection
about
The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functionsHomotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage developmentTranscription factor Bcl11b controls selection of invariant natural killer T-cells by regulating glycolipid presentation in double-positive thymocytesThe sequential activity of Gata3 and Thpok is required for the differentiation of CD1d-restricted CD4+ NKT cellsThe transcription factor c-Myb primes CD4+CD8+ immature thymocytes for selection into the iNKT lineage.Stepwise development of MAIT cells in mouse and humanWiskott-Aldrich syndrome protein is required for homeostasis and function of invariant NKT cells.The Ras/MAPK pathway is required for generation of iNKT cells.Invariant NKT cell development requires a full complement of functional CD3 zeta immunoreceptor tyrosine-based activation motifsNKT Cell Subsets Can Exert Opposing Effects in Autoimmunity, Tumor Surveillance and InflammationDecision checkpoints in the thymus.Recognition of lipid antigens by T cells.Pak2 Controls Acquisition of NKT Cell Fate by Regulating Expression of the Transcription Factors PLZF and Egr2.SAP is required for the development of innate phenotype in H2-M3--restricted Cd8(+) T cells.Characterization of the early stages of thymic NKT cell development.Thymic microenvironments for T cell differentiation and selection.The role of SLAM family receptors in immune cell signaling.Natural killer T cells in health and disease.TNF receptor associated factor 3 plays a key role in development and function of invariant natural killer T cells.The Tec kinases Itk and Rlk regulate conventional versus innate T-cell development.Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation.Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/TxkThe gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cellsRaising the NKT cell family.SLAM family receptors and the SLAM-associated protein (SAP) modulate T cell functions.Loss of microRNAs in thymus perturbs invariant NKT cell development and functionSAP-Dependent and -Independent Regulation of Innate T Cell Development Involving SLAMF Receptors.Regulatory T-cell as orchestra leader in immunosuppression process of multiple sclerosis.Control of early stages in invariant natural killer T-cell development.Different subsets of natural killer T cells may vary in their roles in health and disease.Invariant natural killer T cells in hematopoietic stem cell transplantation: killer choice for natural suppression.Inhibition of CD1 antigen presentation by human cytomegalovirus.Natural killer T cell strategies to combat Epstein-Barr virus infection.Normal development and activation but altered cytokine production of Fyn-deficient CD4+ T cells.Distinct roles in NKT cell maturation and function for the different transcription factors in the classical NF-κB pathway.Tissue-Resident Lymphocytes Across Innate and Adaptive Lineages
P2860
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P2860
Signaling for NKT cell development: the SAP-FynT connection
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Signaling for NKT cell development: the SAP-FynT connection
@ast
Signaling for NKT cell development: the SAP-FynT connection
@en
type
label
Signaling for NKT cell development: the SAP-FynT connection
@ast
Signaling for NKT cell development: the SAP-FynT connection
@en
prefLabel
Signaling for NKT cell development: the SAP-FynT connection
@ast
Signaling for NKT cell development: the SAP-FynT connection
@en
P2860
P921
P356
P1476
Signaling for NKT cell development: the SAP-FynT connection
@en
P2093
Albert Bendelac
Christine Borowski
P2860
P304
P356
10.1084/JEM.20050339
P407
P577
2005-03-01T00:00:00Z
2005-03-21T00:00:00Z