Detection of hypoxia by measurement of DNA damage in individual cells from spheroids and murine tumours exposed to bioreductive drugs. I. Tirapazamine.

Detection of hypoxia by measurement of DNA damage in individual cells from spheroids and murine tumours exposed to bioreductive drugs. I. Tirapazamine.

Item
http://www.wikidata.org/entity/Q36080580
Improved potency of the hypoxic cytotoxin tirapazamine by DNA-targeting.Tirapazamine-induced DNA damage measured using the comet assay correlates with cytotoxicity towards hypoxic tumour cells in vitro.Heterogeneity in DNA damage using the comet assay.Prospects for bioreductive drug development.Comparison between the comet assay and pimonidazole binding for measuring tumour hypoxia.Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death.Radiologic differences between bone marrow stromal and hematopoietic progenitor cell lines from Fanconi Anemia (Fancd2(-/-)) mice.Overexpression of the human manganese superoxide dismutase (MnSOD) transgene in subclones of murine hematopoietic progenitor cell line 32D cl 3 decreases irradiation-induced apoptosis but does not alter G2/M or G1/S phase cell cycle arrest.Evaluation of a novel in vitro assay for assessing drug penetration into avascular regions of tumours.Intratracheal injection of manganese superoxide dismutase (MnSOD) plasmid/liposomes protects normal lung but not orthotopic tumors from irradiation.
P2860

Detection of hypoxia by measurement of DNA damage in individual cells from spheroids and murine tumours exposed to bioreductive drugs. I. Tirapazamine.

Item
http://www.wikidata.org/entity/Q36080580
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Detection of hypoxia by measur ...... uctive drugs. I. Tirapazamine.
@ast
Detection of hypoxia by measur ...... uctive drugs. I. Tirapazamine.
@en
type
label
Detection of hypoxia by measur ...... uctive drugs. I. Tirapazamine.
@ast
Detection of hypoxia by measur ...... uctive drugs. I. Tirapazamine.
@en
prefLabel
Detection of hypoxia by measur ...... uctive drugs. I. Tirapazamine.
@ast
Detection of hypoxia by measur ...... uctive drugs. I. Tirapazamine.
@en
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P577
P5875
P6179
P698
P921
P932
P356
P1433
P1476
Detection of hypoxia by measur ...... uctive drugs. I. Tirapazamine.
@en
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P577
P5875
P6179
P698
P921
P932