Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy
about
A structural ensemble of a ribosome-nascent chain complex during cotranslational protein folding.Cotranslational structure acquisition of nascent polypeptides monitored by NMR spectroscopyFolding study of Venus reveals a strong ion dependence of its yellow fluorescence under mildly acidic conditions.Directionality in protein fold prediction.Structural analysis of a signal peptide inside the ribosome tunnel by DNP MAS NMRNMR analysis of the architecture and functional remodeling of a modular multidomain protein, RPA.Probing ribosome-nascent chain complexes produced in vivo by NMR spectroscopy.Dynamic fluorescence depolarization: a powerful tool to explore protein folding on the ribosomeProtein folding at the exit tunnel.In vivo translation rates can substantially delay the cotranslational folding of the Escherichia coli cytosolic proteomeMechanisms of cellular proteostasis: insights from single-molecule approachesDesign of photocaged puromycin for nascent polypeptide release and spatiotemporal monitoring of translation.Nonnative helical motif in a chaperone-bound protein fragment.Increasing the sensitivity of NMR diffusion measurements by paramagnetic longitudinal relaxation enhancement, with application to ribosome-nascent chain complexesStructural characterization of the interaction of α-synuclein nascent chains with the ribosomal surface and trigger factorThe structural dynamics of macromolecular processes.Quantitative determination of ribosome nascent chain stability.Protein folding on the ribosome studied using NMR spectroscopy.Entropic stabilization of a deubiquitinase provides conformational plasticity and slow unfolding kinetics beneficial for functioning on the proteasomeThe ribosome in action: Tuning of translational efficiency and protein folding.Conjugation with polyamines enhances the antibacterial and anticancer activity of chloramphenicol.Folding of proteins with a flavodoxin-like architecture.The ribosome and its role in protein folding: looking through a magnifying glass.Force measurements of the disruption of the nascent polypeptide chain from the ribosome by optical tweezers.Single-molecule imaging of full protein synthesis by immobilized ribosomes.Site-specific solid-state NMR studies of "trigger factor" in complex with the large ribosomal subunit 50S.Chain dynamics of nascent polypeptides emerging from the ribosome.Confined dynamics of a ribosome-bound nascent globin: Cone angle analysis of fluorescence depolarization decays in the presence of two local motions.Ligand-driven vectorial folding of ribosome-bound human CFTR NBD1Sensitive proton-detected solid-state NMR spectroscopy of large proteins with selective CH3 labelling: application to the 50S ribosome subunit.The ribosome modulates nascent protein folding.Translation and folding of single proteins in real time.A strategy for co-translational folding studies of ribosome-bound nascent chain complexes using NMR spectroscopy.Unraveling co-translational protein folding: Concepts and methods.Prediction of variable translation rate effects on cotranslational protein folding.Kinetic modelling indicates that fast-translating codons can coordinate cotranslational protein folding by avoiding misfolded intermediates.Modeling the effect of codon translation rates on co-translational protein folding mechanisms of arbitrary complexity.NMR assignments of the peptidyl-prolyl cis-trans isomerase domain of trigger factor from E. coli.Large-scale purification of ribosome-nascent chain complexes for biochemical and structural studies.Solid-state NMR enhanced by dynamic nuclear polarization as a novel tool for ribosome structural biology
P2860
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P2860
Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy
@ast
Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy
@en
type
label
Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy
@ast
Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy
@en
prefLabel
Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy
@ast
Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy
@en
P2093
P2860
P50
P356
P1476
Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy
@en
P2093
Hélène Launay
John Christodoulou
Lisa D Cabrita
P2860
P304
16516-16521
P356
10.1073/PNAS.0704664104
P407
P577
2007-10-10T00:00:00Z