Cross-species transcriptional network analysis defines shared inflammatory responses in murine and human lupus nephritis
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Pro: 'The usefulness of biomarkers in glomerular diseases'. The problem: moving from syndrome to mechanism--individual patient variability in disease presentation, course and response to therapyCurrent perspectives on systems immunology approaches to rheumatic diseases.Applications of systems approaches in the study of rheumatic diseases.Silica Triggers Inflammation and Ectopic Lymphoid Neogenesis in the Lungs in Parallel with Accelerated Onset of Systemic Autoimmunity and Glomerulonephritis in the Lupus-Prone NZBWF1 MouseDemethylzeylasteral (T-96) Treatment Ameliorates Mice Lupus Nephritis Accompanied by Inhibiting Activation of NF-κB PathwayDrug repositioning in SLE: crowd-sourcing, literature-mining and Big Data analysis.MXRA5 is a TGF-β1-regulated human protein with anti-inflammatory and anti-fibrotic propertiesIntegrative biology identifies shared transcriptional networks in CKD.Human systems immunology: hypothesis-based modeling and unbiased data-driven approaches.Comparative transcriptional profiling of 3 murine models of SLE nephritis reveals both unique and shared regulatory networks.Biomarkers for kidney involvement in pediatric lupus.Structure and function of renal macrophages and dendritic cells from lupus-prone miceIdentification of stage-specific genes associated with lupus nephritis and response to remission induction in (NZB × NZW)F1 and NZM2410 mice.Identification of potential candidate genes for hypertensive nephropathy based on gene expression profile.Pristane-Accelerated Autoimmune Disease in (SWR X NZB) F1 Mice Leads to Prominent Tubulointerstitial Inflammation and Human Lupus Nephritis-Like Fibrosis.The Pathogenesis and Therapeutic Implications of Tubulointerstitial Inflammation in Human Lupus NephritisCharacterising the immune profile of the kidney biopsy at lupus nephritis flare differentiates early treatment responders from non-respondersWhat is damaging the kidney in lupus nephritis?Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarkerFrom single nucleotide polymorphism to transcriptional mechanism: a model for FRMD3 in diabetic nephropathy.A replication study from Chinese supports association between lupus-risk allele in TNFSF4 and renal disorder.Defining cell-type specificity at the transcriptional level in human diseaseBtk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis.Tet3-mediated hydroxymethylation of epigenetically silenced genes contributes to bone morphogenic protein 7-induced reversal of kidney fibrosis.Gene expression and regulation in systemic lupus erythematosus.Genomewide effects of peroxisome proliferator-activated receptor gamma in macrophages and dendritic cells--revealing complexity through systems biology.Molecular studies of lupus nephritis kidneys.Modular transcriptional repertoire analyses identify a blood neutrophil signature as a candidate biomarker for lupus nephritis.Overview of pathophysiology and treatment of human lupus nephritis.A systems approach to renal inflammation in SLE.The contribution of the programmed cell death machinery in innate immune cells to lupus nephritis.The Role of MicroRNAs and Human Epidermal Growth Factor Receptor 2 in Proliferative Lupus Nephritis.xHeinz: an algorithm for mining cross-species network modules under a flexible conservation model.Bcl3: a regulator of NF-κB inducible by TWEAK in acute kidney injury with anti-inflammatory and antiapoptotic properties in tubular cells.Non-canonical NFκB activation promotes chemokine expression in podocytesThe kidney biopsy in lupus nephritis: is it still relevant?Which B-cell subset should we target in lupus?Micro-RNA analysis of renal biopsies in human lupus nephritis demonstrates up-regulated miR-422a driving reduction of kallikrein-related peptidase 4.Bim suppresses the development of SLE by limiting myeloid inflammatory responses.Renal Macrophages and Dendritic Cells in SLE Nephritis.
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P2860
Cross-species transcriptional network analysis defines shared inflammatory responses in murine and human lupus nephritis
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Cross-species transcriptional ...... rine and human lupus nephritis
@ast
Cross-species transcriptional ...... rine and human lupus nephritis
@en
type
label
Cross-species transcriptional ...... rine and human lupus nephritis
@ast
Cross-species transcriptional ...... rine and human lupus nephritis
@en
prefLabel
Cross-species transcriptional ...... rine and human lupus nephritis
@ast
Cross-species transcriptional ...... rine and human lupus nephritis
@en
P2093
P2860
P50
P356
P1476
Cross-species transcriptional ...... rine and human lupus nephritis
@en
P2093
Celine C Berthier
Clemens D Cohen
Erwin P Bottinger
Maja Lindenmeyer
Matthias Kretzler
Meera Ramanujam
Tania Gonzalez-Rivera
Weijia Zhang
P2860
P304
P356
10.4049/JIMMUNOL.1103031
P407
P577
2012-06-20T00:00:00Z