Carbohydrates as the next frontier in pharmaceutical research.
about
Matrix-assisted laser desorption/ionization mass spectrometric analysis of uncomplexed highly sulfated oligosaccharides using ionic liquid matrices.Purification, cloning, and expression of an alpha/beta-galactoside alpha-2,3-sialyltransferase from a luminous marine bacterium, Photobacterium phosphoreum.Macromolecular scaffolds for immobilizing small molecule microarrays in label-free detection of protein-ligand interactions on solid support.Carbohydrate cluster microarrays fabricated on three-dimensional dendrimeric platforms for functional glycomics exploration.Determination of sulfate ester content in sulfated oligo- and poly-saccharides by capillary electrophoresis with indirect UV detection.Stereoselective synthesis of light-activatable perfluorophenylazide-conjugated carbohydrates for glycoarray fabrication and evaluation of structural effects on protein binding by SPR imaging.Sweetening the pot: adding glycosylation to the biomarker discovery equationMeasurement of enzymatic activity and specificity of human and avian influenza neuraminidases from whole virus by glycoarray and MALDI-TOF mass spectrometry.Flipping the paradigm on malaria transmission-blocking vaccines.Total synthesis of trifluorobutyryl-modified, globally protected sialyl Lewis x by a convergent [2+2] approachEngineering an antibiotic to fight cancer: optimization of the novobiocin scaffold to produce anti-proliferative agents.Synthesis of Carbohydrate Capped Silicon Nanoparticles and their Reduced Cytotoxicity, In Vivo Toxicity, and Cellular Uptake.Non-carbohydrate inhibitors of the lectin DC-SIGN.Click chemistry, a powerful tool for pharmaceutical sciences.Microplate-based characterization of protein-phosphoinositide binding interactions using a synthetic biotinylated headgroup analogue.Chemical approaches to perturb, profile, and perceive glycans.Cowpea mosaic virus capsid: a promising carrier for the development of carbohydrate based antitumor vaccines.Carbohydrate post-glycosylational modifications.Amino sugars and their mimetics via 1,2-oxazines.Discovery and design of carbohydrate-based therapeutics.Glycopolymers and glyco-nanoparticles in biomolecular recognition processes and vaccine development.Therapeutic potential of carbohydrate-based polymeric and nanoparticle systems.A Dilemma in the Glycosaminoglycan-Based Therapy: Synthetic or Naturally Unique Molecules?Dissecting molecular aspects of cell interactions using glycodendrimersomes with programmable glycan presentation and engineered human lectins.Tailored design and synthesis of heparan sulfate oligosaccharide analogues using sequential one-pot multienzyme systemsSynthetic Oligosaccharide Libraries and Microarray Technology: A Powerful Combination for the Success of Current Glycosaminoglycan Interactomics.Cell Factory Design and Optimization for the Stereoselective Synthesis of Polyhydroxylated Compounds.Dependence of neurotrophic factor activation of Trk tyrosine kinase receptors on cellular sialidase.Tetrafluorination of sugars as strategy for enhancing protein-carbohydrate affinity: application to UDP-Galp mutase inhibition.Benzylidene Acetal Protecting Group as Carboxylic Acid Surrogate: Synthesis of Functionalized Uronic Acids and Sugar Amino Acids.Nanoarchitectonics of biomolecular assemblies for functional applications.DNA glycoclusters and DNA-based carbohydrate microarrays: From design to applicationsSugar-installed thermoresponsive micellar aggregates self-assembled from “coil-comb-coil” triblock glycopolymers: preparation and recognition with Concanavalin AExpanding the Scope of Aminosugars: Synthesis of 2-Amino Septanosyl Glycoconjugates Using Septanosyl Fluoride DonorsReducing the conformational flexibility of carbohydrates: locking the 6-hydroxyl group by cyclopropanesGlycoconjugated Rhenium(I) and 99m-Technetium(I) Carbonyl Complexes from Pyridyltriazole Ligands Obtained by “Click Chemistry”Synthesis of 1,4-imino-L-lyxitols modified at C-5 and their evaluation as inhibitors of GH38 α-mannosidases
P2860
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P2860
Carbohydrates as the next frontier in pharmaceutical research.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Carbohydrates as the next frontier in pharmaceutical research.
@ast
Carbohydrates as the next frontier in pharmaceutical research.
@en
type
label
Carbohydrates as the next frontier in pharmaceutical research.
@ast
Carbohydrates as the next frontier in pharmaceutical research.
@en
prefLabel
Carbohydrates as the next frontier in pharmaceutical research.
@ast
Carbohydrates as the next frontier in pharmaceutical research.
@en
P356
P1476
Carbohydrates as the next frontier in pharmaceutical research.
@en
P2093
Daniel B Werz
Peter H Seeberger
P304
P356
10.1002/CHEM.200500025
P407
P577
2005-05-01T00:00:00Z