Interleukin-34 produced by human fibroblast-like synovial cells in rheumatoid arthritis supports osteoclastogenesis. - Wikidata - wikimedia - TriplyDB

Interleukin-34 produced by human fibroblast-like synovial cells in rheumatoid arthritis supports osteoclastogenesis.

Interleukin-34 produced by human fibroblast-like synovial cells in rheumatoid arthritis supports osteoclastogenesis.

http://www.wikidata.org/entity/Q36084929

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IL-34 induces the differentiation of human monocytes into immunosuppressive macrophages. antagonistic effects of GM-CSF and IFNγ Clinical biomarkers and pathogenic-related cytokines in rheumatoid arthritis Colony-stimulating factor (CSF) 1 receptor blockade reduces inflammation in human and murine models of rheumatoid arthritis CSF-1 receptor signaling in myeloid cells IL-34 Upregulated Th17 Production through Increased IL-6 Expression by Rheumatoid Fibroblast-Like Synoviocytes Regulation of Embryonic and Postnatal Development by the CSF-1 Receptor.Cytokine-modulating strategies and newer cytokine targets for arthritis therapy.Divergent antiviral roles of amphibian (Xenopus laevis) macrophages elicited by colony-stimulating factor-1 and interleukin-34.Integrative genomic analyses of a novel cytokine, interleukin-34 and its potential role in cancer prediction.The newly discovered cytokine IL-34 is expressed in gingival fibroblasts, shows enhanced expression by pro-inflammatory cytokines, and stimulates osteoclast differentiation.Osteoclasts: New Insights Interleukin-34 in rheumatoid arthritis: potential role in clinical therapy.Spleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in osteopetrotic op/op mice.Elevated Pentraxin 3 in bone metastatic breast cancer is correlated with osteolytic function.IL-34 and CSF-1: similarities and differences.Interkeukin-34, a cytokine crucial for the differentiation and maintenance of tissue resident macrophages and Langerhans cells.Induction of osteoclast progenitors in inflammatory conditions: key to bone destruction in arthritis.PTX3 stimulates osteoclastogenesis by increasing osteoblast RANKL production.Mediators of inflammation and bone remodeling in rheumatic disease.The dynamic evolution of rheumatology in Korea.Amphibian macrophage development and antiviral defenses.Increased IL-6 expression on THP-1 by IL-34 stimulation up-regulated rheumatoid arthritis Th17 cells.Functions of interleukin-34 and its emerging association with rheumatoid arthritis.A review on interleukins: The key manipulators in rheumatoid arthritis.Immunoregulatory properties of the cytokine IL-34.Interleukin-34 induces monocytic-like differentiation in leukemia cell lines.IL-34 Suppresses Candida albicans Induced TNFα Production in M1 Macrophages by Downregulating Expression of Dectin-1 and TLR2.p53 contributes to quercetin-induced apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes.Tumor necrosis factor-α induces interleukin-34 expression through nuclear factor‑κB activation in MC3T3-E1 osteoblastic cells IL-1β and TNFα promote monocyte viability through the induction of GM-CSF expression by rheumatoid arthritis synovial fibroblasts.Bone Loss in Rheumatoid Arthritis: Basic Mechanisms and Clinical Implications.1α,25-Dihydroxyvitamin D3 up-regulates IL-34 expression in SH-SY5Y neural cells.AG490 suppresses interleukin-34-mediated osteoclastogenesis in mice bone marrow macrophages.The cut-off value for interleukin 34 as an additional potential inflammatory biomarker for the prediction of the risk of diabetic complications.Interleukin-34 sustains inflammatory pathways in the gut.Bone- and cartilage-protective effects of a monoclonal antibody against colony-stimulating factor 1 receptor in experimental arthritis.Interleukin-34 Regulates Th1 and Th17 Cytokine Production by Activating Multiple Signaling Pathways through CSF-1R in Chicken Cell Lines.Regulation of Osteoclast Differentiation by Cytokine Networks.Bone erosions in rheumatoid arthritis: recent developments in pathogenesis and therapeutic implications Interleukin-34 Synovial Fluid Was Associated with Knee Osteoarthritis Severity: A Cross-Sectional Study in Knee Osteoarthritis Patients in Different Radiographic Stages

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Interleukin-34 produced by human fibroblast-like synovial cells in rheumatoid arthritis supports osteoclastogenesis.

http://www.wikidata.org/entity/Q36084929

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Chang-Keun Lee

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Dong Hyun Sohn

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Eun-Ju Chang

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Jae-Ho Chang

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Min Wook So

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Seung-Jun Hwang

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Soon-Suk Kang

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William H Robinson

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Yeon-Ho Chung

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P2860

Macrophage-colony stimulating factor and interleukin-34 induce chemokines in human whole blood

Discovery of a cytokine and its receptor by functional screening of the extracellular proteome

Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells

Fibroblast biology. Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis

Tumour necrosis factor-alpha stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-kappaB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b

The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis

Bone resorption by osteoclasts

Involvement of receptor activator of NFkappaB ligand and tumor necrosis factor-alpha in bone destruction in rheumatoid arthritis

Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems

Cytokines in the pathogenesis of rheumatoid arthritis

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