Thiopurine drugs in the treatment of childhood leukaemia: the influence of inherited thiopurine methyltransferase activity on drug metabolism and cytotoxicity.
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Human thiopurine methyltransferase activity varies with red blood cell ageThioguanine versus mercaptopurine for therapy of childhood lymphoblastic leukaemia: a comparison of haematological toxicity and drug metabolite concentrations.Therapeutic drug monitoring of antimetabolic cytotoxic drugs.Optimizing antimetabolite-based chemotherapy for the treatment of childhood acute lymphoblastic leukaemia.Review article: the treatment of inflammatory bowel disease with 6-mercaptopurine or azathioprine.Systemic Exposure to Thiopurines and Risk of Relapse in Children With Acute Lymphoblastic Leukemia: A Children's Oncology Group Study.Thiopurine methyltransferase activity is related to the risk of relapse of childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study.Pharmacogenetics and individualized therapy in children: immunosuppressants, antidepressants, anticancer and anti-inflammatory drugs.Recent advances using immunomodulators for inflammatory bowel disease.Interaction between NUDT15 and ABCC4 variants enhances intolerability of 6-mercaptopurine in Japanese patients with childhood acute lymphoblastic leukemia.The pharmacogenomics of drug resistance to protein kinase inhibitors.Evaluation of azathioprine-induced cytotoxicity in an in vitro rat hepatocyte system.Incorporation of 6-thioguanine nucleotides into DNA during maintenance therapy of childhood acute lymphoblastic leukemia-the influence of thiopurine methyltransferase genotypes.Pediatric inflammatory bowel disease: what children can teach adults.Assessment of mercaptopurine (6MP) metabolites and 6MP metabolic key-enzymes in childhood acute lymphoblastic leukemia.NUDT15 Variants Cause Hematopoietic Toxicity with Low 6-TGN Levels in Children with Acute Lymphoblastic Leukemia.Pharmacogenetically based dosing of thiopurines in childhood acute lymphoblastic leukemia: influence on cure rates and risk of second cancer.Insurance coverage for pharmacogenomic testing in the USALISA: a web-based decision-support system for trial management of childhood acute lymphoblastic leukaemia
P2860
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P2860
Thiopurine drugs in the treatment of childhood leukaemia: the influence of inherited thiopurine methyltransferase activity on drug metabolism and cytotoxicity.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Thiopurine drugs in the treatm ...... g metabolism and cytotoxicity.
@ast
Thiopurine drugs in the treatm ...... g metabolism and cytotoxicity.
@en
type
label
Thiopurine drugs in the treatm ...... g metabolism and cytotoxicity.
@ast
Thiopurine drugs in the treatm ...... g metabolism and cytotoxicity.
@en
prefLabel
Thiopurine drugs in the treatm ...... g metabolism and cytotoxicity.
@ast
Thiopurine drugs in the treatm ...... g metabolism and cytotoxicity.
@en
P2093
P1476
Thiopurine drugs in the treatm ...... g metabolism and cytotoxicity.
@en
P2093
P304
P356
10.1046/J.1365-2125.1997.T01-1-00607.X
P407
P577
1997-11-01T00:00:00Z