Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein-induced lysosomal translocation of proapoptotic effectors is mediated by phosphofurin acidic cluster sorting protein-2 (PACS-2)
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Inhibition of vacuolar ATPase attenuates the TRAIL-induced activation of caspase-8 and modulates the trafficking of TRAIL receptosomesThe endolysosomal system in cell death and survivalMIiSR: Molecular Interactions in Super-Resolution Imaging Enables the Analysis of Protein Interactions, Dynamics and Formation of Multi-protein StructuresCellular inhibitor of apoptosis (cIAP)-mediated ubiquitination of phosphofurin acidic cluster sorting protein 2 (PACS-2) negatively regulates tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) cytotoxicityAberrant DR5 transport through disruption of lysosomal function suggests a novel mechanism for receptor activationPathway reconstruction of airway remodeling in chronic lung diseases: a systems biology approach.Drugs acting on homeostasis: challenging cancer cell adaptation.The multifunctional sorting protein PACS-2 regulates SIRT1-mediated deacetylation of p53 to modulate p21-dependent cell-cycle arrest.Human NK cell lytic granules and regulation of their exocytosis58-F, a flavanone from Ophiopogon japonicus, prevents hepatocyte death by decreasing lysosomal membrane permeabilityThe role of anesthetic drugs in liver apoptosis.Apoptosis and necrosis in the liverCompartmentalization of TNF-related apoptosis-inducing ligand (TRAIL) death receptor functions: emerging role of nuclear TRAIL-R2.Mcl-1 is vital for neutrophil survival.Caught in the act - protein adaptation and the expanding roles of the PACS proteins in tissue homeostasis and disease.PACS-2 mediates the ATM and NF-κB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damageNoxa couples lysosomal membrane permeabilization and apoptosis during oxidative stress.Endosome traffic machinery meets the p53-p21 axis.Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.Alterations in Ca2+ Signalling via ER-Mitochondria Contact Site Remodelling in Cancer.A Recurrent De Novo PACS2 Heterozygous Missense Variant Causes Neonatal-Onset Developmental Epileptic Encephalopathy, Facial Dysmorphism, and Cerebellar Dysgenesis.Developing TRAIL/TRAIL death receptor-based cancer therapies.
P2860
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P2860
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein-induced lysosomal translocation of proapoptotic effectors is mediated by phosphofurin acidic cluster sorting protein-2 (PACS-2)
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Tumor necrosis factor-related ...... ter sorting protein-2 (PACS-2)
@ast
Tumor necrosis factor-related ...... ter sorting protein-2 (PACS-2)
@en
type
label
Tumor necrosis factor-related ...... ter sorting protein-2 (PACS-2)
@ast
Tumor necrosis factor-related ...... ter sorting protein-2 (PACS-2)
@en
prefLabel
Tumor necrosis factor-related ...... ter sorting protein-2 (PACS-2)
@ast
Tumor necrosis factor-related ...... ter sorting protein-2 (PACS-2)
@en
P2093
P2860
P356
P1476
Tumor necrosis factor-related ...... ter sorting protein-2 (PACS-2)
@en
P2093
Gary Thomas
Jimmy D Dikeakos
Laurel Thomas
Maria Eugenia Guicciardi
Nathan W Werneburg
Steve F Bronk
P2860
P304
24427-24437
P356
10.1074/JBC.M112.342238
P407
P577
2012-05-29T00:00:00Z