Critical determinants of human α-defensin 5 activity against non-enveloped viruses.
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Single, double and quadruple alanine substitutions at oligomeric interfaces identify hydrophobicity as the key determinant of human neutrophil alpha defensin HNP1 functionAntiviral mechanisms of human defensinsAn intrinsically disordered region of the adenovirus capsid is implicated in neutralization by human alpha defensin 5NMR Solution Structure and Condition-Dependent Oligomerization of the Antimicrobial Peptide Human Defensin 5High-quality 3D structures shine light on antibacterial, anti-biofilm and antiviral activities of human cathelicidin LL-37 and its fragments.Insights into Adenovirus Uncoating from Interactions with Integrins and Mediators of Host ImmunityDefensins at the Mucosal Surface: Latest Insights into Defensin-Virus InteractionsAntimicrobial peptides in the female reproductive tract: a critical component of the mucosal immune barrier with physiological and clinical implicationsThermodynamic instability of viral proteins is a pathogen-associated molecular pattern targeted by human defensinsAlpha-defensin-dependent enhancement of enteric viral infection.Delineation of interfaces on human alpha-defensins critical for human adenovirus and human papillomavirus inhibitionMolecular basis for self-assembly of a human host-defense peptide that entraps bacterial pathogensHuman defensins facilitate local unfolding of thermodynamically unstable regions of bacterial protein toxins.Anti-HIV activity of human defensin 5 in primary CD4+ T cells under serum-deprived conditions is a consequence of defensin-mediated cytotoxicityAlpha-defensin HD5 inhibits furin cleavage of human papillomavirus 16 L2 to block infection.A small intestinal organoid model of non-invasive enteric pathogen-epithelial cell interactions.Defensins and viral infection: dispelling common misconceptions.Viruses and the Microbiota.Defensins Potentiate a Neutralizing Antibody Response to Enteric Viral Infection.Cationic host defence peptides: potential as antiviral therapeuticsThe human alpha defensin HD5 neutralizes JC polyomavirus infection by reducing endoplasmic reticulum traffic and stabilizing the viral capsid.Secreted mucosal antimicrobials in the female reproductive tract that are important to consider for HIV prevention.α-Defensin HD5 Inhibits Human Papillomavirus 16 Infection via Capsid Stabilization and Redirection to the LysosomeTargeting and inactivation of bacterial toxins by human defensins.Key Determinants of Human α-Defensin 5 and 6 for Enhancement of HIV Infectivity.Neutralization of Virus Infectivity by Antibodies: Old Problems in New Perspectives.Epidemiological and genetic analysis concerning the coxsackievirus A6 related endemic outbreak of hand-foot-mouth disease in Taizhou, China, during 2013.Conformational landscape and pathway of disulfide bond reduction of human alpha defensin.Towards the Application of Human Defensins as Antivirals.
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P2860
Critical determinants of human α-defensin 5 activity against non-enveloped viruses.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Critical determinants of human α-defensin 5 activity against non-enveloped viruses.
@ast
Critical determinants of human α-defensin 5 activity against non-enveloped viruses.
@en
type
label
Critical determinants of human α-defensin 5 activity against non-enveloped viruses.
@ast
Critical determinants of human α-defensin 5 activity against non-enveloped viruses.
@en
prefLabel
Critical determinants of human α-defensin 5 activity against non-enveloped viruses.
@ast
Critical determinants of human α-defensin 5 activity against non-enveloped viruses.
@en
P2093
P2860
P356
P1476
Critical determinants of human α-defensin 5 activity against non-enveloped viruses
@en
P2093
Anshu P Gounder
Mayim E Wiens
Sarah S Wilson
P2860
P304
24554-24562
P356
10.1074/JBC.M112.354068
P407
P577
2012-05-25T00:00:00Z