Modulation of the Brd4/P-TEFb interaction by the human T-lymphotropic virus type 1 tax protein.
about
The HTLV-1 Tax interactome7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcriptionP-TEFb goes viralAbrogation of the Brd4-positive transcription elongation factor B complex by papillomavirus E2 protein contributes to viral oncogene repressionPapillomavirus interaction with cellular chromatin.Protein phosphatase-1 activates CDK9 by dephosphorylating Ser175.Human T-lymphotropic virus type 1 Tax protein complexes with P-TEFb and competes for Brd4 and 7SK snRNP/HEXIM1 binding.The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.Perturbation of BRD4 protein function by BRD4-NUT protein abrogates cellular differentiation in NUT midline carcinomaInhibition of geranylgeranyl transferase-I decreases cell viability of HTLV-1-transformed cells.FACT Proteins, SUPT16H and SSRP1, Are Transcriptional Suppressors of HIV-1 and HTLV-1 That Facilitate Viral LatencyThe interaction of the gammaherpesvirus 68 orf73 protein with cellular BET proteins affects the activation of cell cycle promoters.Recruitment of cdk9 to the immediate-early viral transcriptosomes during human cytomegalovirus infection requires efficient binding to cyclin T1, a threshold level of IE2 86, and active transcription.Differential effects of HTLV-1 Tax oncoprotein on the different estrogen-induced-ER α-mediated transcriptional activities.Regulation of aurora B expression by the bromodomain protein Brd4.Deregulations in the cyclin-dependent kinase-9-related pathway in cancer: implications for drug discovery and development.The MHC-II transactivator CIITA, a restriction factor against oncogenic HTLV-1 and HTLV-2 retroviruses: similarities and differences in the inhibition of Tax-1 and Tax-2 viral transactivators.P-TEFb goes viral.Sporadic on/off switching of HTLV-1 Tax expression is crucial to maintain the whole population of virus-induced leukemic cells.
P2860
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P2860
Modulation of the Brd4/P-TEFb interaction by the human T-lymphotropic virus type 1 tax protein.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Modulation of the Brd4/P-TEFb ...... opic virus type 1 tax protein.
@ast
Modulation of the Brd4/P-TEFb ...... opic virus type 1 tax protein.
@en
type
label
Modulation of the Brd4/P-TEFb ...... opic virus type 1 tax protein.
@ast
Modulation of the Brd4/P-TEFb ...... opic virus type 1 tax protein.
@en
prefLabel
Modulation of the Brd4/P-TEFb ...... opic virus type 1 tax protein.
@ast
Modulation of the Brd4/P-TEFb ...... opic virus type 1 tax protein.
@en
P2093
P2860
P356
P1433
P1476
Modulation of the Brd4/P-TEFb ...... opic virus type 1 tax protein.
@en
P2093
John N Brady
Keiko Ozato
Keven Huang
Meisheng Zhou
Moon Kyoo Jang
Soo-Jin Jeong
Won-Kyung Cho
P2860
P304
11179-11186
P356
10.1128/JVI.00408-07
P407
P577
2007-08-08T00:00:00Z