Increased levels of COX-2 and prostaglandin E2 contribute to elevated aromatase expression in inflamed breast tissue of obese women. - Wikidata - wikimedia - TriplyDB

Increased levels of COX-2 and prostaglandin E2 contribute to elevated aromatase expression in inflamed breast tissue of obese women.

Increased levels of COX-2 and prostaglandin E2 contribute to elevated aromatase expression in inflamed breast tissue of obese women.

http://www.wikidata.org/entity/Q36099670

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Evidence to Support the Anti-Cancer Effect of Olive Leaf Extract and Future Directions Parturition dysfunction in obesity: time to target the pathobiology The Interactions of Obesity, Inflammation and Insulin Resistance in Breast Cancer Obesity and cancer: mechanistic insights from transdisciplinary studies Multiple drug resistance-associated protein 4 (MRP4), prostaglandin transporter (PGT), and 15-hydroxyprostaglandin dehydrogenase (15-PGDH) as determinants of PGE2 levels in cancer Harnessing the genome for characterization of G-protein coupled receptors in cancer pathogenesis The beneficial role of vitamin D in obesity: possible genetic and cell signaling mechanisms Reducing the Risk of Breast Cancer Recurrence: an Evaluation of the Effects and Mechanisms of Diet and Exercise CYP19A1 promoter methylation in saliva associated with milestones of pubertal timing in urban girls From obesity to cancer: a review on proposed mechanisms.Cyclooxygenase-2 and the inflammogenesis of breast cancer.Favorable modulation of benign breast tissue and serum risk biomarkers is associated with > 10 % weight loss in postmenopausal women.Network Marker Selection for Untargeted LC-MS Metabolomics Data.Minireview: Obesity and breast cancer: a tale of inflammation and dysregulated metabolism Inflammation of mammary adipose tissue occurs in overweight and obese patients exhibiting early-stage breast cancer Use of nonsteroidal anti-inflammatory drugs and reduced breast cancer risk among overweight women.Aspirin and serum estrogens in postmenopausal women: a randomized controlled clinical trial.Impact of COX2 genotype, ER status and body constitution on risk of early events in different treatment groups of breast cancer patients.n-3 polyunsaturated fatty acids and mechanisms to mitigate inflammatory paracrine signaling in obesity-associated breast cancer.Urinary prostaglandin E2 metabolite and breast cancer risk.Brown fat determination and development from muscle precursor cells by novel action of bone morphogenetic protein 6 Lipid Signaling in Tumorigenesis.Obesity-associated systemic interleukin-6 promotes pre-adipocyte aromatase expression via increased breast cancer cell prostaglandin E2 production.Menopause is a determinant of breast adipose inflammation The Role of the Insulin/IGF System in Cancer: Lessons Learned from Clinical Trials and the Energy Balance-Cancer Link.Cellular Expression of Cyclooxygenase, Aromatase, Adipokines, Inflammation and Cell Proliferation Markers in Breast Cancer Specimen.Lifetime use of nonsteroidal anti-inflammatory drugs and breast cancer risk: results from a prospective study of women with a sister with breast cancer.Estrogen Protects against Obesity-Induced Mammary Gland Inflammation in Mice.Nonsteroidal Anti-Inflammatory Drug and Aspirin Use in Relation to Lung Cancer Risk among Postmenopausal Women.Targeting the COX-2 Pathway to Improve Therapeutic Response in the Obese Breast Cancer Patient Population Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1 PPARγ agonists target aromatase via both PGE2 and BRCA1.Targeting obesity-related adipose tissue dysfunction to prevent cancer development and progression.Retinoids and rexinoids in cancer prevention: from laboratory to clinic.Tumor-associated macrophages: unwitting accomplices in breast cancer malignancy.Identification of macrophage extracellular trap-like structures in mammary gland adipose tissue: a preliminary study.Caloric restriction reverses obesity-induced mammary gland inflammation in mice.Obesity, energy balance, and cancer: new opportunities for prevention Systemic Correlates of White Adipose Tissue Inflammation in Early-Stage Breast Cancer.HIF-1α stimulates aromatase expression driven by prostaglandin E2 in breast adipose stroma.

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P2860

Increased levels of COX-2 and prostaglandin E2 contribute to elevated aromatase expression in inflamed breast tissue of obese women.

http://www.wikidata.org/entity/Q36099670

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Increased levels of COX-2 and ...... breast tissue of obese women.

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Increased levels of COX-2 and ...... breast tissue of obese women.

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Cancer Discovery

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Increased levels of COX-2 and ...... breast tissue of obese women.

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Andrew J Dannenberg

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Baoheng Du

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Clifford A Hudis

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Dilip Giri

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Kotha Subbaramaiah

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Levy Kopelovich

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Patrick G Morris

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Xi Kathy Zhou

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P2860

Protein measurement with the Folin phenol reagent

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Obesity is associated with macrophage accumulation in adipose tissue

Association of frequency and duration of aspirin use and hormone receptor status with breast cancer risk

Celecoxib for the prevention of sporadic colorectal adenomas

Macrophages, inflammation, and insulin resistance

Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance.

Aromatase--a brief overview.

Targeting cyclooxygenase-2 in human neoplasia: rationale and promise.

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