The basic helix-loop-helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression.
about
Bridge-1, a novel PDZ-domain coactivator of E2A-mediated regulation of insulin gene transcriptionRepression of TFII-I-dependent transcription by nuclear exclusionSynergistic activation of the human orphan nuclear receptor SHP gene promoter by basic helix-loop-helix protein E2A and orphan nuclear receptor SF-1Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient miceNeuroD1/E47 regulates the E-box element of a novel zinc finger transcription factor, IA-1, in developing nervous system.Novel transcriptional potentiation of BETA2/NeuroD on the secretin gene promoter by the DNA-binding protein Finb/RREB-1.Basic helix-loop-helix transcription factors and enteroendocrine cell differentiationNeuroD1/beta2 contributes to cell-specific transcription of the proopiomelanocortin geneBile acids inhibit duodenal secretin expression via orphan nuclear receptor small heterodimer partner (SHP)Transcription factor regulation of pancreatic organogenesis, differentiation and maturationCyclin D1 represses the basic helix-loop-helix transcription factor, BETA2/NeuroDThe basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimerNeurogenin and NeuroD direct transcriptional targets and their regulatory enhancersSecretin deficiency causes impairment in survival of neural progenitor cells in miceThe basic helix-loop-helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cellsDeregulation of CREB signaling pathway induced by chronic hyperglycemia downregulates NeuroD transcriptionp300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene.Review article: transcriptional events controlling the terminal differentiation of intestinal endocrine cells.Role of phospholipase D1 in glucose-induced insulin secretion in pancreatic Beta cells.The NeuroD1/BETA2 sequences essential for insulin gene transcription colocalize with those necessary for neurogenesis and p300/CREB binding protein bindingRegulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3.Specific protein-protein interaction between basic helix-loop-helix transcription factors and homeoproteins of the Pitx family.HES-1 repression of differentiation and proliferation in PC12 cells: role for the helix 3-helix 4 domain in transcription repression.Identification of RANBP16 and RANBP17 as novel interaction partners for the bHLH transcription factor E12.Using the Tg(nrd:egfp)/albino zebrafish line to characterize in vivo expression of neurod.Impaired enteroendocrine development in intestinal-specific Islet1 mouse mutants causes impaired glucose homeostasis.Melatonin-receptor-1-deficiency affects neurogenic differentiation factor immunoreaction in pancreatic islets and enteroendocrine cells of mice.Cross-talk between distinct nuclear import pathways enables efficient nuclear import of E47 in conjunction with its partner transcription factorsHarnessing the gut to treat diabetes.NeuroD1 gene and interleukin-18 gene polymorphisms in type 1 diabetes in Dalmatian population of Southern Croatia.Glucose mediates the translocation of NeuroD1 by O-linked glycosylation.Wnt3a upregulates brain-derived insulin by increasing NeuroD1 via Wnt/β-catenin signaling in the hypothalamus.Targeted disruption of NeuroD, a proneural basic helix-loop-helix factor, impairs distal lung formation and neuroendocrine morphology in the neonatal lungNeurogenic differentiation factor NeuroD confers protection against radiation-induced intestinal injury in mice.The novel enterochromaffin marker Lmx1a regulates serotonin biosynthesis in enteroendocrine cell lineages downstream of Nkx2.2.Generation of functional insulin-producing cells from mouse embryonic stem cells through 804G cell-derived extracellular matrix and protein transduction of transcription factors.Gut endocrine cell development.Extragastrointestinal functions and transcriptional regulation of secretin and secretin receptors.Can the 'neuron theory' be complemented by a universal mechanism for generic neuronal differentiation.Secretin activation of chromogranin A gene transcription. Identification of the signaling pathways in cis and in trans.
P2860
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P2860
The basic helix-loop-helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
The basic helix-loop-helix tra ...... ates secretin gene expression.
@ast
The basic helix-loop-helix tra ...... ates secretin gene expression.
@en
type
label
The basic helix-loop-helix tra ...... ates secretin gene expression.
@ast
The basic helix-loop-helix tra ...... ates secretin gene expression.
@en
prefLabel
The basic helix-loop-helix tra ...... ates secretin gene expression.
@ast
The basic helix-loop-helix tra ...... ates secretin gene expression.
@en
P2093
P2860
P356
P1476
The basic helix-loop-helix tra ...... ates secretin gene expression.
@en
P2093
P2860
P304
P356
10.1073/PNAS.94.8.3560
P407
P577
1997-04-01T00:00:00Z